Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Todd A. Kellogg"'
Autor:
Lakshmikanth L. Chikkamenahalli, Erik Jessen, Cheryl E. Bernard, W.K. Eddie Ip, Margaret Breen-Lyles, Gianluca Cipriani, Suraj R. Pullapantula, Ying Li, Shefaa AlAsfoor, Laura Wilson, Kenneth L. Koch, Braden Kuo, Robert J. Shulman, Bruno P. Chumpitazi, Travis J. McKenzie, Todd A. Kellogg, James Tonascia, Frank A. Hamilton, Irene Sarosiek, Richard McCallum, Henry P. Parkman, Pankaj J. Pasricha, Thomas L. Abell, Gianrico Farrugia, Surendra Dasari, Madhusudan Grover
Publikováno v:
iScience, Vol 27, Iss 3, Pp 108991- (2024)
Summary: Gastrointestinal immune cells, particularly muscularis macrophages (MM) interact with the enteric nervous system and influence gastrointestinal motility. Here we determine the human gastric muscle immunome and its changes in patients with id
Externí odkaz:
https://doaj.org/article/6c7eae83970a49d480513cd5b3e3ac36
Autor:
Derek W. Ebner, Kelli N. Burger, Brendan Broderick, Douglas W. Mahoney, Todd A. Kellogg, Andres Acosta, John B. Kisiel
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 7, Pp 902-910 (2023)
Background and Aims: Bariatric and metabolic surgery (BMS) may adversely affect noninvasive stool tests for colorectal cancer (CRC) screening through several mechanisms. Multitarget stool DNA (mt-sDNA) is approved for CRC screening; however, performa
Externí odkaz:
https://doaj.org/article/5017845365d64e6dbf5d01d23d1d701d
Autor:
Vy Truong Thuy Nguyen, Negar Taheri, Egan L. Choi, Todd A. Kellogg, David R. Linden, Yujiro Hayashi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 369-383 (2023)
Background & Aims: Impaired gastric motor function in the elderly causes reduced food intake leading to frailty and sarcopenia. We previously found that aging-related impaired gastric compliance was mainly owing to depletion of interstitial cells of
Externí odkaz:
https://doaj.org/article/84516f9c6f3544dbae593a8f10ac2921
Autor:
Yujiro Hayashi, David T. Asuzu, Michael R. Bardsley, Gabriella B. Gajdos, Sergiy M. Kvasha, David R. Linden, Rea A. Nagy, Siva Arumugam Saravanaperumal, Sabriya A. Syed, Yoshitaka Toyomasu, Huihuang Yan, Eduardo N. Chini, Simon J. Gibbons, Todd A. Kellogg, Khashayarsha Khazaie, Makoto Kuro-o, Jair Machado Espindola Netto, Mahendra Pal Singh, James G. Tidball, Michelle Wehling-Henricks, Gianrico Farrugia, Tamas Ordog
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 117-145 (2021)
Background & Aims: Gastric dysfunction in the elderly may cause reduced food intake, frailty, and increased mortality. The pacemaker and neuromodulator cells interstitial cells of Cajal (ICC) decline with age in humans, and their loss contributes to
Externí odkaz:
https://doaj.org/article/8b43f8672b2b4107aadaf0a158051895
Autor:
Alina M. Allen, Vijay H. Shah, Terry M. Therneau, Sudhakar K. Venkatesh, Taofic Mounajjed, Joseph J. Larson, Kristin C. Mara, Todd A. Kellogg, Michael L. Kendrick, Travis J. McKenzie, Suzanne M. Greiner, Jiahui Li, Kevin J. Glaser, Michael L. Wells, Timothy J. Gunneson, Richard L. Ehman, Meng Yin
Publikováno v:
Hepatology Communications, Vol 4, Iss 2, Pp 185-192 (2020)
Disease monitoring in nonalcoholic steatohepatitis (NASH) is limited by absence of noninvasive biomarkers of disease regression or progression. We aimed to examine the role of multiparametric three‐dimensional magnetic resonance elastography (3D‐
Externí odkaz:
https://doaj.org/article/621254dadac242a0bb963a39876859b5
Autor:
LaTonya J. Hickson, Larissa G.P. Langhi Prata, Shane A. Bobart, Tamara K. Evans, Nino Giorgadze, Shahrukh K. Hashmi, Sandra M. Herrmann, Michael D. Jensen, Qingyi Jia, Kyra L. Jordan, Todd A. Kellogg, Sundeep Khosla, Daniel M. Koerber, Anthony B. Lagnado, Donna K. Lawson, Nathan K. LeBrasseur, Lilach O. Lerman, Kathleen M. McDonald, Travis J. McKenzie, João F. Passos, Robert J. Pignolo, Tamar Pirtskhalava, Ishran M. Saadiq, Kalli K. Schaefer, Stephen C. Textor, Stella G. Victorelli, Tammie L. Volkman, Ailing Xue, Mark A. Wentworth, Erin O. Wissler Gerdes, Yi Zhu, Tamara Tchkonia, James L. Kirkland
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 446-456 (2019)
Background: Senescent cells, which can release factors that cause inflammation and dysfunction, the senescence-associated secretory phenotype (SASP), accumulate with ageing and at etiological sites in multiple chronic diseases. Senolytics, including
Externí odkaz:
https://doaj.org/article/0d43e885c44b49ce9dfa80c8a91636b9
Autor:
Sabena M. Conley, LaTonya J. Hickson, Todd A. Kellogg, Travis McKenzie, Julie K. Heimbach, Timucin Taner, Hui Tang, Kyra L. Jordan, Ishran M. Saadiq, John R. Woollard, Busra Isik, Mohsen Afarideh, Tamar Tchkonia, James L. Kirkland, Lilach O. Lerman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundChronic inflammatory conditions like obesity may adversely impact the biological functions underlying the regenerative potential of mesenchymal stromal/stem cells (MSC). Obesity can impair MSC function by inducing cellular senescence, a gro
Externí odkaz:
https://doaj.org/article/8ae03efeb23946dc90e24f4a0ac798dd
Autor:
LaTonya J. Hickson, Larissa G.P. Langhi Prata, Shane A. Bobart, Tamara K. Evans, Nino Giorgadze, Shahrukh K. Hashmi, Sandra M. Herrmann, Michael D. Jensen, Qingyi Jia, Kyra L. Jordan, Todd A. Kellogg, Sundeep Khosla, Daniel M. Koerber, Anthony B. Lagnado, Donna K. Lawson, Nathan K. LeBrasseur, Lilach O. Lerman, Kathleen M. McDonald, Travis J. McKenzie, João F. Passos, Robert J. Pignolo, Tamar Pirtskhalava, Ishran M. Saadiq, Kalli K. Schaefer, Stephen C. Textor, Stella G. Victorelli, Tammie L. Volkman, Ailing Xue, Mark A. Wentworth, Erin O. Wissler Gerdes, David B. Allison, Stephanie L. Dickinson, Keisuke Ejima, Elizabeth J. Atkinson, Marc Lenburg, Yi Zhu, Tamara Tchkonia, James L. Kirkland
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Externí odkaz:
https://doaj.org/article/9ed50bb390cb426aa207a5f49e49f8fb
Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis
Autor:
Madhusudan Grover, Simon J. Gibbons, Asha A. Nair, Cheryl E. Bernard, Adeel S. Zubair, Seth T. Eisenman, Laura A. Wilson, Laura Miriel, Pankaj J. Pasricha, Henry P. Parkman, Irene Sarosiek, Richard W. McCallum, Kenneth L. Koch, Thomas L. Abell, William J. Snape, Braden Kuo, Robert J. Shulman, Travis J. McKenzie, Todd A. Kellogg, Michael L. Kendrick, James Tonascia, Frank A. Hamilton, Gianrico Farrugia, the NIDDK Gastroparesis Clinical Research Consortium (GpCRC)
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-10 (2018)
Abstract Background Cellular changes described in human gastroparesis have revealed a role for immune dysregulation, however, a mechanistic understanding of human gastroparesis and the signaling pathways involved are still unclear. Methods Diabetic g
Externí odkaz:
https://doaj.org/article/20e8bd3f92e147689f45774f66978f5d
Autor:
Yuebo Zhang, Kiran R. Somers, Christiane Becari, Katarzyna Polonis, Michaela A. Pfeifer, Alina M. Allen, Todd A. Kellogg, Naima Covassin, Prachi Singh
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Body fat distribution contributes to obesity-related metabolic and cardiovascular disorders. Visceral fat is more detrimental than subcutaneous fat. However, the mechanisms underlying visceral fat-mediated cardiometabolic dysregulation are not comple
Externí odkaz:
https://doaj.org/article/4d33da5e60bb4a37b1db857332b03b91