Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Todd P.W. McMullen"'
Autor:
Michele Pelosi, Eric Testet, Soazig Le Lay, Isabelle Dugail, Xiaoyun Tang, Guillaume Mabilleau, Yamina Hamel, Marine Madrange, Thomas Blanc, Thierry Odent, Todd P.W. McMullen, Marco Alfò, David N. Brindley, Pascale de Lonlay
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 12, Pp 2348-2364 (2017)
Lipin-1 is a Mg2+-dependent phosphatidic acid phosphatase (PAP) that in mice is necessary for normal glycerolipid biosynthesis, controlling adipocyte metabolism, and adipogenic differentiation. Mice carrying inactivating mutations in the Lpin1 gene d
Externí odkaz:
https://doaj.org/article/cf817ac8be29467abb21d280db7df091
Autor:
Ana Lopez-Campistrous, Esther Ekpe Adewuyi, Matthew G.K. Benesch, Yi Man Ko, Raymond Lai, Aducio Thiesen, Jay Dewald, Peng Wang, Karen Chu, Sunita Ghosh, David C. Williams, Larissa J. Vos, David N. Brindley, Todd P.W. McMullen
Publikováno v:
EBioMedicine, Vol 12, Iss C, Pp 86-97 (2016)
Dedifferentiation of follicular cells is a central event in resistance to radioactive iodine and patient mortality in papillary thyroid carcinoma (PTC). We reveal that platelet derived growth factor receptor alpha (PDGFRα) specifically drives dediff
Externí odkaz:
https://doaj.org/article/c5c4da49361e49e0a54a8697243b501a
Autor:
Xiaoyun Tang, Matthew G.K. Benesch, Jay Dewald, Yuan Y. Zhao, Neeraj Patwardhan, Webster L. Santos, Jonathan M. Curtis, Todd P.W. McMullen, David N. Brindley
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2389-2400 (2014)
Lipid phosphate phosphatase-1 (LPP1) degrades lysophosphatidate (LPA) and attenuates receptor-mediated signaling. LPP1 expression is low in many cancer cells and tumors compared with normal tissues. It was hypothesized from studies with cultured cell
Externí odkaz:
https://doaj.org/article/2d44e8bac66f4097aa70ac4671a8ac9a
Autor:
Xiaoyun Tang, Christopher R. Cromwell, Rongzong Liu, Roseline Godbout, Basil P. Hubbard, Todd P.W. McMullen, David N. Brindley
Publikováno v:
Theranostics. 12(13)
LPP2 is one of three enzymes in the lipid phosphate phosphatase family (LPP1-3) that dephosphorylate extracellular and intracellular bioactive lipid phosphates and pyrophosphates. LPP2 increases cell growth and LPP2 expression is elevated in a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fb2c2ecf06cc9edc197e70606a2bf0
https://pubmed.ncbi.nlm.nih.gov/35966578
https://pubmed.ncbi.nlm.nih.gov/35966578