Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Todd J Zurlinden"'
Autor:
Dustin F Kapraun, Todd J Zurlinden, Marc-André Verner, Catheryne Chiang, Michael W Dzierlenga, Laura M Carlson, Paul M Schlosser, Geniece M Lehmann
Publikováno v:
Toxicological Sciences. 189:155-174
Lipophilic persistent environmental chemicals (LPECs) can accumulate in a woman’s body and transfer to her developing child across the placenta and via breast milk. To assess health risks associated with developmental exposures to LPECs, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d52c303335516293ad3f1480175c0cc
https://doi.org/10.1093/toxsci/kfac084
https://doi.org/10.1093/toxsci/kfac084
Autor:
Anne H. Chappelle, Kimberly W. White, Donna L. Mendrick, Linda S. Birnbaum, Laurie C. Haws, Suzanne Fitzpatrick, K. Nadira De Abrew, Katerine S. Saili, Jill A Franzosa, Thomas B. Knudsen, Susan Y. Euling, Alison Elder, George P. Daston, Nicole Kleinstreuer, Alexandra Turley, Ruthann A. Rudel, Dana C. Dolinoy, Elaine M. Faustman, Germaine M. Buck Louis, Thaddeus T. Schug, Todd J. Zurlinden, Robyn L Tanguay, Barbara A. Wetmore, Derik E. Haggard, Kristi Pullen Fedinick
Publikováno v:
Toxicol Sci
FutureTox IV, a Society of Toxicology Contemporary Concepts in Toxicology workshop, was held in November 2018. Building upon FutureTox I, II, and III, this conference focused on the latest science and technology for in vitro profiling and in silico m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310085fc00705890b8369a9c0dbe4576
https://doi.org/10.1093/toxsci/kfab013
https://doi.org/10.1093/toxsci/kfab013
Autor:
Todd J. Zurlinden, Chad Deisenroth, Russell S. Thomas, Mi-Young Lee, Paul L. Carmichael, Danica E DeGroot, James McCord, Andrew Eicher
Publikováno v:
Toxicol Sci
The U.S. EPA Endocrine Disruptor Screening Program utilizes data across the ToxCast/Tox21 high-throughput screening (HTS) programs to evaluate the biological effects of potential endocrine active substances. A potential limitation to the use of in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560b1ac8cd0e1a44db6541cedc5db87b
https://doi.org/10.1093/toxsci/kfaa147
https://doi.org/10.1093/toxsci/kfaa147
Autor:
Thomas B. Knudsen, Tarja Toimela, Todd J. Zurlinden, Nancy C. Baker, Katerine S. Saili, Tuula Heinonen
Publikováno v:
Reprod Toxicol
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately results in formation of the blood-brain barrier. Typical high-throughput screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ece6d959a96aa1ef8cc8685dfad9d9f
https://doi.org/10.1016/j.reprotox.2020.06.010
https://doi.org/10.1016/j.reprotox.2020.06.010
Autor:
Chelsea A. Weitekamp, Drake Phelps, Tamara Tal, Tara R. Catron, Emily Wheaton, Todd J. Zurlinden, Charles E. Wood, Nichole E. Brinkman, Scott P. Keely, Jon R. Sobus, Mark J. Strynar, Charlene A. McQueen, James McCord, Adam Swank
Publikováno v:
Toxicological Sciences. 172:109-122
Microbiota regulate important physiologic processes during early host development. They also biotransform xenobiotics and serve as key intermediaries for chemical exposure. Antimicrobial agents in the environment may disrupt these complex interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f9c4f58462bc8d937869aff5d330b0e
https://doi.org/10.1093/toxsci/kfz166
https://doi.org/10.1093/toxsci/kfz166
Autor:
Menghang Xia, Robert G. Ellis-Hutchings, Jill A Franzosa, Nancy C. Baker, Edward W. Carney, Todd J. Zurlinden, Raja S. Settivari, Thomas B. Knudsen, Richard M. Spencer, Katerine S. Saili, Nicole Kleinstreuer, Shuaizhang Li
Publikováno v:
Curr Opin Toxicol
The more than 80,000 chemicals in commerce present a challenge for hazard assessments that toxicity testing in the 21(st) century strives to address through high-throughput screening (HTS) assays. Assessing chemical effects on human development adds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cde42be6e0dcaccb490d07266d4eca8
https://doi.org/10.1016/j.cotox.2019.04.004
https://doi.org/10.1016/j.cotox.2019.04.004
Autor:
Tara R. Catron, Todd J. Zurlinden, Scott P. Keely, Allison Kvasnicka, Chelsea A. Weitekamp, Xia Meng Howey, Emily Wheaton, Tamara Tal, Nichole E. Brinkman, Drake Phelps, Shaza Gaballah
Publikováno v:
Animal Microbiome
Animal Microbiome, Vol 3, Iss 1, Pp 1-13 (2021)
Animal Microbiome, Vol 3, Iss 1, Pp 1-13 (2021)
Background Across taxa, animals with depleted intestinal microbiomes show disrupted behavioral phenotypes. Axenic (i.e., microbe-free) mice, zebrafish, and fruit flies exhibit increased locomotor behavior, or hyperactivity. The mechanism through whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371128e9b81273ba08dc5e131358c8e4
https://doi.org/10.1186/s42523-020-00069-x
https://doi.org/10.1186/s42523-020-00069-x
Autor:
Parth Kothiya, Katerine S. Saili, Todd J. Zurlinden, Nathaniel Rush, Jessica A. Palmer, Thomas B. Knudsen, Nancy C. Baker, Russell S. Thomas, E. Sidney Hunter, Keith A. Houck, Richard S. Judson
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 177(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593b74df75221c8169d3073bff47cb51
https://pubmed.ncbi.nlm.nih.gov/32529217
https://pubmed.ncbi.nlm.nih.gov/32529217
Autor:
Katerine S. Saili, Nathaniel Rush, Parth Kothiya, Nancy C. Baker, Keith A. Houck, Jessica A. Palmer, Thomas B. Knudsen, Russell S. Thomas, E. Sidney Hunter, Todd J. Zurlinden, Richard S. Judson
Publikováno v:
Toxicol Sci
The Stemina devTOX quickPredict platform is a human pluripotent stem cell-based assay that predicts the developmental toxicity potential based on changes in cellular metabolism following chemical exposure [Palmer, J. A., Smith, A. M., Egnash, L. A.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b91565f18d67de5e439b850a5e47f6c
https://europepmc.org/articles/PMC8527599/
https://europepmc.org/articles/PMC8527599/
Autor:
Tara R. Catron, Emily Wheaton, Todd J. Zurlinden, Drake Phelps, Nichole E. Brinkman, Shaza Gaballah, Charles E. Wood, Scott P. Keely, Tamara Tal, Allison Kvasnicka, Regina Lamendella, Justin P. Wright
Publikováno v:
Toxicological Sciences. 167:468-483
Host-associated microbiota can biotransform xenobiotics, mediate health effects of chemical exposure, and play important roles in early development. Bisphenol A (BPA) is a widespread environmental chemical that has been associated with adverse endocr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338fc4f68c3fa20d292be82bd3c0a4f8
https://doi.org/10.1093/toxsci/kfy261
https://doi.org/10.1093/toxsci/kfy261