Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Todd G. Kroll"'
Supplementary Figure 1 from Peroxisome Proliferator-Activated Receptor-δ Induces Cell Proliferation by a Cyclin E1–Dependent Mechanism and Is Up-regulated in Thyroid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0069467f3705c448535202a72dc850
https://doi.org/10.1158/0008-5472.22375500
https://doi.org/10.1158/0008-5472.22375500
Peroxisome proliferator-activated receptors (PPARs) are lipid-sensing nuclear receptors that have been implicated in multiple physiologic processes including cancer. Here, we determine that PPARδ induces cell proliferation through a novel cyclin E1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc1bb4fdeed3e3e48d5b08b95728634
https://doi.org/10.1158/0008-5472.c.6497850
https://doi.org/10.1158/0008-5472.c.6497850
Autor:
Todd G. Kroll, Catharina Larsson, Anders Höög, Ulla Enberg, Barbara Leibiger, Ingo Leibiger, Edwin L. Kaplan, Maria Tretiakova, Seema Deshpande, Victoria Rehrmann, Lingchun Zeng, Weng-Onn Lui
Supplementary Figure 1 from CREB3L2-PPARγ Fusion Mutation Identifies a Thyroid Signaling Pathway Regulated by Intramembrane Proteolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c99a588295b35b6c711801a8614935a
https://doi.org/10.1158/0008-5472.22375596
https://doi.org/10.1158/0008-5472.22375596
Supplementary Figure 2 from Peroxisome Proliferator-Activated Receptor-δ Induces Cell Proliferation by a Cyclin E1–Dependent Mechanism and Is Up-regulated in Thyroid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8182fa488358590bf521f66170ab3484
https://doi.org/10.1158/0008-5472.22375497
https://doi.org/10.1158/0008-5472.22375497
Autor:
Maria S. Tretiakova, Masha Kocherginsky, Todd G. Kroll, Tracy K. Hale, David A. Wheeler, Alejandro Contreras, Sarah Bond
Publikováno v:
Laboratory Investigation. 94:788-795
Owing to the loss of heterochromatin integrity that occurs during thyroid tumorigenesis, the expression of Heterochromatin Protein 1 isoforms HP1α and HP1β was assessed by immunohistochemistry in 189 thyroid tumors and non-neoplastic tissues. Expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bc3087c0ffcdd1cb8358ed8512728f
https://doi.org/10.1038/labinvest.2014.68
https://doi.org/10.1038/labinvest.2014.68
Autor:
Vidya Nallasura, Ravi Salgia, Aliya N. Husain, Rajani Kanteti, Todd G. Kroll, Leonardo Faoro, Philip T. Cagle, Everett E. Vokes, Sivakumar Loganathan, Deborah Lang, Soundararajan Krishnaswamy, Maria Tretiakova
Publikováno v:
Laboratory Investigation. 89:301-314
PAX5 is a nuclear transcription factor required for B cell development, and its expression was evaluated in upper aerodigestive malignancies and pancreatic cancer by immunoblotting. The PAX5 protein expression was relatively strong in small-cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b346ad03552c96352d502563bc1c92
https://doi.org/10.1038/labinvest.2008.168
https://doi.org/10.1038/labinvest.2008.168
Autor:
Catharina Larsson, Victoria Rehrmann, Maria Tretiakova, Barbara Leibiger, Ingo B. Leibiger, Seema S. Deshpande, Lingchun Zeng, Ulla Enberg, Weng-Onn Lui, Todd G. Kroll, Anders Höög, Edwin L. Kaplan
Publikováno v:
Cancer Research. 68:7156-7164
The discovery of gene fusion mutations, particularly in leukemia, has consistently identified new cancer pathways and led to molecular diagnostic assays and molecular-targeted chemotherapies for cancer patients. Here, we report our discovery of a nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e199bef71a574ee4fae14ab2332efe3
https://doi.org/10.1158/0008-5472.can-08-1085
https://doi.org/10.1158/0008-5472.can-08-1085
Autor:
Seema S. Deshpande, Brandon L. Allard, Stefan K.G. Grebe, Xiao Li Wang, J. Gregory Powell, Todd G. Kroll, Xiying Wang, Mustafa Sahin, Bryan McIver, Norman L. Eberhardt, Ian D. Hay, Henry J. Hiddinga
Publikováno v:
Oncogene. 23:3634-3641
Follicular thyroid carcinoma (FTC) frequently harbors the PAX8/PPARgamma fusion gene (PPFP); however, its oncogenic role and mechanism(s) of action remain undefined. We investigated PPFP's effects on cell growth, apoptosis, cell-cell, and cell-matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646384046f74b8d57720ad8cb5ad81c1
https://doi.org/10.1038/sj.onc.1207399
https://doi.org/10.1038/sj.onc.1207399
Autor:
Todd G. Kroll
Publikováno v:
The American Journal of Pathology. 160:1941-1944
Tumor development within the human thyroid gland provides an attractive experimental model with which to consider the pathogenesis of carcinoma, the most common and clinically significant cancer. Thyroid tumors are readily accessible to morphological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3a163369aeef25cbbd3ba1c189d2efa
https://doi.org/10.1016/s0002-9440(10)61142-x
https://doi.org/10.1016/s0002-9440(10)61142-x
Autor:
Todd G. Kroll, Chang-Jie Chen, Elisabetta Mueller, Bruce M. Spiegelman, Lorenza Pecciarini, Pasha Sarraf, Jonathan A. Fletcher
Publikováno v:
Science. 289:1357-1360
Chromosomal translocations that encode fusion oncoproteins have been observed consistently in leukemias/lymphomas and sarcomas but not in carcinomas, the most common human cancers. Here, we report that t(2;3)(q13;p25), a translocation identified in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::308e62ebba8be5478cabcf6166db5131
https://doi.org/10.1126/science.289.5483.1357
https://doi.org/10.1126/science.289.5483.1357