Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Todd A. Anzelon"'
Autor:
Carolien Bastiaanssen, Pilar Bobadilla Ugarte, Kijun Kim, Giada Finocchio, Yanlei Feng, Todd A. Anzelon, Stephan Köstlbacher, Daniel Tamarit, Thijs J. G. Ettema, Martin Jinek, Ian J. MacRae, Chirlmin Joo, Daan C. Swarts, Fabai Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Argonaute proteins are the central effectors of RNA-guided RNA silencing pathways in eukaryotes, playing crucial roles in gene repression and defense against viruses and transposons. Eukaryotic Argonautes are subdivided into two clades: AGOs
Externí odkaz:
https://doaj.org/article/00119b4a7cf949e3816963ef58da50a7
Autor:
Amena Arif, Shannon Bailey, Natsuko Izumi, Todd A. Anzelon, Deniz M. Ozata, Cecilia Andersson, Ildar Gainetdinov, Ian J. MacRae, Yukihide Tomari, Phillip D. Zamore
Publikováno v:
Nature. 608:618-625
Argonaute proteins use nucleic acid guides to find and bind specific DNA or RNA target sequences. Argonaute proteins have diverse biological functions and many retain their ancestral endoribonuclease activity, cleaving the phosphodiester bond between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703fb3283d992e25866ef0b761130585
https://doi.org/10.1038/s41586-022-05009-0
https://doi.org/10.1038/s41586-022-05009-0
Autor:
Todd A. Anzelon, Yao Xiao, Gabriel C. Lander, Saikat Chowdhury, Siobhan M. Hughes, Ian J. MacRae
Publikováno v:
Nature
PIWI proteins use PIWI-interacting RNAs (piRNAs) to identify and silence transposable elements and thereby maintain genome integrity between metazoan generations1. The targeting of transposable elements by PIWI has been compared to mRNA target recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d006012a04dd149fd6d39b3cb4f3e5a
https://doi.org/10.1038/s41586-021-03856-x
https://doi.org/10.1038/s41586-021-03856-x
Autor:
Amena Arif, Shannon Bailey, Natsuko Izumi, Todd A. Anzelon, Deniz M. Ozata, Cecilia Andersson, Ildar Gainetdinov, Ian J. MacRae, Yukihide Tomari, Phillip D. Zamore
Argonaute proteins use nucleic acid guides to find and bind specific DNA or RNA target sequences. Argonaute proteins can be found in all kingdoms of life, and play diverse biological functions including genome defense, gene regulation, and chromosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::643b62ebeb06e66b5f5e52c3e3fae8d1
https://doi.org/10.1101/2021.05.04.442675
https://doi.org/10.1101/2021.05.04.442675
Autor:
Saikat Chowdhury, Siobhan M. Hughes, Ian J. MacRae, Gabriel C. Lander, Yao Xiao, Todd A. Anzelon
SummaryPiwi proteins use PIWI-interacting RNAs (piRNAs) to identify and silence the transposable elements (TEs) pervasively found in animal genomes. The Piwi targeting mechanism is proposed to be similar to targeting by Argonaute proteins, which empl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ca9180ea53aace715eb9f4873026dd
https://doi.org/10.1101/2020.12.07.413112
https://doi.org/10.1101/2020.12.07.413112