Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Todd, McLaughlin"'
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-19 (2022)
Abstract Background The retina, as part of the central nervous system (CNS) with limited capacity for self-reparation and regeneration in mammals, is under cumulative environmental stress due to high-energy demands and rapid protein turnover. These s
Externí odkaz:
https://doaj.org/article/d6289304eeac42d9acb3035f971ba517
Autor:
Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua J. Wang, Xiuqian Mu, Sarah X. Zhang
Publikováno v:
Cells, Vol 12, Iss 12, p 1558 (2023)
p58IPK is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of
Externí odkaz:
https://doaj.org/article/48ecd1f9bfd44090a3e71d17a4fe9acc
Autor:
Todd McLaughlin, Marek Falkowski, Jae Whan Park, Stephen Keegan, Michael Elliott, Joshua J. Wang, Sarah X. Zhang
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-15 (2018)
Abstract Background Aging is the strongest risk factor for neurodegenerative diseases and extended age results in neuronal degeneration and functional decline in the visual system. Among many contributing factors to age-related deterioration of neuro
Externí odkaz:
https://doaj.org/article/099ba4e4a8c94980abef9117bcd3036a
Autor:
Zhang, Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua J. Wang, Xiuqian Mu, Sarah X.
Publikováno v:
Cells; Volume 12; Issue 12; Pages: 1558
p58IPK is a multifaceted endoplasmic reticulum (ER) chaperone and a regulator of eIF2α kinases involved in a wide range of cellular processes including protein synthesis, ER stress response, and macrophage-mediated inflammation. Systemic deletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::7c2a4061b5aaaabe3f4a7885d4fd1e2e
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
p58IPK is an endoplasmic reticulum (ER)-resident chaperone playing a critical role in facilitating protein folding and protein homeostasis. Previously, we have demonstrated that p58IPK is expressed broadly in retinal neurons including retinal ganglio
Externí odkaz:
https://doaj.org/article/409925ed48304de3a8a45e221494a359
Autor:
Todd McLaughlin, Sarah X Zhang
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 8, Pp 1211-1213 (2015)
Externí odkaz:
https://doaj.org/article/4e873e0c1a934a5997e453abd71b9250
Publikováno v:
Molecular neurodegeneration. 17(1)
Background The retina, as part of the central nervous system (CNS) with limited capacity for self-reparation and regeneration in mammals, is under cumulative environmental stress due to high-energy demands and rapid protein turnover. These stressors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8baad8aaed16ab0c4c50eb198d2498
https://pubmed.ncbi.nlm.nih.gov/35346303
https://pubmed.ncbi.nlm.nih.gov/35346303
Autor:
Yaqin Wang, Sarah X. Zhang, Joshua J. Wang, Yun-Zheng Le, Jing Yang, Todd McLaughlin, Chen Chen
Publikováno v:
Diabetologia. 62:531-543
AIMS/HYPOTHESIS: Müller glia (MG) are major sources of retinal cytokines, and their activation is closely linked to retinal inflammation and vascular leakage in diabetic retinopathy. Previously, we demonstrated that X-box binding protein 1 (XBP1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbbc55f18cf944800320d1fb6cd52bf
https://doi.org/10.1007/s00125-018-4776-y
https://doi.org/10.1007/s00125-018-4776-y
Publikováno v:
Frontiers in aging neuroscience. 10
p58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7861598bb7b2010dc70823080ee1bf5
https://pubmed.ncbi.nlm.nih.gov/30245625
https://pubmed.ncbi.nlm.nih.gov/30245625
Publikováno v:
Retinal Degenerative Diseases ISBN: 9783319754017
The molecular chaperone endoplasmic reticulum protein 29 (ERp29) plays a critical role in protein folding, trafficking, and secretion. Though ubiquitously expressed, ERp29 is upregulated in response to ER stress and is found at higher levels in certa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bcb601034fc428ceaae978477ebe7a
https://europepmc.org/articles/PMC6040649/
https://europepmc.org/articles/PMC6040649/
