Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Todd E Fox"'
Autor:
Kelly Drews, Michael P Calgi, William Casey Harrison, Camille M Drews, Pedro Costa-Pinheiro, Jeremy Joseph Porter Shaw, Kendra A Jobe, John D Han, Todd E Fox, Judith M White, Mark Kester
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228735 (2020)
Influenza virus is an enveloped virus wrapped in a lipid bilayer derived from the host cell plasma membrane. Infection by influenza virus is dependent on these host cell lipids, which include sphingolipids. Here we examined the role of the sphingolip
Externí odkaz:
https://doaj.org/article/5b14755e8b19477ea508fe6d64f8e37f
Autor:
Lindsay K Ryland, Ushma A Doshi, Sriram S Shanmugavelandy, Todd E Fox, Cesar Aliaga, Kathleen Broeg, Kendall Thomas Baab, Megan Young, Osman Khan, Jeremy K Haakenson, Nancy Ruth Jarbadan, Jason Liao, Hong-Gang Wang, David J Feith, Thomas P Loughran, Xin Liu, Mark Kester
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84648 (2013)
Ceramide is a sphingolipid metabolite that induces cancer cell death. When C6-ceramide is encapsulated in a nanoliposome bilayer formulation, cell death is selectively induced in tumor models. However, the mechanism underlying this selectivity is unk
Externí odkaz:
https://doaj.org/article/52a8d45810a54de489ffc56023744a35
Autor:
Tzu-Yu Feng, Stephanie J. Melchor, Xiao-Yu Zhao, Haider Ghumman, Mark Kester, Todd E. Fox, Sarah E. Ewald
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17411- (2023)
Cachexia is a life-threatening disease characterized by chronic, inflammatory muscle wasting and systemic metabolic impairment. Despite its high prevalence, there are no efficacious therapies for cachexia. Mice chronically infected with the protozoan
Externí odkaz:
https://doaj.org/article/b1649d28e32c4015a861690276b43c47
Autor:
Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, Kazuyuki Kitatani
Publikováno v:
Cells, Vol 13, Iss 5, p 405 (2024)
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic agents, induce necroptosis by targeting the activating protein mixed lineage
Externí odkaz:
https://doaj.org/article/25245639c9bc45fd9cd5ba12f6ade3db
Autor:
Harumi Sakae, Yuri Ogiso, Masaya Matsuda, Hayato Shimora, Tye Deering, Todd E. Fox, Mark Kester, Takeshi Nabe, Kazuyuki Kitatani
Publikováno v:
Cells, Vol 12, Iss 4, p 591 (2023)
Ceramides are an emerging class of anti-inflammatory lipids, and nanoscale ceramide-delivery systems are potential therapeutic strategies for inflammatory diseases. This study investigated the therapeutic effects of ceramide nanoliposomes (CNL) on ty
Externí odkaz:
https://doaj.org/article/e4bacdbd851a4eee936b00b945f1d238
Autor:
Brian M. Barth, Weiyuan Wang, Paul T. Toran, Todd E. Fox, Charyguly Annageldiyev, Regina M. Ondrasik, Nicole R. Keasey, Timothy J. Brown, Viola G. Devine, Emily C. Sullivan, Andrea L. Cote, Vasiliki Papakotsi, Su-Fern Tan, Sriram S. Shanmugavelandy, Tye G. Deering, David B. Needle, Stephan T. Stern, Junjia Zhu, Jason Liao, Aaron D. Viny, David J. Feith, Ross L. Levine, Hong-Gang Wang, Thomas P. Loughran, Jr, Arati Sharma, Mark Kester, David F. Claxton
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2598-2603 (2019)
Externí odkaz:
https://doaj.org/article/c4625d35b02b4dee8bf8588d9b18b16d
Autor:
B. Bishal Paudel, Su-Fern Tan, Todd E. Fox, Johnson Ung, Jeremy Shaw, Wendy Dunton, Irene Lee, Arati Sharma, Aaron D. Viny, Brian M. Barth, Martin S. Tallman, Myles Cabot, Francine E. Garrett-Bakelman, Ross L. Levine, Mark Kester, David Claxton, David J. Feith, Kevin A. Janes, Thomas P. Loughran
Publikováno v:
bioRxiv
Acute myeloid leukemia (AML) is an aggressive disease with complex and heterogeneous biology. Although several genomic classifications have been proposed, there is a growing interest in going beyond genomics to stratify AML. In this study, we profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d818fb462fe8955009591cb49d720dd6
https://europepmc.org/articles/PMC10153188/
https://europepmc.org/articles/PMC10153188/
Autor:
Mark Kester, Todd E. Fox, Mark J. Jameson, Pedro Costa-Pinheiro, Michael H. Raymond, Alexandra Hickman, Tara Caste, Tristen Slamowitz, Patrick J. Beck, Emily Venner, Timothy L. Boyer, Jeremy J.P. Shaw
Inducing or Inhibiting Early Stage Autophagy Does Not Alter CNL-Induced Cell Death in HNSCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886e3d6cfc93703ee25564c42fe84503
https://doi.org/10.1158/1535-7163.22518915
https://doi.org/10.1158/1535-7163.22518915
Autor:
Mark Kester, Todd E. Fox, Mark J. Jameson, Pedro Costa-Pinheiro, Michael H. Raymond, Alexandra Hickman, Tara Caste, Tristen Slamowitz, Patrick J. Beck, Emily Venner, Timothy L. Boyer, Jeremy J.P. Shaw
Therapies for head and neck squamous cell carcinoma (HNSCC) are, at best, moderately effective, underscoring the need for new therapeutic strategies. Ceramide treatment leads to cell death as a consequence of mitochondrial damage by generating oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e9505519539f89dd00230139069196
https://doi.org/10.1158/1535-7163.c.6542178
https://doi.org/10.1158/1535-7163.c.6542178
Autor:
Mark Kester, Todd E. Fox, Mark J. Jameson, Pedro Costa-Pinheiro, Michael H. Raymond, Alexandra Hickman, Tara Caste, Tristen Slamowitz, Patrick J. Beck, Emily Venner, Timothy L. Boyer, Jeremy J.P. Shaw
Inhibitors and Inducers of Autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f892e467e660f8b88fcf8f61ded1f8e
https://doi.org/10.1158/1535-7163.22518906
https://doi.org/10.1158/1535-7163.22518906