Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Todd T Schlegel"'
Autor:
Constantin-Cristian Topriceanu, Eesha Dev, Mahmood Ahmad, Rebecca Hughes, Hunain Shiwani, Matthew Webber, Kenan Direk, Andrew Wong, Martin Ugander, James C. Moon, Alun D. Hughes, Jane Maddock, Todd T. Schlegel, Gabriella Captur
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships betwe
Externí odkaz:
https://doaj.org/article/e91430dc36f344b3b9b0d182e9b29e69
Autor:
Maren Maanja, Todd T. Schlegel, Fredrika Fröjdh, Louise Niklasson, Björn Wieslander, Ljuba Bacharova, Erik B. Schelbert, Martin Ugander
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The electrocardiogram (ECG) and cardiovascular magnetic resonance imaging (CMR) provide powerful prognostic information. The aim was to determine their relative prognostic value. Patients (n = 783) undergoing CMR and 12-lead ECG with a QRS d
Externí odkaz:
https://doaj.org/article/e8882e17deb94d8f802b28ab7cabba60
Autor:
Maren Maanja, Todd T. Schlegel, Rebecca Kozor, Ljuba Bacharova, Timothy C. Wong, Erik B. Schelbert, Martin Ugander
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Electrocardiographic (ECG) signs of left ventricular hypertrophy (LVH) lack sensitivity. The aim was to identify LVH based on an abnormal spatial peaks QRS-T angle, evaluate its diagnostic performance compared to conventional ECG criteria fo
Externí odkaz:
https://doaj.org/article/3a5ff4b312c74f26b4b6e55ce72e70a0
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Electrocardiographic (ECG) Heart Age conveying cardiovascular risk has been estimated by both Bayesian and artificial intelligence approaches. We hypothesised that explainable measures from the 10-s 12-lead ECG could successfully predict Bay
Externí odkaz:
https://doaj.org/article/0d1755ddcde84922bd35bf238838e8a0
Autor:
Malin Hildenborg, Jessica Kåhlin, Fredrik Granath, Anna Schening, Anna Granström, Anette Ebberyd, Lena Klevenvall, Henrik Zetterberg, Jinming Han, Todd T. Schlegel, Robert Harris, Helena Erlandsson Harris, Lars I. Eriksson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Surgery triggers a systemic inflammatory response that ultimately impacts the brain and associates with long-term cognitive impairment. Adequate regulation of this immune surge is pivotal for a successful surgical recovery. We explored the temporal i
Externí odkaz:
https://doaj.org/article/0d687330368942378f2c3183a93f08ae
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Background. Sudden cardiac death (SCD) is the single major cause of death in hemodialysis (HD) patients. QRS-T angle is an established marker of global repolarization heterogeneity associated with electrical instability and SCD. Heat shock protein 27
Externí odkaz:
https://doaj.org/article/8fe754200d4c42eb9964c1ffe9a53f47
Autor:
Patrick A. Gladding, Maxine Cooper, Renee Young, Suzanne Loader, Kevin Smith, Erica Zarate, Saras Green, Silas G. Villas Boas, Phillip Shepherd, Purvi Kakadiya, Eric Thorstensen, Christine Keven, Margaret Coe, Mia Jüllig, Edmond Zhang, Todd T. Schlegel
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 13 (2022)
Background: Multi-omics delivers more biological insight than targeted investigations. We applied multi-omics to patients with heart failure with reduced ejection fraction (HFrEF). Methods: 46 patients with HFrEF and 20 controls underwent metabolomic
Externí odkaz:
https://doaj.org/article/6374c7d662d140f09584a5c6ea2f16ee
Autor:
Zak, Loring, Anna, Giczewska, Paul, Hofmann, Karen, Chiswell, Todd T, Schlegel, Martin, Ugander, Kevin P, Jackson, Jonathan P, Piccini, Brett D, Atwater
Publikováno v:
Journal of Electrocardiology. 77:17-22
Chronic right ventricular (RV) pacing can induce left ventricular (LV) dyssynchrony and cause pacemaker induced cardiomyopathy (PiCM). Identifying which patients are at risk for PiCM is limited.Patients receiving RV-only permanent pacemakers (PPMs) a
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Externí odkaz:
https://doaj.org/article/689b00db359d49a89582b180af3080fd