Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Todd P. W. McMullen"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9817 (2021)
Human cytomegalovirus (HCMV) infects 40–70% of adults in developed countries. HCMV proteins and DNA are detected in tumors and metastases, suggesting an association with increased invasion. We investigated HCMV infection in human breast cancer cell
Externí odkaz:
https://doaj.org/article/c917711f5f9f4e8d989320ff94c5a23d
Autor:
Frank Wuest, Melinda Wuest, David N. Brindley, Todd P. W. McMullen, Marcus Litchfield, Daryl Glubrecht, Emmanuelle Briard, Yves Auberson
Publikováno v:
Molecular Pharmaceutics. 18:3352-3364
Autotaxin (ATX) is a secreted enzyme responsible for producing lysophosphatidic acid (LPA). The ATX/LPA signaling axis is typically activated in wound healing and tissue repair processes. The ATX/LPA axis is highjacked and upregulated in the progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ef2a3e5492b5498543722442b45f05
https://doi.org/10.1021/acs.molpharmaceut.1c00265
https://doi.org/10.1021/acs.molpharmaceut.1c00265
Autor:
Ana Anoveros-Barrera, Oliver F. Bathe, David L. Bigam, Amritpal S. Bhullar, Todd P. W. McMullen, Michael T. Clandinin, Vera C. Mazurak, Vickie E. Baracos, Irma Magaly Rivas-Serna, Abha R. Dunichand-Hoedl, Rachel G. Khadaroo, Charles T. Putman
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Emerging studies are reporting associations between skeletal muscle abnormalities and survival in cancer patients. Cancer prognosis is associated with depletion of essential fatty acids in erythrocytes and plasma in humans. However the relationship b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794a7992ea105710b7832bc359381d9c
http://europepmc.org/articles/PMC8626431
http://europepmc.org/articles/PMC8626431
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9817, p 9817 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences
Volume 22
Issue 18
Human cytomegalovirus (HCMV) infects 40–70% of adults in developed countries. HCMV proteins and DNA are detected in tumors and metastases, suggesting an association with increased invasion. We investigated HCMV infection in human breast cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a6eb9fe24f695784f4315560bc20df
https://www.mdpi.com/1422-0067/22/18/9817
https://www.mdpi.com/1422-0067/22/18/9817
Autor:
Marcus, Litchfield, Melinda, Wuest, Daryl, Glubrecht, Emmanuelle, Briard, Yves P, Auberson, Todd P W, McMullen, David N, Brindley, Frank, Wuest
Publikováno v:
Molecular pharmaceutics. 18(9)
Autotaxin (ATX) is a secreted enzyme responsible for producing lysophosphatidic acid (LPA). The ATX/LPA signaling axis is typically activated in wound healing and tissue repair processes. The ATX/LPA axis is highjacked and upregulated in the progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b3c6e97de08c4cf2c1da90a982f6aed
https://pubmed.ncbi.nlm.nih.gov/34319110
https://pubmed.ncbi.nlm.nih.gov/34319110
Autor:
Amritpal S. Bhullar, Abha R. Dunichand-Hoedl, Ana Anoveros-Barrera, Oliver F Bathe, Vera C. Mazurak, Charles T. Putman, Michael T. Clandinin, Rachel G. Khadaroo, Vickie E. Baracos, David L. Bigam, Todd P. W. McMullen, Irma Magaly Rivas-Serna
Background: Emerging studies are reporting associations between skeletal muscle abnormalities and survival in cancer patients. Cancer prognosis is associated with depletion of essential fatty acids in membrane of blood plasma and serum in humans, how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2138a0241c94a61c3f12b3ce7c48335b
https://doi.org/10.21203/rs.3.rs-310922/v1
https://doi.org/10.21203/rs.3.rs-310922/v1
Autor:
Fahed A Elian, David N. Brindley, Paulo Nuin, Todd P. W. McMullen, Sunita Ghosh, Tim Footz, Ubah Are, Michael A. Walter
Publikováno v:
Breast Cancer : Targets and Therapy
Fahed A Elian,1 Ubah Are,1 Sunita Ghosh,2,3 Paulo Nuin,1 Tim Footz,1 Todd PW McMullen,4 David N Brindley,5,6 Michael A Walter1 1Department of Medical Genetics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; 2Departmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82757338a2ccb4cc51477629edb5356c
https://www.dovepress.com/foxq1-is-differentially-expressed-across-breast-cancer-subtypes-with-l-peer-reviewed-article-BCTT
https://www.dovepress.com/foxq1-is-differentially-expressed-across-breast-cancer-subtypes-with-l-peer-reviewed-article-BCTT
Autor:
Ana Lopez-Campistrous, Hans-Soenke Jans, Jennifer Dufour, Frank Wuest, Melinda Wuest, Todd P. W. McMullen, Michael Wagner, Darryl D. Glubrecht
Publikováno v:
Endocrine-related cancer. 27(9)
Targeted therapy is increasingly used to manage metastatic papillary thyroid cancer. The focus of the present study was to examine glucose metabolism and tumor responses for thyroid cancer xenografts expressing the glycolytic pathway modulators plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0b7ab0427c5366f02e93fb1c03c0f9
https://pubmed.ncbi.nlm.nih.gov/32590338
https://pubmed.ncbi.nlm.nih.gov/32590338
Autor:
Zelei Yang, Xiaoyun Tang, Maria Eloisa Hasing, Xiaoli Pang, Sunita Ghosh, Todd P. W. McMullen, David N. Brindley, Denise G. Hemmings
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1148
Human cytomegalovirus (HCMV) infects 40–70% of adults in developed countries. Detection of HCMV DNA and/or proteins in breast tumors varies considerably, ranging from 0–100%. In this study, nested PCR to detect HCMV glycoprotein B (gB) DNA in bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f113bf57d6fd92f91532807d76681264
https://doi.org/10.3390/cancers14051148
https://doi.org/10.3390/cancers14051148
Autor:
David N. Brindley, Jonathan M. Curtis, Todd P. W. McMullen, Zelei Yang, Guanmin Meng, Xiaoyun Tang, Yuan-Yuan Zhao
Publikováno v:
The FASEB Journal. 33:1899-1910
Lysophosphatidate (LPA) signaling through 6 receptors is regulated by the balance of LPA production by autotaxin (ATX) vs. LPA degradation by lipid phosphate phosphatases (LPPs). LPA promotes an inflammatory cycle by increasing the synthesis of cyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3606ed260386edb4926f016cb7b5570
https://doi.org/10.1096/fj.201801226r
https://doi.org/10.1096/fj.201801226r