Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Todd P. Hansen"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:327-336
The identification of agents with antiproliferative activity against endothelial cells has significant value for the treatment of many angiogenesis-dependent pathologies. Herein, we describe the discovery of a series of thalidomide analogues possessi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c6cd36ec00ac20f8aa036b26f01627
https://doi.org/10.1016/j.bmc.2003.11.007
https://doi.org/10.1016/j.bmc.2003.11.007
Autor:
Owen B. McManus, Yali Kong, Sivanesan Dakshanamurthy, Wladek Minor, Ellen C. Merrick, Maksymilian Chruszcz, Todd P. Hansen, Brande S. Williams, Gary C. Davis, Kan Wang, Simeng Suy, Antoinette Cordova, Milton L. Brown, Manoj K. Patel, Zhang Li, Mikell Paige
Voltage-gated sodium channels are known to be expressed in neurons and other excitable cells. Recently, voltage-gated sodium channels have been found to be expressed in human prostate cancer cells. α-Hydroxy-α-phenylamides are a new class of small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f9de8f7fde14a318dc5bd1592b6c3b
https://europepmc.org/articles/PMC4111568/
https://europepmc.org/articles/PMC4111568/
Autor:
James D, Anderson, Todd P, Hansen, Paul W, Lenkowski, Alison M, Walls, Indrani M, Choudhury, Hilary A, Schenck, Mati, Friehling, Genevieve M, Höll, Manoj K, Patel, Robert A, Sikes, Milton L, Brown
Publikováno v:
Molecular cancer therapeutics. 2(11)
The recent discovery of sodium (Na(+)) channel expression in human prostate cancer (PCa) cells led us to investigate the potential use of neuronal Na(+) channel blockers as inhibitors of PCa cells. Our initial studies discovered two classes of Na(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::166c95f10d8339ddbbe4fe118679c1f4
https://pubmed.ncbi.nlm.nih.gov/14617788
https://pubmed.ncbi.nlm.nih.gov/14617788
Publikováno v:
Organic letters. 5(16)
[reaction: see text] A five-step synthesis of an azido-thalidomide analogue is presented. The sequence requires cheap and readily available starting materials and reagents, and only two steps require purification. Additionally, the azido-labeled anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaab64b2e5d11924fac9546bbac83488
https://pubmed.ncbi.nlm.nih.gov/12889894
https://pubmed.ncbi.nlm.nih.gov/12889894