Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Todd, Gierahn"'
Publikováno v:
The Journal of Immunology. 208:172.09-172.09
Biological resolution at the level of individual cells is powering the next phase of precision health. Honeycomb Biotechnologies currently offers an assay for single-cell RNA sequencing with the HIVE™ scRNAseq Solution. The HIVE is a portable, hand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7dcfbbb2fa4ac049b92b58b092179b2
https://doi.org/10.4049/jimmunol.208.supp.172.09
https://doi.org/10.4049/jimmunol.208.supp.172.09
Autor:
Yuan Li, Todd Gierahn, Claudette M Thompson, Krzysztof Trzciński, Christopher B Ford, Nicholas Croucher, Paulo Gouveia, Jessica B Flechtner, Richard Malley, Marc Lipsitch
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1002989 (2012)
Antigenic variation to evade host immunity has long been assumed to be a driving force of diversifying selection in pathogens. Colonization by Streptococcus pneumoniae, which is central to the organism's transmission and therefore evolution, is limit
Externí odkaz:
https://doaj.org/article/0505896bdbc84e65a4b2113fbcee6393
Autor:
Junjie, Lu, Xiaobo, Zhu, Jessica E, Shui, Linjie, Xiong, Todd, Gierahn, Cheng, Zhang, Michael, Wood, Suzanne, Hally, J Christopher, Love, Hu, Li, Benjamin C, Crawford, Hongmei, Mou, Paul H, Lerou
Publikováno v:
Pediatric research. 89(3)
Bronchopulmonary dysplasia remains one of the most common complications of prematurity, despite significant improvements in perinatal care. Functional modeling of human lung development and disease, like BPD, is limited by our ability to access the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c0de233741c86792047a46d441e44f9
https://pubmed.ncbi.nlm.nih.gov/32365352
https://pubmed.ncbi.nlm.nih.gov/32365352
Autor:
Jessica Flechtner, Paul J. Giannasca, L. Cristina Gavrilescu, Mojca Skoberne, Scott Munzer, Richard Malley, Bharat Dixit, Kristin Moffitt, Angela Howard, Todd Gierahn
Publikováno v:
Infection and Immunity. 82:2079-2086
Infections with Streptococcus pneumoniae cause substantial morbidity and mortality, particularly in children in developing nations. Polysaccharide-conjugate vaccines provide protection against both invasive disease and colonization, but their use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539708055a9acdf767cc612a6d6718a3
https://doi.org/10.1128/iai.01632-13
https://doi.org/10.1128/iai.01632-13
Autor:
Richard Malley, Jessica Flechtner, Paulo Gouveia, Mark R. Alderson, Todd Gierahn, Darren E. Higgins, Kristin Moffitt, Ying-Jie Lu
Publikováno v:
Cell Host & Microbe. 9(2):158-165
SummaryStreptococcus pneumoniae is a leading cause of mortality in young children. While successful conjugate polysaccharide vaccines exist, a less expensive serotype-independent protein-based pneumococcal vaccine offers a major advancement for preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d210707f1ac51294cef731effe0cdc69
Autor:
Alissa Myrick, Carolyn K. Dong, Karine G. Le Roch, Dyann F. Wirth, Jennifer S. Sims, Elizabeth A. Winzeler, Todd Gierahn, Kevin T. Militello, Anusha Gunasekera
Publikováno v:
Molecular and Biochemical Parasitology. 153:19-30
Control of gene expression is poorly understood in the Plasmodium system, where relatively few homologues to known eukaryotic transcription factors have been uncovered. Recent evidence suggests that the parasite may utilize a combinatorial mode of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae5b7fcf93d3859a412e3a19410e3bf
https://doi.org/10.1016/j.molbiopara.2007.01.011
https://doi.org/10.1016/j.molbiopara.2007.01.011
Autor:
Danielle Garvie, Veronica Clemens, Deborah Long, Jessica Price, Shane Larson, Todd Gierahn, Mojca Skoberne, George R. Siber, Jessica Flechtner, Kenya Prince Cohane, Amy Baccari
Publikováno v:
Virology.
Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by episodic recurrent genital lesions and/or viral shedding. We hypothesize that infected (HSV-2(pos)) asymptomatic individuals have acquired T cell responses to sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfccc013e8f4e6ec8742ff74563a118c
https://pubmed.ncbi.nlm.nih.gov/25108380
https://pubmed.ncbi.nlm.nih.gov/25108380
Publikováno v:
Vaccine. 30(29)
A comprehensive proteomic screening technology was previously used to characterize T cell responses to Chlamydia trachomatis infection. In this study, we demonstrated that T cells specific for protein antigens identified through this comprehensive te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb0d0b4fa2de5cfc86a704febb10852
https://pubmed.ncbi.nlm.nih.gov/22682294
https://pubmed.ncbi.nlm.nih.gov/22682294
To date, it has not been possible to study antigen-specific T cell responses during primary infection of the genital tract. The low frequency of pathogen-specific T cells in a naïve mouse makes it difficult to monitor the initial events after antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8491cacd59d3bf7a074d1a16bd284aa7
https://europepmc.org/articles/PMC1567698/
https://europepmc.org/articles/PMC1567698/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(7)
The present studies address the mechanism of aromatic hydroxylation used by the natural and G103L isoforms of the diiron enzyme toluene 4-monooxygenase. These isoforms have comparable catalytic parameters but distinct regiospecificities for toluene h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14c9477c7843e555fef43db78d0d93d
https://pubmed.ncbi.nlm.nih.gov/12640145
https://pubmed.ncbi.nlm.nih.gov/12640145