Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study

Autor: Denis J. Ohlstrom, Christina Sul, Christine U. Vohwinkel, Laura Hernandez-Lagunas, Anis Karimpour-Fard, Peter M. Mourani, Todd C. Carpenter, Eva S. Nozik, Carmen C. Sucharov

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract Acute respiratory distress syndrome is a heterogeneous pathophysiological process responsible for significant morbidity and mortality in pediatric intensive care patients. Diagnosis is defined by clinical characteristics that identify the sy

Externí odkaz: https://doaj.org/article/7e844cd5149341faa365c987cc50aac1

Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics

Autor: Alexandra Tsitsiklis, PhD, Christina M Osborne, MD, Jack Kamm, PhD, Kayla Williamson, MS, Katrina Kalantar, PhD, Gytis Dudas, PhD, Saharai Caldera, BA, Amy Lyden, BA, Michelle Tan, BS, Norma Neff, PhD, Victoria Soesanto, BS, J Kirk Harris, PhD, Lilliam Ambroggio, PhD, Aline B Maddux, MD, Todd C Carpenter, MD, Ron W Reeder, PhD, Chris Locandro, MS, Eric A F Simões, ProfMD, Matthew K Leroue, MD, Mark W Hall, ProfMD, Athena F Zuppa, ProfMD, Joseph Carcillo, ProfMD, Kathleen L Meert, ProfMD, Anil Sapru, ProfMD, Murray M Pollack, ProfMD, Patrick S McQuillen, ProfMD, Daniel A Notterman, ProfMD, J Michael Dean, ProfMD, Matt S Zinter, MD, Brandie D Wagner, PhD, Joseph L DeRisi, ProfPhD, Peter M Mourani, ProfMD, Charles R Langelier, MDPhD

Publikováno v: The Lancet Microbe, Vol 3, Iss 4, Pp e284-e293 (2022)

Summary: Background: Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics

Externí odkaz: https://doaj.org/article/bf9afb105f554ba7841ff015408ec805

Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness

Autor: Michelle Vo, Kristen Miller, Tellen D. Bennett, Peter M. Mourani, Jaime LaVelle, Todd C. Carpenter, R. Scott Watson, Laura L. Pyle, Aline B. Maddux

Publikováno v: Pediatr Pulmonol

We aimed to identify characteristics associated with postdischarge health resource use in children without medical complexity who survived an episode of prolonged mechanical ventilation for respiratory illness. We hypothesized that longer durations o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae68e402254508abf5711ef606fb14b2
https://doi.org/10.1002/ppul.25934

Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study

Autor: Robert A. Berg, Ryan W. Morgan, Ron W. Reeder, Tageldin Ahmed, Michael J. Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Michael Dean, J. Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L. Fink, Deborah Franzon, Aisha H. Frazier, Stuart H. Friess, Kathryn Graham, Mark Hall, David A. Hehir, Christopher M. Horvat, Leanna L. Huard, Tensing Maa, Arushi Manga, Patrick S. McQuillen, Kathleen L. Meert, Peter M. Mourani, Vinay M. Nadkarni, Maryam Y. Naim, Daniel Notterman, Chella A. Palmer, Murray M. Pollack, Anil Sapru, Carleen Schneiter, Matthew P. Sharron, Neeraj Srivastava, Sarah Tabbutt, Bradley Tilford, Shirley Viteri, David Wessel, Heather A. Wolfe, Andrew R. Yates, Athena F. Zuppa, Robert M. Sutton

Publikováno v: Critical care medicine. 51(1)

Arterial diastolic blood pressure (DBP) greater than 25 mm Hg in infants and greater than 30 mm Hg in children greater than 1 year old during cardiopulmonary resuscitation (CPR) was associated with survival to hospital discharge in one prospective st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a05cb98bd6fd25e3adb95f5f2ed3076
https://pubmed.ncbi.nlm.nih.gov/36519983

The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes

Autor: Ryan W. Morgan, Heather A. Wolfe, Ron W. Reeder, Jessica S. Alvey, Aisha H. Frazier, Stuart H. Friess, Tensing Maa, Patrick S. McQuillen, Kathleen L. Meert, Vinay M. Nadkarni, Matthew P. Sharron, Ashley Siems, Andrew R. Yates, Tageldin Ahmed, Michael J. Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Michael Dean, J. Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L. Fink, Deborah Franzon, Mark Hall, David Hehir, Christopher M. Horvat, Leanna L. Huard, Arushi Manga, Peter M. Mourani, Maryam Y. Naim, Daniel Notterman, Murray M. Pollack, Anil Sapru, Carleen Schneiter, Nerraj Srivastava, Sarah Tabbutt, Bradley Tilford, Shirley Viteri, David Wessel, Athena F. Zuppa, Robert A. Berg, Robert M. Sutton

Publikováno v: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, vol 23, iss 11

ObjectivesThe COVID-19 pandemic resulted in adaptations to pediatric resuscitation systems of care. The objective of this study was to determine the temporal association between the pandemic and pediatric in-hospital cardiac arrest (IHCA) process of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4f74e0653ca86304657f183167a5f7
https://escholarship.org/uc/item/1d57n1gd