Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Todd W Mitchell"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163972 (2016)
In preeclampsia, maternal insulin resistance leads to defective expansion of adipocytes, enhanced adipocyte lipolysis, up-regulation of very low density lipoprotein synthesis, maternal hypertriglyceridaemia and the potential for ectopic fat storage.
Externí odkaz:
https://doaj.org/article/4bfc2fd8afe144f2bfd234eb12612159
Autor:
Jessica R Hughes, Vladimir A Levchenko, Stephen J Blanksby, Todd W Mitchell, Alan Williams, Roger JW Truscott
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/5714dd021057429c810ad2bbba2d63d3
Autor:
Jessica R Hughes, Vladimir A Levchenko, Stephen J Blanksby, Todd W Mitchell, Alan Williams, Roger JW Truscott
Publikováno v:
eLife, Vol 4 (2015)
Lipids are critical to cellular function and it is generally accepted that lipid turnover is rapid and dysregulation in turnover results in disease (Dawidowicz 1987; Phillips et al., 2009; Liu et al., 2013). In this study, we present an intriguing co
Externí odkaz:
https://doaj.org/article/7390125c124a4e38a7663b80c39bd7c6
Autor:
Danni Cheng, Andrew M Jenner, Guanghou Shui, Wei Fun Cheong, Todd W Mitchell, Jessica R Nealon, Woojin S Kim, Heather McCann, Markus R Wenk, Glenda M Halliday, Brett Garner
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17299 (2011)
BackgroundWe present a lipidomics analysis of human Parkinson's disease tissues. We have focused on the primary visual cortex, a region that is devoid of pathological changes and Lewy bodies; and two additional regions, the amygdala and anterior cing
Externí odkaz:
https://doaj.org/article/eb0e9b627a6442e8b6633f95c48d193c
Autor:
Maximus Berger, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R. Schäfer, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Todd W. Mitchell, Barbara J. Meyer, Andrew Thompson, Alison Ruth Yung, Patrick D. McGorry, G. Paul Amminger
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/40f78615095149b8b106023c773e4673
Autor:
Maximus Berger, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R. Schäfer, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Todd W. Mitchell, Barbara J. Meyer, Andrew Thompson, Alison Ruth Yung, Patrick D. McGorry, G. Paul Amminger
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
BackgroundDeficiencies in membrane polyunsaturated fatty acids (PUFA) such as omega-3 (n-3) fatty acids are thought to contribute to the pathophysiological processes underlying psychotic disorders. Emerging evidence suggests that the levels of PUFA a
Externí odkaz:
https://doaj.org/article/df0c2ce4a5e24a5aa8a784f6408c8c23
Autor:
Jeffrey G. McDonald, Christer S. Ejsing, Dominik Kopczynski, Michal Holčapek, Junken Aoki, Makoto Arita, Masanori Arita, Erin S. Baker, Justine Bertrand-Michel, John A. Bowden, Britta Brügger, Shane R. Ellis, Maria Fedorova, William J. Griffiths, Xianlin Han, Jürgen Hartler, Nils Hoffmann, Jeremy P. Koelmel, Harald C. Köfeler, Todd W. Mitchell, Valerie B. O’Donnell, Daisuke Saigusa, Dominik Schwudke, Andrej Shevchenko, Candice Z. Ulmer, Markus R. Wenk, Michael Witting, Denise Wolrab, Yu Xia, Robert Ahrends, Gerhard Liebisch, Kim Ekroos
Publikováno v:
Nature metabolism. 4(9)
The rapid increase in lipidomic data has triggered a community-based movement to develop guidelines and minimum requirements for generating, reporting and publishing lipidomic data. The creation of a dynamic checklist summarizing key details of lipid
Autor:
Gabrielle R. Phillips, Sarah E. Hancock, Andrew M. Jenner, Catriona McLean, Kelly A. Newell, Todd W. Mitchell
Publikováno v:
Nutrients; Volume 14; Issue 10; Pages: 2086
Huntington’s disease (HD) is a genetic, neurodegenerative illness that onsets in late adulthood as a series of progressive and terminal cognitive, motor, and psychiatric deficits. The disease is caused by a polyQ mutation in the Huntingtin gene (HT
Autor:
Connie Markulev, Dorien H. Nieman, Monika Schlögelhofer, Maximus Berger, Ian B. Hickie, Anita Riecher-Rössler, G. Paul Amminger, Hok Pan Yuen, Stefan Smesny, Eric Y.H. Chen, Swapna Verma, Andrew Thompson, Miriam R. Schäfer, Nilufar Mossaheb, Barnaby Nelson, Todd W. Mitchell, Barbara J. Meyer, Gregor Berger, Alison R. Yung, Patrick D. McGorry, Ayedh Alqarni, Merete Nordentoft, Lieuwe de Haan
Publikováno v:
Schizophrenia research, 226, 44-51. Elsevier
People classified as ultra-high risk (UHR) of developing psychosis have reduced cellular membrane omega-3 and omega-6 polyunsaturated fatty acids (PUFA). We aimed to compare omega-3 index, fatty acids and molecular phospholipid species from erythrocy
Autor:
Dorien H. Nieman, Monika Schlögelhofer, Connie Markulev, Eric Y.H. Chen, Hok Pan Yuen, Lieuwe de Haan, Ian B. Hickie, Anita Riecher-Rössler, S. Smesny, Barnaby Nelson, Patrick D. McGorry, Todd W. Mitchell, Andrew Thompson, Merete Nordentoft, Barbara J. Meyer, Gregor Berger, Maximus Berger, Ayedh Alqarni, G. Paul Amminger, Alison R. Yung, Swapna Verma, Miriam R. Schäfer, Nilufar Mossaheb
Publikováno v:
Schizophrenia research, 226, 52-60. Elsevier
Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) are necessary for optimum mental health, with recent studies showing low n-3 LCPUFA in people at ultra-high risk (UHR) of developing psychosis. Furthermore, people at UHR of psychosis had in