Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Todd Bunch"'
Autor:
Kent Thudium, Mark Selby, Julie A. Zorn, Gregory Rak, Xi-Tao Wang, Roderick Todd Bunch, Jason M. Hogan, Pavel Strop, Alan J. Korman
Publikováno v:
Cancer Immunology Research. 10:1175-1189
Novel therapeutic approaches combining immune checkpoint inhibitors are needed to improve clinical outcomes for patients with cancer. Lymphocyte-activation gene 3 (LAG-3) is an immune checkpoint molecule that inhibits T-cell activity and antitumor im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998abd82ce6e0d18fac052d7e8514843
https://doi.org/10.1158/2326-6066.cir-22-0057
https://doi.org/10.1158/2326-6066.cir-22-0057
Autor:
Alan J. Korman, Pavel Strop, Jason M. Hogan, Roderick Todd Bunch, Xi-Tao Wang, Gregory Rak, Julie A. Zorn, Mark Selby, Kent Thudium
Novel therapeutic approaches combining immune-checkpoint inhibitors are needed to improve clinical outcomes for patients with cancer. Lymphocyte-activation gene 3 (LAG-3) is an immune-checkpoint molecule that inhibits T-cell activity and antitumor im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f873646c4378fa6cbb3fc2c62d7017
https://doi.org/10.1158/2326-6066.c.6551000.v1
https://doi.org/10.1158/2326-6066.c.6551000.v1
Autor:
Alan J. Korman, Pavel Strop, Jason M. Hogan, Roderick Todd Bunch, Xi-Tao Wang, Gregory Rak, Julie A. Zorn, Mark Selby, Kent Thudium
Supplementary Data from Preclinical Characterization of Relatlimab, a Human LAG-3–Blocking Antibody, Alone or in Combination with Nivolumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105aa7f014ffe63c49424bcb78d4df9
https://doi.org/10.1158/2326-6066.22545668
https://doi.org/10.1158/2326-6066.22545668
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 25K, Figure S5. Effect of nivolumab on CD8+ T-cell subsets and DCs in PBMCs from nivolumab-treated cynomolgus monkeys.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3afeb590b18bc2205b3661f639ca33c
https://doi.org/10.1158/2326-6066.22537295
https://doi.org/10.1158/2326-6066.22537295
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 376K, Figure S2. Epitope of nivolumab on human PD-1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b853d4530e61228723451974fc3c28ae
https://doi.org/10.1158/2326-6066.22537304.v1
https://doi.org/10.1158/2326-6066.22537304.v1
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 400K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e844640ae1ffeb1fc6f84395d28dbf
https://doi.org/10.1158/2326-6066.22537292
https://doi.org/10.1158/2326-6066.22537292
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 22K, Figure S3. Nivolumab inhibits PD-1 interaction with PD-L1 and PD-L2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171e64e5c6eda8b06e46db9ba0ec0274
https://doi.org/10.1158/2326-6066.22537301.v1
https://doi.org/10.1158/2326-6066.22537301.v1
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 239K, Figure S4. A, Expression of PD-1 in CD4 T cells during mixed lymphocyte reaction (MLR). B, Expression of PD-1 and PD-L1 during stimulation of peripheral blood mononuclear cells (PBMC) by superantigen SEB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c943bf1ae098479376b53e375616e33
https://doi.org/10.1158/2326-6066.22537298
https://doi.org/10.1158/2326-6066.22537298
Autor:
Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang
PDF file - 72K, Figure S1. Binding of nivolumab to human T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024e1c67bc7683d5c8b6c266d2f11e3d
https://doi.org/10.1158/2326-6066.22537307.v1
https://doi.org/10.1158/2326-6066.22537307.v1
Autor:
Aiqing He, Terry Van Vleet, Thomas P. Sanderson, R. Todd Bunch, Damir Simic, Emily Haines, Catherine Euler, W. Mike Peden
Publikováno v:
Toxicology. 311:169-177
The corticotrophin releasing factor (CRF) receptor I antagonist, BMS-764459 (evaluated as a potential treatment of affective disorders), was orally dosed to female Sprague-Dawley rats once daily for 2 weeks (vehicle control or 175mg/kg/day). To inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d045bfb4979af101913f448373e86d06
https://doi.org/10.1016/j.tox.2013.06.006
https://doi.org/10.1016/j.tox.2013.06.006