Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Todd E. Meyerrose"'
Publikováno v:
BioTechniques, Vol 35, Iss 6, Pp 1262-1272 (2003)
The field of murine models of xenotransplantation has grown immensely over the past two decades. The explosive growth in this field is in part due to the fact that good in vitro methods do not exist yet to allow examination of human stem cell homing
Externí odkaz:
https://doaj.org/article/abd62bc88aa34437ad46f79e22c27086
Autor:
Scott D. Olson, Suzanne Pontow, Yunjoon Jung, Todd E. Meyerrose, Jan A. Nolta, Geralyn Annett, Gerhard Bauer, Stefanos Kalomoiris
Publikováno v:
Advanced Drug Delivery Reviews. 62:1167-1174
Mesenchymal stem cells (MSC) are a promising tool for cell therapy, either through direct contribution to the repair of bone, tendon and cartilage or as an adjunct therapy through protein production and immune mediation. They are an attractive vehicl
Autor:
Louisa Wirthlin, Carole Vogler, Todd E. Meyerrose, Kevin K. Ohlemiller, Marie S. Roberts, Jan A. Nolta, Mark S. Sands
Publikováno v:
Stem Cells. 26:1713-1722
Bone marrow-derived mesenchymal stem cells (MSCs) are a promising platform for cell- and gene-based treatment of inherited and acquired disorders. We recently showed that human MSCs distribute widely in a murine xenotransplantation model. In the curr
Autor:
Todd E. Meyerrose, Michael H. Creer, Kathryn C. Partlow, Shelton D. Caruthers, Gregory M. Lanza, Jason A. Brant, Samuel A. Wickline, Junjie Chen, Anne M. Neubauer, Jan A. Nolta
Publikováno v:
The FASEB Journal. 21:1647-1654
MRI has been employed to elucidate the migratory behavior of stem/progenitor cells noninvasively in vivo with traditional proton (1H) imaging of iron oxide nanoparticle-labeled cells. Alternatively, we demonstrate that fluorine (19F) MRI of cells lab
Autor:
J. Chris Eagon, Todd E. Meyerrose, Mark S. Sands, Louisa Wirthlin, Marc A. Hedrick, Leonard D. Shultz, Daniel A. De Ugarte, A. Alex Hofling, Phillip E. Herrbrich, Jan A. Nolta, Taylor D. Cordonnier
Publikováno v:
Stem Cells. 25:220-227
The potential for human adipose-derived mesenchymal stem cells (AMSC) to traffic into various tissue compartments was examined using three murine xenotransplantation models: nonobese diabetic/severe combined immunodeficient (NOD/SCID), nude/NOD/SCID,
Autor:
Phillip E. Herrbrich, Timothy P. Craft, Todd E. Meyerrose, Michael H. Creer, David A. Hess, Jan A. Nolta, Louisa Wirthlin
Publikováno v:
Blood. 104:1648-1655
Human hematopoietic stem cells (HSCs) are commonly purified by the expression of cell surface markers such as CD34. Because cell phenotype can be altered by cell cycle progression or ex vivo culture, purification on the basis of conserved stem cell f
Publikováno v:
Molecular Therapy. 8:29-41
Clinical trials evaluating the herpes simplex virus thymidine kinase (HSV-tk)/ganciclovir (GCV) suicide gene therapy system for the control of graft-versus-host disease (GVHD) have been limited by low transduction efficiencies and inefficient selecti
Autor:
Craig T. Jordan, Gordon L. Phillips, Dianna S. Howard, David A. Rizzieri, Stephen J. Szilvassy, Todd E. Meyerrose, D Upchurch, Randall M. Rossi, Monica L. Guzman, AL Pettigrew, Selina M. Luger, Barry Grimes
Publikováno v:
Leukemia. 14:1777-1784
Recent studies suggest that the population of malignant cells found in human acute myelogenous leukemia (AML) arises from a rare population of leukemic stem cells (LSCs). LSCs have been documented for nearly all AML subtypes and have been phenotypica
Autor:
Todd E. Meyerrose, Barry Grimes, G Van Zant, de Gerald Haan, Stephen J. Szilvassy, Bert Dontje
Publikováno v:
Blood. 96:1374-1379
We have previously demonstrated that young adult DBA/2 (DBA) mice have more stem cells than C57BL/6 (B6) mice, as measured in a cobblestone area-forming cell (CAFC) assay using unfractionated marrow. To study the nature of this difference, we have no
Autor:
Gerhard Bauer, Todd E. Meyerrose, Xiuli Wang, Susie Csik, Jon Walker, Jesusa Arevalo, Donald B. Kohn, Mo A. Dao, Phillip E. Herrbrich, Jan A. Nolta, Karen Pepper, Louisa Wirthlin, Scott S. Case, Dianne C. Skelton, Ping Zhou
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 16(7)
Serious adverse events in some human gene therapy clinical trials have raised safety concerns when retroviral or lentiviral vectors are used for gene transfer. We evaluated the potential for generating replication-competent retro-virus (RCR) and asse