Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Todd E Morgan"'
Autor:
Michelle Connor, Krista Lamorie-Foote, Qinghai Liu, Kristina Shkirkova, Hans Baertsch, Constantinos Sioutas, Todd E Morgan, Caleb E Finch, William J Mack
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253766 (2021)
Exposure to ambient air pollution has been associated with white matter damage and neurocognitive decline. However, the mechanisms of this injury are not well understood and remain largely uncharacterized in experimental models. Prior studies have sh
Externí odkaz:
https://doaj.org/article/dd6184e738a546fcb0c1be14f9bc13fe
Autor:
Amin Haghani, Mafalda Cacciottolo, Kevin R Doty, Carla D'Agostino, Max Thorwald, Nikoo Safi, Morgan E Levine, Constantinos Sioutas, Terrence C Town, Henry Jay Forman, Hongqiao Zhang, Todd E Morgan, Caleb E Finch
Publikováno v:
eLife, Vol 9 (2020)
The neurotoxicity of air pollution is undefined for sex and APOE alleles. These major risk factors of Alzheimer’s disease (AD) were examined in mice given chronic exposure to nPM, a nano-sized subfraction of urban air pollution. In the cerebral cor
Externí odkaz:
https://doaj.org/article/5fa0c904d51e484a90e16f594b2bc0ac
Autor:
Robin Babadjouni, Arati Patel, Qinghai Liu, Kristina Shkirkova, Krista Lamorie-Foote, Michelle Connor, Drew M Hodis, Hank Cheng, Constantinos Sioutas, Todd E Morgan, Caleb E Finch, William J Mack
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206934 (2018)
Epidemiological studies have established an association between air pollution particulate matter exposure (PM2.5) and neurocognitive decline. Experimental data suggest that microglia play an essential role in air pollution PM-induced neuroinflammatio
Externí odkaz:
https://doaj.org/article/1d52bae5e218486799926417ada22e48
Autor:
Qinghai Liu, Robin Babadjouni, Ryan Radwanski, Hank Cheng, Arati Patel, Drew M Hodis, Shuhan He, Peter Baumbacher, Jonathan J Russin, Todd E Morgan, Constantinos Sioutas, Caleb E Finch, William J Mack
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153376 (2016)
This study examines the effects of nano-size particulate matter (nPM) exposure in the setting of murine reperfused stroke. Particulate matter is a potent source of inflammation and oxidative stress. These processes are known to influence stroke progr
Externí odkaz:
https://doaj.org/article/b1cf5b36668f47278092cde797c09139
Autor:
Sebastian Brandhorst, Morgan E. Levine, Min Wei, Mahshid Shelehchi, Todd E. Morgan, Krishna S. Nayak, Tanya Dorff, Kurt Hong, Eileen M. Crimmins, Pinchas Cohen, Valter D. Longo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing damaged cells including cancer and autoimmune cells, reduce inflammation, promote multi-system regeneration, and extend longevity. Here, we perform
Externí odkaz:
https://doaj.org/article/07535cae9755447cbf16d32138fdada8
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2013)
Pgrmc1 expression in microglia was recently shown by the present authors to mediate estrogen-progesterone interactions during axonal sprouting and to mediate microglial activation itself. We discuss these findings in relation to other functions of Pg
Externí odkaz:
https://doaj.org/article/63b5a425f2b24db39dcbfe62e6d522f8
Autor:
David A Davis, Marco Bortolato, Sean C Godar, Thomas K Sander, Nahoko Iwata, Payam Pakbin, Jean C Shih, Kiros Berhane, Rob McConnell, Constantinos Sioutas, Caleb E Finch, Todd E Morgan
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64128 (2013)
Emerging evidence suggests that excessive exposure to traffic-derived air pollution during pregnancy may increase the vulnerability to neurodevelopmental alterations that underlie a broad array of neuropsychiatric disorders. We present a mouse model
Externí odkaz:
https://doaj.org/article/24a58c963b1b498eb1dd3176e09a7de1
Autor:
Liqin Zhao, Todd E Morgan, Zisu Mao, Sharon Lin, Enrique Cadenas, Caleb E Finch, Christian J Pike, Wendy J Mack, Roberta D Brinton
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31267 (2012)
This study investigated the impact of chronic exposure to continuous (CoP4) versus cyclic progesterone (CyP4) alone or in combination with 17β-estradiol (E2) on gene expression profiles targeting bioenergetics, metabolism and inflammation in the adu
Externí odkaz:
https://doaj.org/article/29a90961d2dc4f9dbafced21b57c30d7
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e8898 (2010)
Although microRNAs are being extensively studied for their involvement in cancer and development, little is known about their roles in Alzheimer's disease (AD). In this study, we used microarrays for the first joint profiling and analysis of miRNAs a
Externí odkaz:
https://doaj.org/article/2aaebe921ae54d98b3ef85088001c7d7
Alzheimer’s Disease associations of ferritin and glutathione with oxidative damage and neuronal loss
Autor:
Max A. Thorwald, Jose A. Godoy-Lugo, Justine Silva, Elizabeth Head, Peggy A. O’Day, Todd E. Morgan, Henry Jay Forman, Caleb E. Finch
Publikováno v:
bioRxiv
The role of reactive iron in Alzheimer’s Disease (AD) has major gaps. Little is known of AD changes in iron transport, glutathione-mediated oxidative repair, and associations with ApoE alleles. Intravascular blood was minimized by washing minced po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2526a2d61bcaa4795da67af826f14228
https://europepmc.org/articles/PMC10081222/
https://europepmc.org/articles/PMC10081222/