Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease

Autor: Alfred H. Merrill, Jr., Todd H. Stokes, Amin Momin, Hyejung Park, Brent J. Portz, Samuel Kelly, Elaine Wang, M. Cameron Sullards, May Dongmei Wang

Publikováno v: Journal of Lipid Research, Vol 50, Iss , Pp S97-S102 (2009)

The sphingolipidome is the portion of the lipidome that encompasses all sphingoid bases and their derivatives. Whereas the most studied sphingoid base is sphingosine [(2S,3R,4E)-2-aminooctadecene-1,3-diol], mammals have dozens of structural variants,

Externí odkaz: https://doaj.org/article/afc13dd991ce4706a9114fdd7d58d96c

Semiconductor Quantum Dots for Bioimaging and Biodiagnostic Applications

Autor: Brad A. Kairdolf, Todd H. Stokes, Andrew M. Smith, Andrew N. Young, May D. Wang, Shuming Nie

Publikováno v: Annual Review of Analytical Chemistry. 6:143-162

Semiconductor quantum dots (QDs) are light-emitting particles on the nanometer scale that have emerged as a new class of fluorescent labels for chemical analysis, molecular imaging, and biomedical diagnostics. Compared with traditional fluorescent pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06909f08e71b6fc2e11a6b103d32e07f
https://doi.org/10.1146/annurev-anchem-060908-155136

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Autor: Zhichao Liu, Shujian Wu, Reena Philip, Roderick V. Jensen, Xiao Zeng, Frank W. Samuelson, Wendy Czika, Gene Pennello, Fathi Elloumi, Frank Westermann, Matthew N. McCall, James C. Fuscoe, Yichao Wu, Mauro Delorenzi, Bart Barlogie, Nina Gonzaludo, Li Li, Joel S. Parker, Rong Chen, Zivana Tezak, Jianping Wu, Rafael A. Irizarry, Xijin Ge, Andreas Scherer, Xuejun Peng, Joshua Xu, Stephanie Fulmer-Smentek, Feng Qian, Giuseppe Jurman, Xuegong Zhang, Huixiao Hong, Richard A. Moffitt, Zhen Li, Yiming Zhou, Roberto Visintainer, Dilafruz Juraeva, Damir Herman, Joaquín Dopazo, Federico Goodsaid, Zhenqiang Su, Weiwei Shi, Chang Chang, Aaron Smalter, Mark R. Fielden, Alan H. Roter, Yvonne Kahlert, Junwei Wang, Shao Li, Pierre R. Bushel, Jianying Li, Yiyu Cheng, Matthias Kohl, David Montaner, Darlene R. Goldstein, Qian Xie, Raj K. Puri, Chen Zhao, Richard J. Brennan, Li Zheng, Menglong Li, Anne Bergstrom Lucas, Jun Huan, Zhiguang Li, Jing Han, Brandon D. Gallas, Guozhen Liu, Matthew Woods, Kevin C. Dorff, Danielle Thierry-Mieg, Xiaohui Fan, Wenjun Bao, Lakshmi Vishnuvajjala, Qinglan Sun, George Mulligan, Pan Du, Sadik A. Khuder, Christos Sotiriou, Xutao Deng, John Zhang, Jie Cheng, Charles Wang, Marina Tsyganova, Leming Shi, Sue Jane Wang, Kenneth R. Hess, Nianqing Xiao, Jennifer G. Catalano, Russell S. Thomas, Rong Tang, Frank Staedtler, Wen Luo, David J. Dix, Benedikt Brors, Juergen Von Frese, W. Fraser Symmans, Yang Feng, Lu Meng, Samantha Riccadonna, Gregory Campbell, Charles D. Johnson, John H. Phan, Johan Trygg, Ron L. Peterson, Sheng Zhu, Jie Liu, May D. Wang, Dhivya Arasappan, John D. Shaughnessy, R. Mitchell Parry, Tatiana Nikolskaya, Youping Deng, Stephen C. Harris, Tieliu Shi, Manuel Madera, Jeff W. Chou, Grier P. Page, Baitang Ning, Jian Cui, Liang Zhang, Eric Wang, Russell D. Wolfinger, Venkata Thodima, J. Luo, Min Zhang, Timothy Davison, Sheng Zhong, Guido Steiner, Pei Yi Tan, Yi Ren, Frank Berthold, Padraic Neville, Viswanath Devanarayan, Yaron Turpaz, Ying Liu, Uwe Scherf, Jialu Zhang, Lei Xu, Jennifer Fostel, Shengzhu Si, Christophe G. Lambert, Jianqing Fan, Yanen Li, Rui Jiang, Cesare Furlanello, Zhining Wen, Jianping Huang, Lajos Pusztai, Li Lee, Mat Soukup, Brett T. Thorn, Joseph D. Shambaugh, Hong Fang, S. Vega, Andreas Buness, Todd H. Stokes, Christos Hatzis, Waleed A. Yousef, Lun Yang, Francesca Demichelis, Nathan D. Price, Donald N. Halbert, Qiang Shi, Ignacio Medina, Martin Schumacher, Stephen J. Walker, Wendell D. Jones, Fabien Campagne, Li Guo, James C. Willey, Joseph Meehan, Weigong Ge, Hans Bitter, Max Bylesjö, Jing Cheng, Matthias Fischer, Richard S. Paules, Piali Mukherjee, Jean Thierry-Mieg, Laurent Gatto, Shicai Fan, Roland Eils, Tzu Ming Chu, Yuri Nikolsky, Brian Quanz, André Oberthuer, Simon Lin, Francisco Martinez-Murillo, Damir Dosymbekov, Jaeyun Sung, Minjun Chen, Richard Shippy, Samir Lababidi, Edward K. Lobenhofer, Vlad Popovici, Weida Tong, Quan Zhen Li, Dalila B. Megherbi, Roger Perkins, Wei Wang, K. Miclaus, Richard S. Judson, Weijie Chen

Publikováno v: Nature Biotechnology. 28:827-838

Gene expression data from microarrays are being applied to predict preclinical and clinical endpoints, but the reliability of these predictions has not been established. In the MAQC-II project, 36 independent teams analyzed six microarray data sets t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6806d05f1d68b258ce11317a2537a21f
https://doi.org/10.1038/nbt.1665

Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment

Autor: Todd H. Stokes, Andrew N. Young, John H. Phan, May D. Wang, Jian Liu, Shuming Nie, Richard A. Moffitt

Publikováno v: Trends in Biotechnology. 27:350-358

Recent advances in biomarker discovery, biocomputing and nanotechnology have raised new opportunities in the emerging fields of personalized medicine (in which disease detection, diagnosis and therapy are tailored to each individual's molecular profi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2f8f200a8e1d31f50d3cf181721b86
https://doi.org/10.1016/j.tibtech.2009.02.010

Unmixing of spectrally similar quantum dots using filter selection

Autor: Todd H. Stokes, Elena N. Hubbard, May D. Wang, Jonathan K. Tran, Brad A. Kairdolf

Publikováno v: EMBC

This paper explores the possibilities for quantitative analysis of multiplexed Quantum Dot Immunohistochemical (QDIHC) staining using a 10-slot fluorescence microscope filter wheel. QDs are an ideal fluorophore for staining biomarkers due to their un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7118add1d3e869020f9f6226d7e7ee05
https://pubmed.ncbi.nlm.nih.gov/24110361