Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Todd M. Maddux"'
Publikováno v:
Synthetic Communications. 30:1221-1226
The use of diisopropylcarbodiimide as an agent to effect the coupling of carboxylic acids to Evans' chiral auxiliary (4R, 5S)-4-methyl-5-phenyl-2-oxazolidinone provides the corresponding acyl derivatives in good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::648a906d2ecdc56cf4420f2e5c15d59a
https://doi.org/10.1080/00397910008087142
https://doi.org/10.1080/00397910008087142
Publikováno v:
ChemInform. 31
The use of diisopropylcarbodiimide as an agent to effect the coupling of carboxylic acids to Evans' chiral auxiliary (4R, 5S)-4-methyl-5-phenyl-2-oxazolidinone provides the corresponding acyl derivatives in good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::212827087cd4e32cd939188b0979f378
https://doi.org/10.1002/chin.200033122
https://doi.org/10.1002/chin.200033122
Autor:
Robert O, Hughes, D Joseph, Rogier, E Jon, Jacobsen, John K, Walker, Alan, Macinnes, Brian R, Bond, Lena L, Zhang, Ying, Yu, Yi, Zheng, Jeanne M, Rumsey, Jennie L, Walgren, Sandra W, Curtiss, Yvette M, Fobian, Steven E, Heasley, Jerry W, Cubbage, Joseph B, Moon, David L, Brown, Brad A, Acker, Todd M, Maddux, Mike B, Tollefson, Brent V, Mischke, Dafydd R, Owen, John N, Freskos, John M, Molyneaux, Alan G, Benson, Rhadika M, Blevis-Bal
Publikováno v:
Journal of medicinal chemistry. 53(6)
We recently described a novel series of aminopyridopyrazinones as PDE5 inhibitors. Efforts toward optimization of this series culminated in the identification of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88c2de53db53a1f8525bbef66ae6a7e3
https://pubmed.ncbi.nlm.nih.gov/20196613
https://pubmed.ncbi.nlm.nih.gov/20196613