Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Todd L. Mollan"'
Autor:
John S. Olson, Abdu I. Alayash, Wayne Hicks, Tigist Kassa, Michael Brad Strader, Eileen W. Singleton, Michael T. Wilson, Todd L. Mollan, Mitchell J. Weiss, Jayashree Soman
Publikováno v:
Journal of Biological Chemistry. 289:22342-22357
A pathogenic V67M mutation occurs at the E11 helical position within the heme pockets of variant human fetal and adult hemoglobins (Hb). Subsequent post-translational modification of Met to Asp was reported in γ subunits of human fetal Hb Toms River
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2655b57104e4ddf127b17ea6d056cfa4
https://doi.org/10.1074/jbc.m114.568980
https://doi.org/10.1074/jbc.m114.568980
Autor:
Yiping Jia, Sambuddha Banerjee, Gang Wu, R. Timothy Kreulen, John S. Olson, Ah-Lim Tsai, Alvin L. Crumbliss, Todd L. Mollan, Abdu I. Alayash
Publikováno v:
Free Radical Biology and Medicine. 69:265-277
Haptoglobin (Hp) is an abundant and conserved plasma glycoprotein, which binds acellular adult hemoglobin (Hb) dimers with high affinity and facilitates their rapid clearance from circulation after hemolysis. Humans possess three main phenotypes of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad1f3d7af44d47d24a08cff7cd4301c
https://doi.org/10.1016/j.freeradbiomed.2014.01.030
https://doi.org/10.1016/j.freeradbiomed.2014.01.030
Autor:
Eugene Khandros, Joel P. Mackay, Claire F. Dickson, Todd L. Mollan, John S. Olson, Peter A. Lay, Anne M. Rich, Jason A. Lowry, W. d’Avigdor, Daniel A. T. Collins, Mitchell J. Weiss, David A. Gell
Publikováno v:
Journal of Biological Chemistry. 288:19986-20001
α-Hemoglobin (αHb)-stabilizing protein (AHSP) is a molecular chaperone that assists hemoglobin assembly. AHSP induces changes in αHb heme coordination, but how these changes are facilitated by interactions at the αHb·AHSP interface is not well u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad55ff5a7e4d814e5f1fb6c9d1281c3f
https://doi.org/10.1074/jbc.m112.437509
https://doi.org/10.1074/jbc.m112.437509
Autor:
Ivan Birukou, Todd L. Mollan, Bryan J.Z. Smith, Cornelius L. Varnado, Douglas P. Henderson, John S. Olson
Publikováno v:
Antioxidants & Redox Signaling. 18:2314-2328
Significance: The worldwide blood shortage has generated a significant demand for alternatives to whole blood and packed red blood cells for use in transfusion therapy. One such alternative involves the use of acellular recombinant hemoglobin (Hb) as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b15d022db00cd0b159473f64c6778d
https://doi.org/10.1089/ars.2012.4917
https://doi.org/10.1089/ars.2012.4917
Autor:
John S. Olson, Jay N. Lozier, Michael Brad Strader, Abdu I. Alayash, Yiping Jia, Todd L. Mollan, Bindu Abraham
Publikováno v:
Protein Science. 21:1444-1455
Hemoglobin Brigham (β Pro100 to Leu) was first reported in a patient with familial erythrocytosis. Erythrocytes of an affected individual from the same family contain both HbA and Hb Brigham and exhibit elevated O2 affinity compared with normal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb75910a5e3c0afa186886a11019541
https://doi.org/10.1002/pro.2130
https://doi.org/10.1002/pro.2130
Publikováno v:
Blood. 113:5961-5969
Alpha hemoglobin stabilizing protein (AHSP) reversibly binds nascent α globin to maintain its native structure and facilitate its incorporation into hemoglobin A. Previous studies indicate that some naturally occurring human α globin mutations may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598716a34a3c351a119066c5789e9721
https://doi.org/10.1182/blood-2008-12-196030
https://doi.org/10.1182/blood-2008-12-196030
Autor:
Michael Brad, Strader, Wayne A, Hicks, Tigist, Kassa, Eileen, Singleton, Jayashree, Soman, John S, Olson, Mitchell J, Weiss, Todd L, Mollan, Michael T, Wilson, Abdu I, Alayash
Publikováno v:
The Journal of biological chemistry. 289(32)
A pathogenic V67M mutation occurs at the E11 helical position within the heme pockets of variant human fetal and adult hemoglobins (Hb). Subsequent post-translational modification of Met to Asp was reported in γ subunits of human fetal Hb Toms River
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9759d02e82cd8628fb5fe45f9256ba0d
https://pubmed.ncbi.nlm.nih.gov/24939847
https://pubmed.ncbi.nlm.nih.gov/24939847
Autor:
Mitchell J. Weiss, Todd L. Mollan, Abdu I. Alayash, Claire J. Parker Siburt, Sambuddha Banerjee, Gang Wu, John S. Olson, Ah-Lim Tsai, Alvin L. Crumbliss
Publikováno v:
The Journal of biological chemistry. 288(6)
α-Hemoglobin stabilizing protein (AHSP) is a molecular chaperone that binds monomeric α-subunits of human hemoglobin A (HbA) and modulates heme iron oxidation and subunit folding states. Although AHSP·αHb complexes autoxidize more rapidly than Hb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d60767601869e8b91bfff8fcd1cc65
https://pubmed.ncbi.nlm.nih.gov/23264625
https://pubmed.ncbi.nlm.nih.gov/23264625
Autor:
Todd L, Mollan, Bindu, Abraham, Michael Brad, Strader, Yiping, Jia, Jay N, Lozier, John S, Olson, Abdu I, Alayash
Publikováno v:
Protein science : a publication of the Protein Society. 21(10)
Hemoglobin Brigham (β Pro100 to Leu) was first reported in a patient with familial erythrocytosis. Erythrocytes of an affected individual from the same family contain both HbA and Hb Brigham and exhibit elevated O2 affinity compared with normal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15c0d4e70ea91b6f7ac0c059c8a798e0
https://pubmed.ncbi.nlm.nih.gov/22821886
https://pubmed.ncbi.nlm.nih.gov/22821886
Human α-hemoglobin stabilizing protein (AHSP) is a conserved mammalian erythroid protein that facilitates the production of Hemoglobin A by stabilizing free α-globin. AHSP rapidly binds to ferrous α with association (k'(AHSP)) and dissociation (k(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05af8742ca6e84efa0b8310bbf0572c4
https://europepmc.org/articles/PMC3322864/
https://europepmc.org/articles/PMC3322864/
