Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Todd B. Parsley"'
Autor:
Eva van der Veer, Amy K. Patick, Leen-Jan van Doorn, Søren Ottosen, Michael R. Hodges, Lu Yang, Anneke K. Raney, K. Zeh, Todd B. Parsley
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:599-608
Miravirsen is a β- d -oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide targeting the liver-specific microRNA-122 (miR-122). Miravirsen demonstrated antiviral activity against hepatitis C virus (HCV) genotype 1b replicons w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4635e0c7f702800a1a57fc9f18a5378f
https://doi.org/10.1128/aac.04220-14
https://doi.org/10.1128/aac.04220-14
Publikováno v:
Journal of Virology. 81:1813-1820
Cryphonectria parasitica strain EP721 is infected with a strain of hypovirus CHV1, CHV1-EP721, and exhibits typical hypovirulence-associated traits such as reduced pigmentation and reduced asexual sporulation. However, the accumulation of the viral d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35faeb007b70af395a7613956811f340
https://doi.org/10.1128/jvi.01625-06
https://doi.org/10.1128/jvi.01625-06
Publikováno v:
Journal of Virology. 76:12008-12022
The limited coding capacity of picornavirus genomic RNAs necessitates utilization of host cell factors in the completion of an infectious cycle. One host protein that plays a role in both translation initiation and viral RNA synthesis is poly(rC) bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53735eaf69f2203ba88421b0aaf313eb
https://doi.org/10.1128/jvi.76.23.12008-12022.2002
https://doi.org/10.1128/jvi.76.23.12008-12022.2002
Publikováno v:
Journal of Biological Chemistry. 274:12867-12876
To study the role of the RNA polymerase domain (3D) in the proteinase substrate recognition and RNA binding properties of poliovirus polypeptide 3CD, we generated recombinant 3C and 3CD polypeptides and purified them to near homogeneity. By using the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf58cd52baa19eea6693c5ec8db1db2
https://doi.org/10.1074/jbc.274.18.12867
https://doi.org/10.1074/jbc.274.18.12867
Publikováno v:
Virology. 218:1-13
Sequence and structure comparisons with homologous trypsin-like serine proteases have predicted the S1-specificity pocket in picornavirus 3C proteinases. In this study, we examine the putative roles of such residues in poliovirus 3C substrate recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ea7406515ca2daaf7bdafac7dbf0d5
https://doi.org/10.1006/viro.1996.0160
https://doi.org/10.1006/viro.1996.0160
Hypoviruses persistently alter multiple phenotypic traits, stably modify gene expression, and attenuate virulence (hypovirulence) of their pathogenic fungal host, the chestnut blight fungus Cryphonectria parasitica . The pleiotropic nature of these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7a30640cbe5219fa77bf4724ac80e4
https://europepmc.org/articles/PMC118008/
https://europepmc.org/articles/PMC118008/
