Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tod A. Harper"'
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 353:201-212
The aryl hydrocarbon receptor (AhR) is a cytosolic ligand-activated transcription factor historically known for its role in xenobiotic metabolism. Although AhR activity has previously been shown to play a cytoprotective role against intrinsic apoptot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31822fa71ee64bc7136a98c805a0b649
https://doi.org/10.1124/jpet.114.222265
https://doi.org/10.1124/jpet.114.222265
Autor:
William M. Baird, Katrina M. Waters, Lisbeth K. Siddens, Kristi L. Bunde, Susan C. Tilton, Lisa M. Bramer, Sharon K. Krueger, Tammie J. McQuistan, Tod A. Harper, Christiane V. Löhr, David E. Williams
Publikováno v:
Toxicology and applied pharmacology. 287(2)
FVB/N mice wild-type, heterozygous or null for Cyp 1b1 were used in a two-stage skin tumor study comparing PAH, benzo[a]pyrene (BaP), dibenzo[def,p]chrysene (DBC), and coal tar extract (CTE, SRM 1597a). Following 20 weeks of promotion with TPA the Cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6274453683011595d20f2d7c0470927
https://pubmed.ncbi.nlm.nih.gov/26049101
https://pubmed.ncbi.nlm.nih.gov/26049101
Autor:
Jessica M. Hummel, David E. Williams, Scott W. Burchiel, Fredine T. Lauer, Tammie J. McQuistan, Jeff Morré, Tod A. Harper
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 782
The polycyclic aromatic hydrocarbon (PAH), dibenzo[def,p]chrysene (DBC; also known as dibenzo[a,l]pyrene), is a potent carcinogen in animal models and a class 2A human carcinogen. Recent investigations into DBC-mediated toxicity identified DBC as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4083965f94a23759d59cf5aed0d8be77
https://pubmed.ncbi.nlm.nih.gov/25868132
https://pubmed.ncbi.nlm.nih.gov/25868132
Autor:
Michael A. Fuller, Lesley B. Pickford, Ann C. Neale, F. Gerard Moeller, Crystal L. Carbone, Kirsten Z. Reiman, Jason B. Jayroe, Noelle C. Anastasio, Richard De La Garza, Tod A. Harper, Gaylyn J. Holstein, Stephen I. Bandak, Marcy J. Bubar, Thomas F. Newton, David L. Ware, Kathryn A. Cunningham
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 59
In the present study, we tested the hypothesis that the potent and selective dopamine-β-hydroxylase (DβH) inhibitor nepicastat would have minimal effects on cardiovascular and pharmacokinetic parameters associated with cocaine administration and wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730a010ea098f2ec96ff71edad29fa65
https://pubmed.ncbi.nlm.nih.gov/25602710
https://pubmed.ncbi.nlm.nih.gov/25602710
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 344(3)
Proper hepatocyte function is vital for survival; thus, unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver regeneration is clinically impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f87edf81f1d1e7e6556b5423fe6ce73
https://pubmed.ncbi.nlm.nih.gov/23269473
https://pubmed.ncbi.nlm.nih.gov/23269473