Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Todd A. Doran"'
Autor:
Lachlan G. Howell, Blake M. Allan, Don A. Driscoll, Daniel Ierodiaconou, Todd A. Doran, Michael A. Weston
Publikováno v:
Drones, Vol 7, Iss 8, p 497 (2023)
Remotely piloted aircraft systems (RPAS, or ‘drones’ hereafter) have potential for surveying waterbird species and habitats, but there is a risk that the disturbance from drones could compromise count accuracy and bird welfare. We examined the re
Externí odkaz:
https://doaj.org/article/7c23830a29dc41d193d0d2315e3ddcea
Publikováno v:
ACS Chem Biol
Selective death of midbrain dopaminergic neurons is a hallmark pathology of Parkinson’s disease (PD), but the molecular mechanisms that initiate the cascade of events resulting in neurodegeneration in PD remain unclear. Compelling evidence suggests
Publikováno v:
Molecules, Vol 24, Iss 12, p 2242 (2019)
Amyloid-β oligomers (AβOs) self-assemble into polymorphic species with diverse biological activities that are implicated causally to Alzheimer’s disease (AD). Synaptotoxicity of AβO species is dependent on their quaternary structure, however, lo
Externí odkaz:
https://doaj.org/article/e4676f299852496cb04e4bbef41a73d3
Autor:
Peng Ge, Mu Yang, Jacob L. Bouchard, Nicolas Dzamko, Simon J. G. Lewis, Glenda M. Halliday, Todd M. Doran
Publikováno v:
Bioconjugate chemistry. 33(2)
The misfolding and subsequent aggregation of amyloidogenic proteins is a classic pathological hallmark of neurodegenerative diseases. Aggregates of the α-synuclein protein (αS) are implicated in Parkinson's disease (PD) pathogenesis, and naturally
Publikováno v:
Chemical communications (Cambridge, England). 58(6)
Protein glycation is a disease associated, non-enzymatic, posttranslational modification generated by endogenous dicarbonyl metabolites. Currently, there is a lack of chemical tools capable of studying protein adducts caused by this class of reactive
Publikováno v:
Physician Assistant Clinics. 3:23-35
Autor:
Raj S. Pruthi, Angela M Smith, Matthew E. Nielsen, Maxim J. McKibben, E. Will Kirby, Joshua P. Langston, Chris M. Gonzalez, Todd J. Doran, Venetia L. Orcutt, Heather Schultz, Brad Hornberger, Allison B. Deal
Publikováno v:
Urology Practice. 4:418-424
Introduction Projections suggest a significant shortage of urologists coupled with an increasing burden of urological disease due to an aging population. To meet this need, urologists have increasingly partnered with advanced practice providers. Howe
Autor:
Irena Suponitsky-Kroyter, Katharina Ronacher, Patrick J. McEnaney, Gerhard Walzl, Ofelia Utset, Andrew B. MacConnell, Kim Stanley, Brian M. Paegel, Marie L. Malone, Thomas Kodadek, Kimberly R. Mendes, Todd M. Doran, Valerie Cavett, John Maina Ndungu
Publikováno v:
ACS Chemical Biology. 12:234-243
The circulating antibody repertoire encodes a patient's health status and pathogen exposure history, but identifying antibodies with diagnostic potential usually requires knowledge of the antigen(s). We previously circumvented this problem by screeni
Autor:
Todd M, Doran, Paige, Dickson, John Maina, Ndungu, Peng, Ge, Irena, Suponitsky-Kroyter, Hongchan, An, Thomas, Kodadek
Publikováno v:
Methods in enzymology. 622
The development of faster and less expensive methods to discover bioactive small molecules remains a high priority in chemical biology. This article discusses one alternative to traditional high-throughput screening: the synthesis and screening of on
Autor:
Irena Suponitsky-Kroyter, Peng Ge, Paige Dickson, Todd M. Doran, John Maina Ndungu, Thomas Kodadek, Hongchan An
The development of faster and less expensive methods to discover bioactive small molecules remains a high priority in chemical biology. This article discusses one alternative to traditional high-throughput screening: the synthesis and screening of on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::471d0926a507daa7ac27e755829e41a3
https://doi.org/10.1016/bs.mie.2019.02.005
https://doi.org/10.1016/bs.mie.2019.02.005