Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Todd W. Bauer"'
Autor:
Philip I. Chow, Devin G. Roller, Mehdi Boukhechba, Kelly M. Shaffer, Lee M. Ritterband, Matthew J. Reilley, Tri M. Le, Paul R. Kunk, Todd W. Bauer, Daniel G. Gioeli
Publikováno v:
Internet Interventions, Vol 34, Iss , Pp 100644- (2023)
As mobile and wearable devices continue to grow in popularity, there is strong yet unrealized potential to harness people's mobile sensing data to improve our understanding of their cellular and biologically-based diseases. Breakthrough technical inn
Externí odkaz:
https://doaj.org/article/c768ed8615f84bf284ffb233c114678b
Autor:
Karol Szlachta, Cem Kuscu, Turan Tufan, Sara J. Adair, Stephen Shang, Alex D. Michaels, Matthew G. Mullen, Natasha Lopes Fischer, Jiekun Yang, Limin Liu, Prasad Trivedi, Edward B. Stelow, P. Todd Stukenberg, J. Thomas Parsons, Todd W. Bauer, Mazhar Adli
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Predicting the response to chemotherapy is a major goal of cancer research. Here the authors use CRISPR knockout screens in pancreatic ductal adenocarcinoma cells to identify deletions synergistic with MEK inhibitors.
Externí odkaz:
https://doaj.org/article/5878576fa2b34029942f52a332a9c423
Autor:
Sarbajeet Nagdas, Jennifer A. Kashatus, Aldo Nascimento, Syed S. Hussain, Riley E. Trainor, Sarah R. Pollock, Sara J. Adair, Alex D. Michaels, Hiromi Sesaki, Edward B. Stelow, Todd W. Bauer, David F. Kashatus
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1845-1859.e5 (2019)
Summary: Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRasG12V promotes mitochondrial fragmentation and tumor growth through Erk
Externí odkaz:
https://doaj.org/article/3897e3f059e04a41b0a0865493500ca3
Autor:
James M. Lindberg, Timothy E. Newhook, Sara J. Adair, Dustin M. Walters, Alison J. Kim, Edward B. Stelow, J. Thomas Parsons, Todd W. Bauer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 562-571 (2014)
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and epidermal growth factor receptor (EGFR) family signaling are drivers of tumorigenesis in pancreatic ductal adenocarcinoma (PDAC). Previous studies have demonstrated that combinatorial tr
Externí odkaz:
https://doaj.org/article/30740983972940199a2365ff81e3d51a
Autor:
Dustin M. Walters, James M. Lindberg, Sara J. Adair, Timothy E. Newhook, Catharine R. Cowan, Jayme B. Stokes, Cheryl A. Borgman, Edward B. Stelow, Bryce T. Lowrey, Maria E. Chopivsky, Tona M. Gilmer, John T. Parsons, Todd W. Bauer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 2, Pp 143-155 (2013)
Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human EGFR2 (HER2) is observed frequent in pancreatic adenocarcinomas. Because of co-activation of these
Externí odkaz:
https://doaj.org/article/9fb804b7b7d4409cb4093fdefaf8b552
Autor:
Laura Alaimo, Zorays Moazzam, Yutaka Endo, Henrique A. Lima, Swatika P. Butey, Andrea Ruzzenente, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W. Bauer, Sorin Alexandrescu, George A. Poultsides, Shishir K. Maithel, Hugo P. Marques, Guillaume Martel, Carlo Pulitano, Feng Shen, François Cauchy, Bas Groot Koerkamp, Itaru Endo, Minoru Kitago, Alex Kim, Aslam Ejaz, Joal Beane, Jordan Cloyd, Timothy M. Pawlik
Publikováno v:
Annals of Surgical Oncology. Springer New York
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is associated with poor long-term outcomes, and limited evidence exists on optimal resection margin width. This study used artificial intelligence to investigate long-term outcomes and optimal margin
Autor:
Yutaka Endo, Kazunari Sasaki, Zorays Moazzam, Henrique A. Lima, Laura Alaimo, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W. Bauer, Sorin Alexandrescu, George A. Poultsides, Minoru Kitago, Shishir K. Maithel, Hugo P. Marques, Guillaume Martel, Carlo Pulitano, Feng Shen, François Cauchy, Bas Groot Koerkamp, Itaru Endo, Timothy M. Pawlik
Publikováno v:
Annals of Surgical Oncology, 30(4), 2023-2032. Springer New York
BACKGROUND: The present study aimed to examine the prognostic significance of margin status following hepatectomy of intrahepatic cholangiocarcinoma (ICC) relative to overall tumor burden and nodal status.METHOD: Patients who underwent curative-inten
Autor:
Laura Alaimo, Zorays Moazzam, Yutaka Endo, Henrique A. Lima, Andrea Ruzzenente, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W. Bauer, Sorin Alexandrescu, George A. Poultsides, Shishir K. Maithel, Hugo P. Marques, Guillaume Martel, Carlo Pulitano, Feng Shen, François Cauchy, Bas Groot Koerkamp, Itaru Endo, Timothy M. Pawlik
Publikováno v:
Annals of Surgical Oncology, 30(3), 1392-1403. Springer New York
INTRODUCTION: While generally associated with poor prognosis, intrahepatic cholangiocarcinoma (ICC) can have a heterogeneous presentation and natural history. We sought to identify specific ICC subtypes that may be associated with varied long-term ou
Autor:
Xu-Feng Zhang, Feng Xue, Matthew Weiss, Irinel Popescu, Hugo P. Marques, Luca Aldrighetti, Shishir K. Maithel, Carlo Pulitano, Todd W. Bauer, Feng Shen, George A. Poultsides, François Cauchy, Guillaume Martel, B. Groot Koerkamp, Endo Itaru, Yi Lv, Timothy M. Pawlik
Publikováno v:
Annals of Surgical Oncology, 30(3), 1424-1433. Springer New York
BACKGROUND: We sought to investigate whether the unique lateral patterns of lymphatic drainage impacted lymphadenectomy (LND), lymph node metastasis (LNM), and long-term survival of patients after curative hemi-hepatectomy for left- versus right-side
Autor:
Yutaka Endo, Zorays Moazzam, Laura Alaimo, Henrique A. Lima, Muhammad M. Munir, Chanza F. Shaikh, Alfredo Guglielmi, Luca Aldrighetti, Matthew Weiss, Todd W. Bauer, Sorin Alexandrescu, George A. Poultsides, Minoru Kitago, Shishir K. Maithel, Hugo P. Marques, Guillaume Martel, Carlo Pulitano, Feng Shen, François Cauchy, Bas G. Koerkamp, Itaru Endo, Timothy M. Pawlik
Publikováno v:
HPB, 25(2), 229-238. John Wiley & Sons Inc.
Background: The aim of this study was to develop a predictive model to identify individuals most likely to derive overall survival (OS) benefit from adjuvant chemotherapy (AC) after hepatic resection of intrahepatic cholangiocarcinoma (ICC). Methods: