Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Toby Lawrence"'
Autor:
Jérémy Guillot, Chloé Dominici, Adrien Lucchesi, Huyen Thi Trang Nguyen, Angélique Puget, Mélanie Hocine, Martha M. Rangel-Sosa, Milesa Simic, Jérémy Nigri, Fabienne Guillaumond, Martin Bigonnet, Nelson Dusetti, Jimmy Perrot, Jonathan Lopez, Anders Etzerodt, Toby Lawrence, Pierre Pudlo, Florence Hubert, Jean-Yves Scoazec, Serge A. van de Pavert, Richard Tomasini, Sophie Chauvet, Fanny Mann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The autonomic nervous systems densely innervate the pancreas, but its contribution to pancreatic ductal adenocarcinoma (PDAC) progression is not fully understood. Here, the authors characterize the pattern of sympathetic innervation by 3D imaging in
Externí odkaz:
https://doaj.org/article/f2a238503c59462b8745c93b2bc9627d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pulmonary fibrosis is an irreversible and progressive disease affecting the lungs, and the etiology remains poorly understood. This disease can be lethal and currently has no specific clinical therapeutic regimen. Macrophages, the most common type of
Externí odkaz:
https://doaj.org/article/cec1f3b78d3b4c5e9c541c3b9f0a8035
Autor:
Pauline Soulas-Sprauel, Bernhard Ryffel, Corentin Richard, Romain Boidot, Elise Jacquin, Raphael Carapito, Richard A Flavell, Frederique Vegran, Tiffany Martin, Isis Benoit-Lizon, Thaiz Rivera Vargas, Aurélie Roussey, Ludivine Dal Zuffo, Andréa Melis, Daria Vinokurova, Sayyed Hamed Shahoei, Alvaro Baeza Garcia, Cassandre Pignol, Stéphane Giorgiutti, Eric R Nelson, Toby Lawrence, Lionel Apetoh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/010efbccc7be494cbe7e79e2e8c14071
Autor:
Rong Huang, Guo Guo, Liaoxun Lu, Rui Fu, Jing Luo, Zhuangzhuang Liu, Yanrong Gu, Wenyi Yang, Qianqian Zheng, Tianzhu Chao, Le He, Ying Wang, Zhiguo Niu, Hui Wang, Toby Lawrence, Marie Malissen, Bernard Malissen, Yinming Liang, Lichen Zhang
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2006-2019 (2019)
During foam cell formation and atherosclerosis development, the scavenger receptor CD36 plays critical roles in lipid uptake and triggering of atherogenicity via the activation of Vav molecules. The Vav family includes three highly conserved members
Externí odkaz:
https://doaj.org/article/a5f810bddc66490a80ae80db46495b16
Autor:
Franca Cassol, Loriane Portal, Sylvie Richelme, Mathieu Dupont, Yannick Boursier, Maria Arechederra, Nathalie Auphan-Anezin, Lionel Chasson, Caroline Laprie, Samantha Fernandez, Laure Balasse, Fabienne Lamballe, Rosanna Dono, Benjamin Guillet, Toby Lawrence, Christian Morel, Flavio Maina
Publikováno v:
iScience, Vol 21, Iss , Pp 68-83 (2019)
Summary: Computed tomography is a powerful medical imaging modality for longitudinal studies in cancer to follow neoplasia progression and evaluate anticancer therapies. Here, we report the generation of a photon-counting micro-computed tomography (P
Externí odkaz:
https://doaj.org/article/4ac8f497746640ab8599f6ebf470943e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Plasmacytoid dendritic cells (pDCs) are a special subtype of dendritic cells with the morphology of plasma cells. pDCs produce massive amounts of type I interferon (IFN-I), which was originally found to play an extremely pivotal role in antiviral imm
Externí odkaz:
https://doaj.org/article/d652d02e7ac944039f38e0e0040d647d
Autor:
Hannah Wilkinson, Hugh Leonard, Daxin Chen, Toby Lawrence, Michael Robson, Pieter. Goossens, John H. McVey, Anthony Dorling
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101981- (2021)
Summary: Delayed-type hypersensitivity (DTH) responses underpin chronic inflammation. Using a model of oxazolone-induced dermatitis and a combination of transgenic mice, adoptive cell transfer, and selective agonists/antagonists against protease acti
Externí odkaz:
https://doaj.org/article/551ffa6738e14c87a007eafe68a0d163
Autor:
Mohamed Habbeddine, Christophe Verthuy, Olivia Rastoin, Lionel Chasson, Magali Bebien, Marc Bajenoff, Sahil Adriouch, Joke M.M. den Haan, Josef M. Penninger, Toby Lawrence
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2515-2527 (2017)
The spleen plays an important role in protective immunity to bloodborne pathogens. Macrophages and dendritic cells (DCs) in the spleen marginal zone capture microbial antigens to trigger adaptive immune responses. Marginal zone macrophages (MZMs) can
Externí odkaz:
https://doaj.org/article/705661bb2792462fb2dbd272b8be592d
Autor:
Chih-Yuan Lee, Ting-Yu Lai, Meng-Kun Tsai, Yung-Chi Chang, Yu-Hsin Ho, I-Shing Yu, Tzu-Wen Yeh, Chih-Chang Chou, You-Sheng Lin, Toby Lawrence, Li-Chung Hsu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Caveolae and their major constituent Caveolin-1 (CAV1) play an important role in signalling pathways involved in inflammation, but regulators of CAV1 protein stability are unknown. Here, the authors show that E3 ubiquitin ligase ZNRF1 induces degrada
Externí odkaz:
https://doaj.org/article/c30b0e30686342fe9db885694ae7780d
Autor:
Tianzhu Chao, Zhuangzhuang Liu, Yu Zhang, Lichen Zhang, Rong Huang, Le He, Yanrong Gu, Zhijun Chen, Qianqian Zheng, Lijin Shi, Wenping Zheng, Xinhui Qi, Eryan Kong, Zhongjian Zhang, Toby Lawrence, Yinming Liang, Liaoxun Lu
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
It is a tempting goal to identify causative genes underlying phenotypic differences among inbred strains of mice, which is a huge reservoir of genetic resources to understand mammalian pathophysiology. In particular, the wild-derived mouse strains ha
Externí odkaz:
https://doaj.org/article/863b16560a1f4786b758d2310697bfa8