Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Todd C Sacktor"'
Autor:
Kim D Allen, Matthew J Regier, Changchi Hsieh, Panayiotis Tsokas, Maya Barnard, Shwetha Phatarpekar, Jason Wolk, Todd C Sacktor, André A Fenton, A Iván Hernández
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0203374 (2018)
The transition from short-term to long-term forms of synaptic plasticity requires protein synthesis and new gene expression. Most efforts to understand experience-induced changes in neuronal gene expression have focused on the transcription products
Externí odkaz:
https://doaj.org/article/3107d3cc03814cc89e1c93bd4807af16
Autor:
Peter Serrano, Eugenia L Friedman, Jana Kenney, Stephen M Taubenfeld, Joshua M Zimmerman, John Hanna, Cristina Alberini, Ann E Kelley, Stephen Maren, Jerry W Rudy, Jerry C P Yin, Todd C Sacktor, André A Fenton
Publikováno v:
PLoS Biology, Vol 6, Iss 12, Pp 2698-2706 (2008)
How long-term memories are stored is a fundamental question in neuroscience. The first molecular mechanism for long-term memory storage in the brain was recently identified as the persistent action of protein kinase Mzeta (PKMzeta), an autonomously a
Externí odkaz:
https://doaj.org/article/1bfbe7a0f11e48f285b78ebd5198a9c3
Autor:
Edith Lesburguères, Laura Melissa Rodríguez Valencia, Todd C. Sacktor, Ain Chung, Christine A. Denny, Alejandro Grau-Perales, Peter J. Bergold, Claudia Jou, Joelle Chorny, Benjamin Rush Hartley, Juan Marcos Alarcon, Kunal Khanna, A. Iván Hernández, Panayiotis Tsokas, Changchi Hsieh, Joseph Bukai, André A. Fenton, Rafael E. Flores-Obando, Nesha S. Burghardt, James E. Cottrell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e6304dbc9ee23824546ed3cf3d7a3b
https://doi.org/10.1111/ejn.15137/v2/response1
https://doi.org/10.1111/ejn.15137/v2/response1
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21568 (2011)
Late-phase long term potentiation (L-LTP) is thought to be the cellular basis for long-term memory (LTM). While LTM as well as L-LTP is known to depend on transcription and translation, it is unclear why brain-derived neurotrophic factor (BDNF) could
Externí odkaz:
https://doaj.org/article/9e1002a66fae4722b5141931afb77bb3
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10400 (2010)
A leading candidate in the process of memory formation is hippocampal long-term potentiation (LTP), a persistent enhancement in synaptic strength evoked by the repetitive activation of excitatory synapses, either by experimental high-frequency stimul
Externí odkaz:
https://doaj.org/article/5e145f6be8804fa28aa636c6f891e27c
Autor:
Stephen Cheley, Todd C. Sacktor, Hagan Bayley, Sven Beushausen, James H. Schwartz, Peter J. Bergold
Binding of cAMP by the five neuronal isoforms (N1-5) of the regulatory (R) subunit of the Aplysia cAMP-dependent protein kinase is diminished in sensory neurons stimulated to produce long-term presynaptic facilitation. To determine how the cAMP-bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91804bd8d542935d202a4c3f06d505a0
https://ora.ox.ac.uk/objects/uuid:ee3db523-5795-4aae-8c11-4b9ac73a2509
https://ora.ox.ac.uk/objects/uuid:ee3db523-5795-4aae-8c11-4b9ac73a2509
Publikováno v:
The Journal of physiology. 590(16)
Anaesthetic preconditioning occurs when a volatile anaesthetic, such as sevoflurane, is administered before a hypoxic or ischaemic insult; this has been shown to improve neuronal recovery after the insult. We found that sevoflurane-induced preconditi
Publikováno v:
Learning & Memory. 1:189-202
We investigated activation of the two major neuronal protein kinase C (PKC) isoforms in Aplysia, Ca(2+)-activated Apl I and Ca(2+)-independent Apl II, during the induction and maintenance of behavioral sensitization of Aplysia defensive reflexes. Act
Autor:
James H. Schwartz, Wayne S. Sossin, Sven Beushausen, Peter J. Bergold, Todd C. Sacktor, KE Kruger
Publikováno v:
The Journal of Neuroscience. 11:2303-2313
We isolated cDNA clones from an Aplysia sensory-cell library encoding two isoforms of protein kinase C (PKC). Several isozyme-specific regions are conserved in the Aplysia kinases, notably the variable regions V5 in the Ca(2+)-dependent PKC (Apl I) a
Publikováno v:
Molecular Brain Research. 9:347-351
We describe some properties on an Mr 30,000 thermolabile and trypsin-sensitive protein that activates phospholipase A2 (PLA2) and which was isolated from nervous tissue of the marine mollusk, Aplysia californica. A similar protein is present in rat c