Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Todd M. Lasner"'
Autor:
Sylvain Palmer, In Ki Mun, Allen B. Kantrowitz, Stan G. Shalayev, Gregory S. Mallek, Allan D. Levi, Todd M. Lasner
Publikováno v:
Neurosurgical Focus. 16:1-4
The authors present an in-depth retrospective analysis of retractor systems for anterior odontoid screw fixation. They discuss various modifications and innovations of such systems and describe their own tubular retractor system, in which a beveled e
Autor:
Nigel W. Fraser, Aikaterini Skokotas, Jeffry J. Leary, Todd M. Lasner, Ruth Tal-Singer, Shelley L. Berger, Wawrzyniec Podrzucki
Publikováno v:
Journal of Virology. 72:1252-1261
The detailed mechanism which governs the choice between herpes simplex virus (HSV) latency and reactivation remains to be elucidated. It is probable that altered expression of cellular factors in sensory neurons leads to induction of HSV gene express
Publikováno v:
Pediatric Neurosurgery. 27:50-55
Autor:
Todd M. Lasner, Santosh Kesari, Nigel W. Fraser, Ruth Tal-Singer, John Q. Trojanowski, Virginia M.-Y. Lee
Publikováno v:
Journal of neurovirology. 4(1)
HSV-1 mutants in the RL-1 gene encoding the ICP34.5 protein have been demonstrated to have diminished neurovirulence in brain yet replicate as efficiently as parental virus in transformed tissue culture cells. Thus they have been proposed as candidat
Autor:
Robert W. Hurst, Eugene S. Flamm, Todd M. Lasner, Joseph T. King, Eric L. Zager, David J. Langer
Publikováno v:
Neurosurgery. 42(3)
OBJECTIVE: To identify clinical and angiographic factors of cerebral arteriovenous malformations (AVMs) associated with hemorrhage to improve the estimation of the risks and help guide management in clinical decision making. METHODS: We conducted a r
Autor:
Virginia M.-Y. Lee, K. R. Balsara, Santosh Kesari, Bruce Randazzo, John Q. Trojanowski, Todd M. Lasner, Nigel W. Fraser
Publikováno v:
The Journal of general virology. 79
Herpes simplex virus type 1 (HSV-1) variant 1716 is deleted in the gene encoding ICP34.5 and is neuroattenuated after intracranial inoculation of mice. Although the mechanism of attenuation is unclear, this property has been exploited to eliminate ex
Autor:
Todd M. Lasner, J. W. Trojanowski, Virginia M.-Y. Lee, Nigel W. Fraser, Santosh Kesari, S. M. Brown
Publikováno v:
Journal of neuropathology and experimental neurology. 55(12)
To develop improved therapies for medulloblastoma, we studied the ability of a neuroattenuated HSV-1 ICP34.5 mutant (variant-1716) to replicate within and destory an authentic medulloblastoma cell line known as Med 283 (D283) using immunohistochemist
Publikováno v:
Journal of neurosurgery. 81(1)
✓ Recent reports of seven cases of Lhermitte-Duclos disease occurring in adult patients with Cowden's syndrome (multiple hamartoma syndrome) strongly suggest that Lhermitte-Duclos disease is one of the types of neoplasia that characterize this synd
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 55:623
Autor:
Nigel W. Fraser, Bruce Randazzo, John Q. Trojanowski, Eugene Chung, Todd M. Lasner, Rath Pichyangkura, Ruth Tal-Singer, Steven J. Triezenberg
Publikováno v:
Virology. (1):20-33
The herpes simplex virus (HSV) transactivator VP16 is a structural component of the virion that activates immediate-early viral gene expression. The HSV-1 mutant in1814, which contains a 12-bp insertion that compromises the transcriptional function o