Výsledky vyhledávání - "Todd C. Burwell"

Akademický článek

Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

Autor: Marie K. Kirby, Ryne C. Ramaker, Brian S. Roberts, Brittany N. Lasseigne, David S. Gunther, Todd C. Burwell, Nicholas S. Davis, Zulfiqar G. Gulzar, Devin M. Absher, Sara J. Cooper, James D. Brooks, Richard M. Myers

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)

Abstract Background Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic modification that is detectable in peripheral patient fluids such as urine and blo

Externí odkaz: https://doaj.org/article/9a39d794a64a48a3a8bfb311493a6d59

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Supplementary Materials and Methods, Supplementary Figures 1 through 4, and Supplementary Tables 1 and 2 from Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes

Autor: Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Donald J. Buchsbaum, Christos Vaklavas, Todd C. Burwell, Erinn Downs-Kelly, Natalie D. Merz, Katherine L. Updike, William E. Grizzle, Dongquan Chen, Yufeng Li, Andres Forero

This file contains: Supplementary Methods for Tissue Processing, RNA-seq, RNA-seq analysis, and Immunohistochemistry. Supplementary Figure 1: Overlap between clusters identified in our data and TNBC subtypes described in previous studies. Supplementa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc0ebc556aafb5e0bffd7f3a5ecaae1
https://doi.org/10.1158/2326-6066.22537210.v1

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Data from Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes

Triple-negative breast cancer (TNBC) is a subtype with heterogeneous patient outcomes. Approximately 40% of patients experience rapid relapse, while the remaining patients have long-term disease-free survival. To determine if there are molecular diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c3047575fc84af0f45c1779f997f467
https://doi.org/10.1158/2326-6066.c.6548350.v1

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Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

Autor: Jason Gertz, Richard M. Myers, Emma C. Dean, Sara J. Cooper, Daniel Savic, Sarah Meadows, Michael J. Garabedian, Ryne C. Ramaker, Todd C. Burwell, Brian S. Roberts

Publikováno v: Genome Medicine

Background The liver X receptors (LXRs, NR1H2 and NR1H3) and peroxisome proliferator-activated receptor gamma (PPARG, NR1C3) nuclear receptor transcription factors (TFs) are master regulators of energy homeostasis. Intriguingly, recent studies sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84b99ca0fc2dd318f4014ff6bda1e1c
https://pubmed.ncbi.nlm.nih.gov/27401066

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DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma

Autor: Mohini A Patil, Devin Absher, Richard M. Myers, Brittany N. Lasseigne, James D. Brooks, Todd C. Burwell

Publikováno v: BMC Medicine

Background Renal cell carcinoma (RCC) is the tenth most commonly diagnosed cancer in the United States. While it is usually lethal when metastatic, RCC is successfully treated with surgery when tumors are confined to the kidney and have low tumor vol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182af6266596beb669f2df050384cbe0

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