Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Toby R. Efferen"'
Autor:
Sandor Szilagyi, Shobhit Negi, Eric D. Peselow, Stephen Gonzenbach, Myrsini Stephanides, John Rotrosen, June Corwin, Marion P. Schwartz, Burt Angrist, Alena Kunzova, Erica Duncan, Toby R. Efferen, Dragana Bugarski-Kirola
Publikováno v:
Schizophrenia Research. 71:239-248
Introduction : The negative and cognitive symptoms of schizophrenia are poorly responsive to neuroleptic treatment. Glutamatergic dysfunction may mediate some of these symptoms. Low dose d -cycloserine (DCS) is a partial agonist at the glycine site o
Autor:
Eric D. Peselow, Stephen Gonzenbach, Dragana Bugarski-Kirola, Shobhit Negi, Sandor Szilagyi, Myrsini Stephanides, Subhajit Chakravorty, Toby R. Efferen, John Rotrosen, Marion P. Schwartz, James Harmon, Alena Kunzova, Erica Duncan
Publikováno v:
Psychiatry Research. 120:1-12
Studies of the acoustic startle response and of its inhibition by the presentation of a non-startling preliminary stimulus (prepulse inhibition, PPI) have revealed deficits in PPI in schizophrenic subjects compared to healthy controls. Animal studies
Autor:
Arti Parwani, Marion P. Schwartz, Sandor Szilagyi, Erica Duncan, John Rotrosen, Burt Angrist, Steven H. Madonick, Toby R. Efferen, Alena Kunzova, James W. Harmon, Stephen Gonzenbach, Subhajit Chakravorty
Publikováno v:
Psychopharmacology. 167:63-71
The acoustic startle response is inhibited when the startling stimulus is preceded by a weaker non-startling acoustic stimulus. This phenomenon, termed prepulse inhibition of acoustic startle (PPI), is impaired in schizophrenics compared to normal co
Autor:
Erica Duncan, Toby R Efferen, Arti Parwani, Burt Angrist, Subhajit Chakravorty, Steven Madonick, John Rotrosen, Stephen Gonzenbach, Sandor Szilagyi
Publikováno v:
Psychopharmacology. 156:266-272
Rationale: Prepulse inhibition of the acoustic startle response (PPI) is a paradigm in which a startle response to an auditory stimulus is reduced when that stimulus is preceded by a lower intensity, non-startling stimulus (prepulse). PPI is used as
Autor:
Elsa Bartlett, Grant N. Ko, Steven H. Madonick, Erica Duncan, Toby R Efferen, Arti Parwani, Phillip B. Chappell, Michael Sanfilipo, John Rotrosen, Stephen Gonzenbach, Rajive Rajan, Subhajit Chakravorty
Publikováno v:
Biological Psychiatry. 47:662-669
Background: Schizophrenics show deficits in sensorimotor gating, as measured by prepulse inhibition of acoustic startle (PPI). The goal of this investigation is to further characterize PPI and habituation deficits in schizophrenia, and to examine whe
Autor:
Pamela D. Butler, Erica Duncan, Toby R Efferen, Stephen Gonzenbach, John Rotrosen, Burt Angrist, Jill U Adams, Sandor Szilagyi, Subhajit Chakravorty
Publikováno v:
Neuropsychopharmacology. 22:89-96
Chronic cocaine use has been shown to produce neurochemical alterations which persist after acute withdrawal. This study assessed the effects of cocaine use on the acoustic startle response and sensorimotor gating using prepulse inhibition (PPI) of s
Publikováno v:
Pharmacology, biochemistry, and behavior. 68(4)
Prepulse inhibition (PPI) of startle is a sensorimotor gating task in which a low-intensity acoustic stimulus presented prior to a high-intensity, startle-eliciting stimulus can attenuate the acoustic startle response (ASR). Previous studies on start