Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Todd E, Scheetz"'
Autor:
Shruti V. Patil, Balasankara Reddy Kaipa, Sujata Ranshing, Yogapriya Sundaresan, J. Cameron Millar, Bhavani Nagarajan, Charles Kiehlbauch, Qihong Zhang, Ankur Jain, Charles C. Searby, Todd E. Scheetz, Abbot F. Clark, Val C. Sheffield, Gulab S. Zode
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Mutations in myocilin (MYOC) are the leading known genetic cause of primary open-angle glaucoma, responsible for about 4% of all cases. Mutations in MYOC cause a gain-of-function phenotype in which mutant myocilin accumulates in the endoplas
Externí odkaz:
https://doaj.org/article/30e1fedfb0d445a39df2b98bbdbfd4a5
Autor:
Adam P. DeLuca, PhD, S. Scott Whitmore, PhD, Nicole J. Tatro, BSE, Jeaneen L. Andorf, BA, Ben P. Faga, BS, Laurel A. Faga, BS, Malia M. Colins, BA, Meagan A. Luse, BS, Beau J. Fenner, MD, PhD, Edwin M. Stone, MD, PhD, Todd E. Scheetz, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100397- (2023)
Purpose: Choroideremia is an X-linked choroidopathy caused by pathogenic variants in the CHM gene. It is characterized by the early appearance of multiple scotomas in the peripheral visual field that spread and coalesce, usually sparing central visio
Externí odkaz:
https://doaj.org/article/d0d6f23a7ef9472fabe9f324945bdab8
Autor:
Carly van der Heide, Wes Goar, Kacie J. Meyer, Wallace L. M. Alward, Erin A. Boese, Nathan C. Sears, Ben R. Roos, Young H. Kwon, Adam P. DeLuca, Owen M. Siggs, Claudia Gonzaga-Jauregui, Val C. Sheffield, Kai Wang, Edwin M. Stone, Robert F. Mullins, Michael G. Anderson, Bao Jian Fan, Robert Ritch, Jamie E. Craig, Janey L. Wiggs, Todd E. Scheetz, John H. Fingert
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Glaucoma is a leading cause of visual disability and blindness. Release of iris pigment within the eye, pigment dispersion syndrome (PDS), can lead to one type of glaucoma known as pigmentary glaucoma. PDS has a genetic component,
Externí odkaz:
https://doaj.org/article/ce7f241b20c8405bb3d1d6a9635ffb16
Autor:
Nickolas A. Boehme, Adam Hedberg-Buenz, Nicole Tatro, Michael Bielecki, William C. Castonguay, Todd E. Scheetz, Michael G. Anderson, Laura M. Dutca
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Traumatic brain injuries (TBI) of varied types are common across all populations and can cause visual problems. For military personnel in combat settings, injuries from blast exposures (bTBI) are prevalent and arise from a myriad of differen
Externí odkaz:
https://doaj.org/article/ccfdf23006a846fa89fdb7f62743a8b4
Autor:
Elliott H. Sohn, MD, Ian C. Han, MD, Benjamin R. Roos, BS, Benjamin Faga, BS, Meagan A. Luse, BS, Elaine M. Binkley, MD, H. Culver Boldt, MD, James C. Folk, MD, Stephen R. Russell, MD, Robert F. Mullins, PhD, John H. Fingert, MD, PhD, Edwin M. Stone, MD, PhD, Todd E. Scheetz, PhD
Publikováno v:
Ophthalmology Science, Vol 1, Iss 1, Pp 100002- (2021)
Purpose: To evaluate the first association specific to exudative age-related macular degeneration (AMD) located near the matrix metalloproteinase 9 (MMP9) gene. Design: Genetic association study. Participants: One thousand seven hundred twelve patien
Externí odkaz:
https://doaj.org/article/e464e9fd67834a58a547928b16aa7e00
Autor:
Aminatta Z. Tejan-Kamara, Erin A. Boese, Andrew Pouw, Nathan C. Sears, Ben R. Roos, Edwin M. Stone, Todd, E. Scheetz, John H. Fingert
Publikováno v:
Ophthalmology Glaucoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9da9e5024ff6d70a6bd8ad1befd7730
https://doi.org/10.1016/j.ogla.2023.05.006
https://doi.org/10.1016/j.ogla.2023.05.006
Autor:
Andrew P Voigt, Nathaniel K Mullin, Kelly Mulfaul, Lola P Lozano, Luke A Wiley, Miles J Flamme-Wiese, Erin A Boese, Ian C Han, Todd E Scheetz, Edwin M Stone, Budd A Tucker, Robert F Mullins
Publikováno v:
Human Molecular Genetics. 31:2406-2423
The human choroid is a heterogeneous, highly vascular connective tissue that dysfunctions in age-related macular degeneration (AMD). In this study, we performed single-cell RNA sequencing on 21 human choroids, 11 of which were derived from donors wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cff17cffeccd72dfeee48431afefd9
https://doi.org/10.1093/hmg/ddac043
https://doi.org/10.1093/hmg/ddac043
Autor:
Neal G. Copeland, Nancy A. Jenkins, Todd E. Scheetz, David A. Largaespada, Pentao Liu, Timothy K. Starr, Kishore Nannapaneni, Jinsil Kim, Laura M. Rogers, Adam J. Dupuy
Supplementary Tables 1-3 from A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a819fed6d4238310936a67f365e3e0
https://doi.org/10.1158/0008-5472.22378568.v1
https://doi.org/10.1158/0008-5472.22378568.v1
Autor:
Neal G. Copeland, Nancy A. Jenkins, Todd E. Scheetz, David A. Largaespada, Pentao Liu, Timothy K. Starr, Kishore Nannapaneni, Jinsil Kim, Laura M. Rogers, Adam J. Dupuy
Supplementary Table 5 from A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554a402e731a5959d2d9c917e49a443f
https://doi.org/10.1158/0008-5472.22378574
https://doi.org/10.1158/0008-5472.22378574
Autor:
Neal G. Copeland, Nancy A. Jenkins, Todd E. Scheetz, David A. Largaespada, Pentao Liu, Timothy K. Starr, Kishore Nannapaneni, Jinsil Kim, Laura M. Rogers, Adam J. Dupuy
Supplementary Table 4 from A Modified Sleeping Beauty Transposon System That Can Be Used to Model a Wide Variety of Human Cancers in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0441cd595eeb8d1c013c2e7bb14dff35
https://doi.org/10.1158/0008-5472.22378577.v1
https://doi.org/10.1158/0008-5472.22378577.v1