Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Toby Aicher"'
Autor:
Julia Roider, Takashi Maehara, Abigail Ngoepe, Duran Ramsuran, Maximilian Muenchhoff, Emily Adland, Toby Aicher, Samuel W. Kazer, Pieter Jooste, Farina Karim, Warren Kuhn, Alex K. Shalek, Thumbi Ndung'u, Lynn Morris, Penny L. Moore, Shiv Pillai, Henrik Kløverpris, Philip Goulder, Alasdair Leslie
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Broadly neutralizing antibodies (bnAbs) against HIV-1 are an effective means of preventing transmission. To better understand the mechanisms by which HIV-specific bnAbs naturally develop, we investigated blood and lymphoid tissue in pediatric infecti
Externí odkaz:
https://doaj.org/article/c66447ad8ffe40e48105ac1cf348eb35
Autor:
Samuel W. Kazer, Alex K. Shalek, Mary Dong, J. Christopher Love, Sarah K. Nyquist, Shaina L. Carroll, Alasdair Leslie, Amber Moodley, Jose Ordovas-Montanes, Toby Aicher, Emily B. Wong, Krista L. Dong, Zaza M. Ndhlovu, Carly G. K. Ziegler, Vincent N. Miao, Nasreen Ismail, Thumbi Ndung'u, Daniel M. Muema, Ang A. Tu, Bruce D. Walker, Bonnie Berger
Publikováno v:
Nature Medicine
Nat Med
Nat Med
Cellular immunity is critical for controlling intracellular pathogens, but individual cellular dynamics and cell–cell cooperativity in evolving human immune responses remain poorly understood. Single-cell RNA-sequencing (scRNA-seq) represents a pow
Autor:
James W. Hicks, Grinu Mathew, Molly Hammell, Naishitha Anaparthy, Ami Patel, Toby Aicher, Yu-Jui Ho, David Molik
Publikováno v:
Genome Research. 28:1353-1363
Single-cell RNA-seq's (scRNA-seq) unprecedented cellular resolution at a genome-wide scale enables us to address questions about cellular heterogeneity that are inaccessible using methods that average over bulk tissue extracts. However, scRNA-seq dat
Autor:
Shiv Pillai, Jolan E. Walter, Jocelyn R. Farmer, Robert E. Gerszten, Hugues Allard-Chamard, Sara Barmettler, Samuel J.H. Murphy, Maimuna Ahmad, Vinay Mahajan, Mark D. Benson, Toby Aicher, Na Sun, Musie Ghebremichael, Alex K. Shalek, Grace J. Yuen, Facundo D. Batista, Alice Bertocchi, Johan Arnold, Jordan Morningstar
Publikováno v:
Sci Signal
Transitional B cells must actively undergo selection for self-tolerance before maturing into their resting follicular B cell successors. We found that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice. In follic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2788d61f5921365480a902dd9bf8faa1
https://europepmc.org/articles/PMC7301641/
https://europepmc.org/articles/PMC7301641/
Autor:
Alex K. Shalek, Emily B. Wong, Zaza M. Ndhlovu, Sarah K. Nyquist, Shaina L. Carroll, Krista L. Dong, Amber Moodley, Daniel M. Muema, Bruce D. Walker, Mary Dong, Carly G. K. Ziegler, Jose Ordovas-Montanes, Nasreen Ismail, Thumbi Ndung'u, Toby Aicher, Samuel W. Kazer
Cellular immunity is critical for controlling intracellular pathogens, but the dynamics and cooperativity of the evolving host response to infection are not well defined. Here, we apply single-cell RNA-sequencing to longitudinally profile pre- and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c930c532cc5a14a3e093ec20a718a6
Autor:
Naishitha Anaparthy, Ami Patel, Toby Aicher, David Molik, James W. Hicks, Yu-Jui Ho, Molly Hammell
Single-cell RNA-Seq’s (scRNA-Seq) unprecedented cellular resolution at a genome wide scale enables us to address questions about cellular heterogeneity that are inaccessible using methods that average over bulk tissue extracts. However, scRNA-Seq d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5935e112c2a9beba5eaa4cbf124f75db
https://doi.org/10.1101/239319
https://doi.org/10.1101/239319
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 8, p e1005606 (2017)
PLoS Computational Biology
PLoS Computational Biology
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