Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Tod P Holler"'
Autor:
Richard O Oduor, Kayode K Ojo, Gareth P Williams, Francois Bertelli, James Mills, Louis Maes, David C Pryde, Tanya Parkinson, Wesley C Van Voorhis, Tod P Holler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 4, p e1017 (2011)
Trypanosoma brucei, the causative agent of Human African Trypanosomiasis (HAT), expresses two proteins with homology to human glycogen synthase kinase 3β (HsGSK-3) designated TbruGSK-3 short and TbruGSK-3 long. TbruGSK-3 short has previously been va
Externí odkaz:
https://doaj.org/article/93f326b6948e455bba876c91639f9f81
Autor:
Tod P. Holler, Yan Hong, Zhaofeng Li, Caiming Li, Li Cheng, Yuxian You, Zhengbiao Gu, Chen Di, Yuzhu Zhang, Xiaofeng Ban
Publikováno v:
Trends in Food Science & Technology. 107:389-400
Background The increased consumption of rice noodle, a traditional rice-based product with high nutritional values and pleasant tastes, has led to increased research attention. Traditionally, rice noodle has been produced using a long series of steps
Autor:
Bhalerao Kaustubh, Caiming Li, Zhengbiao Gu, Tod P. Holler, Li Cheng, Yan Hong, Li Zhaofeng, Xiaofeng Ban, Abhishek S. Dhoble
Publikováno v:
Critical Reviews in Biotechnology. 40:380-396
The 1,4-α-glucan branching enzymes (GBEs) are ubiquitously distributed in animals, microorganisms and plants. These enzymes modify the structure of both starch and glycogen; changing the frequency and position of branches by forming new α-1,6-gluco
Publikováno v:
International Journal of Biological Macromolecules. 83:111-116
The amino acid residue Asp 577 is located in calcium-binding site III (CaIII) of the cyclodextrin glycosyltransferase (EC 2.4.1.19, CGTase) from Bacillus circulans STB01. In the present study, the effects of replacing Asp577 with glycine, alanine, va
Publikováno v:
International journal of biological macromolecules. 115
The limits that cyclodextrin products impose on their industrial production from starch by cyclodextrin glycosyltransferases (CGTases) are a severe problem. In this paper, mutants at residue Leu600 of the β-CGTase from Bacillus circulans STB01 were
Publikováno v:
Journal of Bacteriology. 196:2861-2868
Arabinose-5-phosphate isomerases (APIs) catalyze the interconversion of d -ribulose-5-phosphate and d -arabinose-5-phosphate, the first step in the biosynthesis of 3-deoxy- d -manno-octulosonic acid (Kdo), an essential component of the lipopolysaccha
Autor:
Timothy C. Meredith, Pan-Fen Wang, Alejandra Yep, Sara N. Smith, Ronald W. Woodard, Joshua A. Mosberg, Harry L. T. Mobley, Tod P. Holler
Publikováno v:
Journal of Bacteriology. 193:2981-2988
Previous studies showed that deletion of genes c3405 to c3410 from PAI- metV , a genomic island from Escherichia coli CFT073, results in a strain that fails to compete with wild-type CFT073 after a transurethral cochallenge in mice and is deficient i
Publikováno v:
Expert Opinion on Drug Discovery. 4:293-314
Chronic hepatitis C virus (HCV) infection is a main cause of cirrhosis of the liver and hepatocellular carcinoma. The standard of care is a combination of pegylated interferon with ribavirin, a regimen that has undesirable side effects and is frequen
Publikováno v:
Expert Opinion on Drug Discovery. 2:1085-1101
Antibacterial drug discovery has undertaken a major experiment in the 12 years since the first bacterial genomes were sequenced. Genome mining has identified hundreds of potential targets that have been distilled to a relatively small number of broad
Autor:
Jeffrey M. Schaub, Tod P. Holler, M.C. Holt, David L. Cech, Pan Fen Wang, Ronald W. Woodard, Victoria A. Assimon
Publikováno v:
The protein journal. 33(5)
d-Arabinose 5-phosphate isomerases (APIs) catalyze the interconversion of d-ribulose 5-phosphate and d-arabinose 5-phosphate (A5P). A5P is an intermediate in the biosynthesis of 3-deoxy-d-manno-octulosonate (Kdo), an essential component of lipopolysa