Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Todd M. Przybycien"'
Autor:
Reilly McCracken, Noor Al-Nazal, Travis Whitmer, Sijia Yi, James M. Wagner, Colin G. Hebert, Matthew J. Lowry, Peter R. Hayes, James W. Schneider, Todd M. Przybycien, Malini Mukherjee
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1589 (2022)
Vaccinations to prevent infectious diseases are given to target the body’s innate and adaptive immune systems. In most cases, the potency of a live virus vaccine (LVV) is the most critical measurement of efficacy, though in some cases the quantity
Externí odkaz:
https://doaj.org/article/c1cb80f7b8c141b6a031515fb76fa7f2
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(1)
Adventitious agent testing in biomanufacturing requires assays of broad detection capability in order to screen for as many infectious agents as possible. The current gold standard for general infectious adventitious virus screening is the in vitro a
Publikováno v:
Biotechnology progressREFERENCES. 37(1)
Precipitation can be used for the initial purification of monoclonal antibodies (mAbs), with the soluble host cell proteins removed in the permeate by tangential flow microfiltration. The objective of this study was to examine the use of a feed-and-b
Publikováno v:
Biotechnology progressREFERENCES. 36(6)
As upstream product titers increase, the downstream chromatographic capture step has become a significant "downstream bottleneck." Precipitation becomes more attractive under these conditions as the supersaturation driving force increases with the ev
Autor:
Steven V. Iasella, Amy Z. Stetten, Robert D. Tilton, Todd M. Przybycien, Stephen Garoff, Timothy E. Corcoran
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 31:212-220
Background: Secondary lung infections are the primary cause of morbidity associated with cystic fibrosis lung disease. Aerosolized antibiotic inhalation is potentially advantageous but has limited effectiveness due to altered airway aerodynamics and
Publikováno v:
Journal of Environmental Chemical Engineering. 6:4564-4572
Cationic proteins from Moringa oleifera seeds are of interest as sustainable coagulants for drinking water treatment in regions with poor access to potable water. They have been shown to reduce turbidity in natural water sources as well as in various
Autor:
Timothy E. Corcoran, Robert D. Tilton, Todd M. Przybycien, Stephen Garoff, Bradley W. Treece, Amy Z. Stetten
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 546:266-275
Traditionally, an interface is defined as a boundary between immiscible phases. However, previous work has shown that even when two fluids are completely miscible, they maintain a detectable “effective interface” for long times. Miscible interfac
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 521:49-60
Marangoni flows offer an interesting and useful means to transport particles at fluid interfaces with potential applications such as dry powder pulmonary drug delivery. In this article, we investigate the transport of partially wetted particles at a
Publikováno v:
Journal of Environmental Chemical Engineering. 4:4690-4698
Extracts containing cationic proteins from Moringa oleifera seeds are used to reduce drinking water turbidity in developing regions where the plant grows. To identify the active components in the seed extract, high performance liquid chromatography w
Publikováno v:
Biotechnology Progress. 35
There is renewed interest in the possibility of using precipitation for initial capture of high-value therapeutic proteins as part of an integrated continuous downstream process. Precipitation is greatly facilitated by the high product titers now ach