Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tobit D. Steinmetz"'
Autor:
Tobit D. Steinmetz, Liseth de Wolff, Janneke H. Terpstra, Annie Visser, Hendrika Bootsma, Frans G.M. Kroese, Gwenny M. Verstappen
Publikováno v:
Clinical and Experimental Rheumatology, 40(12), 2338-2343. CLINICAL & EXPER RHEUMATOLOGY
Objective The peripheral lymphocyte compartment of patients with primary Sjögren’s syndrome (pSS) differs strongly from healthy individuals. Whether this altered lymphocyte composition also changes abnormally during immune reactions, especially by
Autor:
Tobit D, Steinmetz, Gwenny M, Verstappen, Sebastian R, Schulz, Liseth, de Wolff, Rick, Wilbrink, Annie, Visser, Janneke, Terpstra, Hendrika, Bootsma, Frans G M, Kroese
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
B cell hyperactivity plays an important role in primary Sjögren's syndrome (pSS). To better understand the B cell effector branch, namely antibody-secreting cells (ASC; plasmablasts and plasma cells) in pSS, this study examines abundance, maturation
Autor:
Tobit D. Steinmetz, Lena Reimann, Sebastian R. Schulz, Sophia Urbanczyk, Jana Thomas, Ann-Kathrin Himmelreich, Florian Golombek, Kathrin Castiglione, Susanne Brodesser, Bettina Warscheid, Dirk Mielenz
The autophagy-flux-promoting protein TFG (Trk-fused gene) is up-regulated during B cell differentiation into plasma cells and supports survival of CH12 B cells. We hypothesized that quantitative proteomics analysis of CH12tfgKO B cells with intact or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4d6aa812b0488cc56bae1d9b78d141
https://doi.org/10.1101/2022.09.01.506221
https://doi.org/10.1101/2022.09.01.506221
Autor:
Tobit D. Steinmetz, Gwenny M. Verstappen, Sebastian R. Schulz, Liseth de Wolff, Rick Wilbrink, Annie Visser, Janneke Terpstra, Hendrika Bootsma, Frans G.M. Kroese
Publikováno v:
Arthritis and Rheumatology. Wiley
Objective: B cell hyperactivity plays an important role in primary Sjögren's syndrome (SS). We undertook this study to better understand the B cell effector branch, namely antibody-secreting cells (ASCs) in primary SS, and to examine the quantity, m
Autor:
Jens Wittner, Sebastian R. Schulz, Tobit D. Steinmetz, Johannes Berges, Manuela Hauke, William M. Channell, Adam F. Cunningham, Anja E. Hauser, Andreas Hutloff, Dirk Mielenz, Hans-Martin Jäck, Wolfgang Schuh
Krüppel-like factor 2 (KLF2) is a potent regulator of lymphocyte differentiation, activation and migration. However, its functional role in adaptive and humoral immunity remains elusive. Therefore, by using mice with a B cell-specific deletion of KL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b55fa3ee051643afbddf1cca5eba11
https://pub.uni-bielefeld.de/record/2969003
https://pub.uni-bielefeld.de/record/2969003
Autor:
Sophia Urbanczyk, Olivier R. Baris, Jörg Hofmann, R. Verena Taudte, Naïg Guegen, Florian Golombek, Kathrin Castiglione, Xianyi Meng, Aline Bozec, Jana Thomas, Leonie Weckwerth, Dimitrios Mougiakakos, Sebastian R. Schulz, Wolfgang Schuh, Ursula Schlötzer-Schrehardt, Tobit D. Steinmetz, Susanne Brodesser, Rudolf J. Wiesner, Dirk Mielenz
Publikováno v:
Cell Reports
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
Cell Reports, 2022, 39 (10), pp.110912. ⟨10.1016/j.celrep.2022.110912⟩
International audience; To elucidate the function of oxidative phosphorylation (OxPhos) during B cell differentiation, we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expressi