Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tobias Wimmer"'
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230344 (2020)
In age-related macular degeneration (AMD) or diabetic retinopathy (DR), hypoxia and inflammatory processes lead to an upregulation of the vascular endothelial growth factor (VEGF) expression and thereby to pathological neovascularisation with incorre
Externí odkaz:
https://doaj.org/article/69873a07f14d48eab2dc4d6273aebee2
Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments
Autor:
Mert Yanik, Surya Prakash Goud Ponnam, Tobias Wimmer, Lennart Trimborn, Carina Müller, Isabel Gambert, Johanna Ginsberg, Annabella Janise, Janina Domicke, Wolfgang Wende, Birgit Lorenz, Knut Stieger
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 407-415 (2018)
Common genome-editing strategies are either based on non-homologous end joining (NHEJ) or, in the presence of a template DNA, based on homologous recombination with long (homology-directed repair [HDR]) or short (microhomology-mediated end joining [M
Externí odkaz:
https://doaj.org/article/76e917f45ad34e0781daf6872d2e9526
Autor:
Kathrin Ganzhorn, Tobias Wimmer, Joel Cramer, Richard Schlitz, Stephan Geprägs, Gerhard Jakob, Rudolf Gross, Hans Huebl, Mathias Kläui, Sebastian T. B. Goennenwein
Publikováno v:
AIP Advances, Vol 7, Iss 8, Pp 085102-085102-7 (2017)
We study the transport of thermally excited non-equilibrium magnons through the ferrimagnetic insulator YIG using two electrically isolated Pt strips as injector and detector. The diffusing magnons induce a non-local inverse spin Hall voltage in the
Externí odkaz:
https://doaj.org/article/67dbf16441b6440a9e5516f9d748b574
Publikováno v:
Sensors, Vol 17, Iss 1, p 145 (2017)
In this paper we describe a two-component BRET (bioluminescence resonance energy transfer)-based method to detect vascular endothelial growth factor (VEGF) molecules in unknown samples as the basis for subsequent in vivo use. A luminescent VEGF bindi
Externí odkaz:
https://doaj.org/article/7e636e1934994a75a57f15554d364b27
Publikováno v:
Nucleic Acid Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be55597e855e2a094d811855d664b101
https://doi.org/10.1089/nat.2022.0037
https://doi.org/10.1089/nat.2022.0037
A Bioluminescence Resonance Energy Transfer–Based Reporter System: Characterization and Applications
Autor:
Vincent Moeschl, Knut Stieger, Christian Thiel, Philip Kleekamp, Dileep Bonthu, Matthew Ellinwood, Tobias Wimmer, Lyubomyr Lytvynchuk
Publikováno v:
The CRISPR Journal. 4:884-895
Genome editing strategies and DNA repair research need powerful analytical tools. We generated a bioluminescence resonance energy transfer (BRET)-based reporter for the quantification of indel frequencies induced by DNA repair. The BRET reporter, exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae5df1d19c802022540b8a6af5d780f
https://doi.org/10.1089/crispr.2021.0023
https://doi.org/10.1089/crispr.2021.0023
Autor:
Brigitte, Müller, Franziska, Serafin, Leonie Luise, Laucke, Wilhelm, Rheinhard, Tobias, Wimmer, Knut, Stieger
Publikováno v:
Investigative Opthalmology & Visual Science. 63:22
To characterize the spatial distribution of the DNA-double strand break-repair protein Ku80 in the murine retina. Even though robust data exist on the complexity of DNA repair mechanisms in dividing cells in vitro, almost nothing is known about it in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c48c233041e4ceae0df3456fc5c3992
https://doi.org/10.1167/iovs.63.6.22
https://doi.org/10.1167/iovs.63.6.22
Autor:
Annabella Janise-Libawski, Stefan Hadzic, Elsa Tadele Roxlau, Shaowei Li, Feng Wang, Norbert Weissmann, Knut Stieger, Bo Lei, Tobias Wimmer, Baerbel Fuehler
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Abstract Cigarette smoke has been identified as a major risk factor for the development of age-related macular degeneration (AMD). As an alternative to conventional cigarettes (C-cigarette), electronic cigarettes (E-cigarette) have been globally prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df2f15502676425f3069566b57564db
https://doi.org/10.21203/rs.3.rs-233889/v1
https://doi.org/10.21203/rs.3.rs-233889/v1
Autor:
Janine Gückelhorn, Akashdeep Kamra, Tobias Wimmer, Matthias Opel, Stephan Geprägs, Rudolf Gross, Hans Huebl, Matthias Althammer
Antiferromagnetic materials host pairs of spin-up and spin-down magnons which can be described in terms of a magnonic pseudospin. The close analogy between this magnonic pseudospin systems and that of electronic charge carriers led to the prediction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a49b5502bfc72a784b6e1120560f7a3
Autor:
Tobias Wimmer, Matthias Opel, Stephan Geprägs, Hubert Ebert, Sebastian Wimmer, Janine Gückelhorn, Hans Huebl, Rudolf Gross, Matthias Althammer, Sergiy Mankovsky
We demonstrate the low temperature suppression of the platinum (Pt) spin Nernst angle in bilayers consisting of the antiferromagnetic insulator hematite ($\alpha$-Fe$_2$O$_3$) and Pt upon measuring the transverse spin Nernst magnetothermopower (TSNM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e0073f973c27fd0634125f98cfb641