Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Toby Ferguson"'
Autor:
Alessio Paris, Pranami Bora, Silvia Parolo, Drew MacCannell, Michael Monine, Nick van derMunnik, Xiao Tong, Satish Eraly, Zdenek Berger, Danielle Graham, Toby Ferguson, Enrico Domenici, Ivan Nestorov, Luca Marchetti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 2, Pp 196-206 (2023)
Abstract Phosphorylated neurofilament heavy subunit (pNfH) has been recently identified as a promising biomarker of disease onset and treatment efficacy in spinal muscular atrophy (SMA). This study introduces a quantitative systems pharmacology model
Externí odkaz:
https://doaj.org/article/9c84e240cf754f71aacd8847664a671a
Autor:
Alessio Paris, Pranami Bora, Silvia Parolo, Michael Monine, Xiao Tong, Satish Eraly, Eric Masson, Toby Ferguson, Alexander McCampbell, Danielle Graham, Enrico Domenici, Ivan Nestorov, Luca Marchetti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 4, Pp 447-457 (2022)
Abstract Neurofilaments (Nfs) are the major structural component of neurons. Their role as a potential biomarker of several neurodegenerative diseases has been investigated in past years with promising results. However, even under physiological condi
Externí odkaz:
https://doaj.org/article/de1ae59bb53d404daed33a212cd550f8
Autor:
Alessio Paris, Pranami Bora, Silvia Parolo, Drew MacCannell, Michael Monine, Nick van der Munnik, Xiao Tong, Satish Eraly, Zdenek Berger, Danielle Graham, Toby Ferguson, Enrico Domenici, Ivan Nestorov, Luca Marchetti
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:196-206
Phosphorylated neurofilament heavy subunit (pNfH) has been recently identified as a promising biomarker of disease onset and treatment efficacy in spinal muscular atrophy (SMA). This study introduces a quantitative systems pharmacology model represen
Autor:
Michael Benatar, Joanne Wuu, Peter M. Andersen, Robert C. Bucelli, Jinsy A. Andrews, Markus Otto, Nita A. Farahany, Elizabeth A. Harrington, Weiping Chen, Adele A. Mitchell, Toby Ferguson, Sheena Chew, Liz Gedney, Sue Oakley, Jeong Heo, Sowmya Chary, Laura Fanning, Danielle Graham, Peng Sun, Yingying Liu, Janice Wong, Stephanie Fradette
Despite extensive research, amyotrophic lateral sclerosis (ALS) remains a progressive and invariably fatal neurodegenerative disease. Limited knowledge of the underlying causes of ALS has made it difficult to target upstream biological mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2141520e84778c486c10046b7ad1a18c
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200431
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200431
Autor:
Varant Kupelian, Emma Viscidi, Susan Hall, Li Li, Susan Eaton, Anne Dilley, Nicolas Currier, Toby Ferguson, Laura Fanning
Publikováno v:
Neurology: Clinical Practice. 13:e200110
Background and ObjectivesReduced mobility in patients with amyotrophic lateral sclerosis (ALS) is hypothesized to increase the risk of venous thromboembolism (VTE). A few small, single-center studies have investigated the risk of VTE in patients with
Autor:
Michael Benatar, Joanne Wuu, Peter M. Andersen, Robert C. Bucelli, Jinsy A. Andrews, Markus Otto, Nita A. Farahany, Elizabeth A. Harrington, Weiping Chen, Adele A. Mitchell, Toby Ferguson, Sheena Chew, Liz Gedney, Sue Oakley, Jeong Heo, Sowmya Chary, Laura Fanning, Danielle Graham, Peng Sun, Yingying Liu, Janice Wong, Stephanie Fradette
Publikováno v:
Neurotherapeutics. 19:1686-1686
Autor:
Alexander J, Cammack, Nazem, Atassi, Theodore, Hyman, Leonard H, van den Berg, Matthew, Harms, Robert H, Baloh, Robert H, Brown, Michael A, van Es, Jan H, Veldink, Balint S, de Vries, Jeffrey D, Rothstein, Caroline, Drain, Jennifer, Jockel-Balsarotti, Amber, Malcolm, Sonia, Boodram, Amber, Salter, Nicholas, Wightman, Hong, Yu, Alexander V, Sherman, Thomas J, Esparza, Diane, McKenna-Yasek, Margaret A, Owegi, Catherine, Douthwright, Alexander, McCampbell, Toby, Ferguson, Carlos, Cruchaga, Merit, Cudkowicz, Timothy M, Miller
Publikováno v:
Neurology
OBJECTIVE: To define the natural history of the C9orf72 amyotrophic lateral sclerosis (C9ALS) patient population, develop disease biomarkers, and characterize patient pathologies. METHODS: We prospectively collected clinical and demographic data from
Publikováno v:
The Journal of invasive cardiology. 18(12)
We report on 2 patients with cerebrovascular events associated with sexual activity and PFO who subsequently underwent endovascular patent foramen ovale (PFO) closure. The concurrence of sexual activity (a Valsalva equivalent) at symptom onset, toget
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