Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Todd E, Barnhart"'
Autor:
Aeli P. Olson, Francesca A. Verich, Paul A. Ellison, Eduardo Aluicio-Sarduy, Robert J. Nickles, Jason C. Mixdorf, Todd E. Barnhart, Jonathan W. Engle
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Background Radiopharmaceutical therapy (RPT) uses radionuclides that decay via one of three therapeutically relevant decay modes (alpha, beta, and internal conversion (IC) / Auger electron (AE) emission) to deliver short range, highly damagi
Externí odkaz:
https://doaj.org/article/bd7a1f32d5d646aeba1c1adab2b7ba71
Autor:
Hao Wei, Dawei Jiang, Bo Yu, Dalong Ni, Mengting Li, Yin Long, Paul A. Ellison, Cerise M. Siamof, Liang Cheng, Todd E. Barnhart, Hyung-Jun Im, Faquan Yu, Xiaoli Lan, Xiaohua Zhu, Qianjun He, Weibo Cai
Publikováno v:
Bioactive Materials, Vol 19, Iss , Pp 282-291 (2023)
Acute kidney injury (AKI) leads to unacceptably high mortality due to difficulties in timely intervention and less efficient renal delivery of therapeutic drugs. Here, a series of polyvinylpyrrolidone (PVP)-curcumin nanoparticles (PCurNP) are designe
Externí odkaz:
https://doaj.org/article/b926ed7951d44e17b8137e34c266f6d8
Autor:
Kaelyn V. Becker, Eduardo Aluicio-Sarduy, Tyler Bradshaw, Samuel A. Hurley, Aeli P. Olson, Kendall E. Barrett, Jeanine Batterton, Paul A. Ellison, Todd E. Barnhart, Ali Pirasteh, Jonathan W. Engle
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Introduction:43Sc and 44gSc are both positron-emitting radioisotopes of scandium with suitable half-lives and favorable positron energies for clinical positron emission tomography (PET) imaging. Irradiation of isotopically enriched calcium targets ha
Externí odkaz:
https://doaj.org/article/3f5b9682387844a0b987e64508d88774
Autor:
Dalong Ni, Dawei Jiang, Christopher J. Kutyreff, Jianhao Lai, Yongjun Yan, Todd E. Barnhart, Bo Yu, Hyung-Jun Im, Lei Kang, Steve Y. Cho, Zhaofei Liu, Peng Huang, Jonathan W. Engle, Weibo Cai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
There are currently no effective therapies available for acute kidney injury (AKI). Here the authors generate molybdenum-based polyoxometalate nanoclusters and show that these have preferential renal uptake and can ameliorate AKI pathology in mice by
Externí odkaz:
https://doaj.org/article/5959a910616a4c1bb0a94672ebd75639
Autor:
Lei Kang, Cuicui Li, Zachary T. Rosenkrans, Nan Huo, Zhao Chen, Emily B. Ehlerding, Yan Huo, Carolina A. Ferreira, Todd E. Barnhart, Jonathan W. Engle, Rongfu Wang, Dawei Jiang, Xiaojie Xu, Weibo Cai
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Lymphoma is a heterogeneous disease with varying clinical manifestations and outcomes. Many subtypes of lymphoma, such as Burkitt′s lymphoma and diffuse large B cell lymphoma, are highly aggressive with dismal prognosis even after conventi
Externí odkaz:
https://doaj.org/article/ba8eeb40dcf54aebb52bd8942f27fe72
Autor:
Zachary T. Rosenkrans, Tuanwei Sun, Dawei Jiang, Weiyu Chen, Todd E. Barnhart, Ziyi Zhang, Carolina A. Ferreira, Xudong Wang, Jonathan W. Engle, Peng Huang, Weibo Cai
Publikováno v:
Advanced Science, Vol 7, Iss 12, Pp n/a-n/a (2020)
Abstract The manifestation of acute kidney injury (AKI) is associated with poor patient outcomes, with treatment options limited to hydration or renal replacement therapies. The onset of AKI is often associated with a surfeit of reactive oxygen speci
Externí odkaz:
https://doaj.org/article/551f1bf2b6b648e9b5b42f207b2a7239
Autor:
Shiyong Li, Ye Wang, Dawei Jiang, Dalong Ni, Christopher J. Kutyreff, Todd E. Barnhart, Jonathan W. Engle, Weibo Cai
Publikováno v:
Advanced Science, Vol 7, Iss 4, Pp n/a-n/a (2020)
Abstract Intrathecal injection, drugs transporting along perivascular spaces, represents an important route for maintaining blood–brain barrier (BBB) integrity after cerebral ischemia/reperfusion (I/R) injury. However, after being directly injected
Externí odkaz:
https://doaj.org/article/473acb290e4843eaae8276f34681f1a0
Autor:
Rebecca L. Koscik, Tobey J. Betthauser, Erin M. Jonaitis, Samantha L. Allison, Lindsay R. Clark, Bruce P. Hermann, Karly A. Cody, Jonathan W. Engle, Todd E. Barnhart, Charles K. Stone, Nathaniel A. Chin, Cynthia M. Carlsson, Sanjay Asthana, Bradley T. Christian, Sterling C. Johnson
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction This study applies a novel algorithm to longitudinal amyloid positron emission tomography (PET) imaging to identify age‐heterogeneous amyloid trajectory groups, estimate the age and duration (chronicity) of amyloid positivity,
Externí odkaz:
https://doaj.org/article/e35cbdf8723f4454881e8468a67b6cb1
Autor:
Dongdong Wang, Ruohong Shi, Jiajia Zhou, Sixiang Shi, Huihui Wu, Pengping Xu, Hui Wang, Guoliang Xia, Todd E. Barnhart, Weibo Cai, Zhen Guo, Qianwang Chen
Publikováno v:
iScience, Vol 9, Iss , Pp 14-26 (2018)
Summary: Therapeutic effects of photodynamic therapy (PDT) remain largely limited because of tumor hypoxia. Herein, we report safe and versatile nanocatalysts (NCs) for endogenous oxygen generation and imaging-guided enhanced PDT. The NCs (named as P
Externí odkaz:
https://doaj.org/article/e7c4afaf562d4b77bc04913e67e2c0d4
Autor:
Isidro Da Silva, Taylor R. Johnson, Jason C. Mixdorf, Eduardo Aluicio-Sarduy, Todd E. Barnhart, R. Jerome Nickles, Jonathan W. Engle, Paul A. Ellison
Publikováno v:
Molecules, Vol 26, Iss 24, p 7513 (2021)
Background: Radionuclides emitting Auger electrons (AEs) with low (0.02–50 keV) energy, short (0.0007–40 µm) range, and high (1–10 keV/µm) linear energy transfer may have an important role in the targeted radionuclide therapy of metastatic an
Externí odkaz:
https://doaj.org/article/8f393569209842f2ada7b320b537314d