Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tobias Van Bremen"'
Autor:
Benjamin Krämer, Ansel P. Nalin, Feiyang Ma, Sarah Eickhoff, Philipp Lutz, Sonia Leonardelli, Felix Goeser, Claudia Finnemann, Gudrun Hack, Jan Raabe, Michael ToVinh, Sarah Ahmad, Christoph Hoffmeister, Kim M. Kaiser, Steffen Manekeller, Vittorio Branchi, Tobias Bald, Michael Hölzel, Robert Hüneburg, Hans Dieter Nischalke, Alexander Semaan, Bettina Langhans, Dominik J. Kaczmarek, Brooke Benner, Matthew R. Lordo, Jesse Kowalski, Adam Gerhardt, Jörg Timm, Marieta Toma, Raphael Mohr, Andreas Türler, Arthur Charpentier, Tobias van Bremen, Georg Feldmann, Arne Sattler, Katja Kotsch, Ali T. Abdallah, Christian P. Strassburg, Ulrich Spengler, William E. Carson, III, Bethany L. Mundy-Bosse, Matteo Pellegrini, Timothy E. O’Sullivan, Aharon G. Freud, Jacob Nattermann
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111937- (2023)
Summary: Group 1 innate lymphoid cells (ILCs) comprise a heterogeneous family of cytotoxic natural killer (NK) cells and ILC1s. We identify a population of “liver-type” ILC1s with transcriptional, phenotypic, and functional features distinct from
Externí odkaz:
https://doaj.org/article/0084e5451ed64fc0b420c8bfd7ffa888
Autor:
Benjamin Krämer, Felix Goeser, Philipp Lutz, Andreas Glässner, Christoph Boesecke, Carolynne Schwarze-Zander, Dominik Kaczmarek, Hans Dieter Nischalke, Vittorio Branchi, Steffen Manekeller, Robert Hüneburg, Tobias van Bremen, Tobias Weismüller, Christian P Strassburg, Jürgen K Rockstroh, Ulrich Spengler, Jacob Nattermann
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006373 (2017)
Innate lymphocyte cells (ILCs), a novel family of innate immune cells are considered to function as key orchestrators of immune defences at mucosal surfaces and to be crucial for maintaining an intact intestinal barrier. Accordingly, first data sugge
Externí odkaz:
https://doaj.org/article/4980fba5cb67458d9ba441fe0f4c5a4a
Autor:
Sven Perner, Lynn E. Heasley, Antonio Jimeno, Aik-Choon Tan, Jihye Kim, Andreas Schroeck, Friedrich Bootz, Tobias Van Bremen, Fred R. Hirsch, Justin R. Eagles, Emily K. Kleczko, Wenzel Vogel, Diana Boehm, Robert Kirsten, Carsten Golletz, Antonia Göke, Brigitte Lankat-Buttgereit, Anne von Maessenhausen, Maike Bode, Rakesh Sharma, Petros Yoon, Lindsay A. Marek, Trista K. Hinz, Alina Franzen, Friederike Göke
Purpose: FGFR1 copy-number gain (CNG) occurs in head and neck squamous cell cancers (HNSCC) and is used for patient selection in FGFR-specific inhibitor clinical trials. This study explores FGFR1 mRNA and protein levels in HNSCC cell lines, primary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bda53d4019a9c42e488c2a7b8d21960
https://doi.org/10.1158/1078-0432.c.6524013
https://doi.org/10.1158/1078-0432.c.6524013
Autor:
Sven Perner, Lynn E. Heasley, Antonio Jimeno, Aik-Choon Tan, Jihye Kim, Andreas Schroeck, Friedrich Bootz, Tobias Van Bremen, Fred R. Hirsch, Justin R. Eagles, Emily K. Kleczko, Wenzel Vogel, Diana Boehm, Robert Kirsten, Carsten Golletz, Antonia Göke, Brigitte Lankat-Buttgereit, Anne von Maessenhausen, Maike Bode, Rakesh Sharma, Petros Yoon, Lindsay A. Marek, Trista K. Hinz, Alina Franzen, Friederike Göke
Figure S6. Correlation of HPV-expression and FGFR1 mRNA expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3f3bdb5a8fddfbc8359f71b3ed198f
https://doi.org/10.1158/1078-0432.22458654
https://doi.org/10.1158/1078-0432.22458654
Autor:
Sven Perner, Lynn E. Heasley, Antonio Jimeno, Aik-Choon Tan, Jihye Kim, Andreas Schroeck, Friedrich Bootz, Tobias Van Bremen, Fred R. Hirsch, Justin R. Eagles, Emily K. Kleczko, Wenzel Vogel, Diana Boehm, Robert Kirsten, Carsten Golletz, Antonia Göke, Brigitte Lankat-Buttgereit, Anne von Maessenhausen, Maike Bode, Rakesh Sharma, Petros Yoon, Lindsay A. Marek, Trista K. Hinz, Alina Franzen, Friederike Göke
Table S1. The panel of HNSCC PDXs was submitted to FGFR1 gene copy number (GCN) by CISH and mRNA levels by in situ hybridization (ISH) assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1288d5c5aa8455fb9508f9a1f6fc78b8
https://doi.org/10.1158/1078-0432.22458651.v1
https://doi.org/10.1158/1078-0432.22458651.v1
Autor:
Petros Yoon, Trista K. Hinz, Anne Von Maessenhausen, Friedrich Bootz, Emily K. Kleczko, Tobias van Bremen, Antonio Jimeno, Lindsay Marek, Diana Boehm, Rakesh Sharma, Robert Kirsten, Justin R. Eagles, Alina Franzen, Friederike Göke, Maike Bode, Aik Choon Tan, Brigitte Lankat-Buttgereit, Wenzel Vogel, Carsten Golletz, Fred R. Hirsch, Andreas Schroeck, Jihye Kim, Lynn E. Heasley, Antonia Göke, Sven Perner
Publikováno v:
Clinical Cancer Research. 21:4356-4364
Purpose: FGFR1 copy-number gain (CNG) occurs in head and neck squamous cell cancers (HNSCC) and is used for patient selection in FGFR-specific inhibitor clinical trials. This study explores FGFR1 mRNA and protein levels in HNSCC cell lines, primary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af0c9b1df054d714119d28a2d0197e7
https://doi.org/10.1158/1078-0432.ccr-14-3357
https://doi.org/10.1158/1078-0432.ccr-14-3357
Publikováno v:
Journal of muscle research and cell motility. 38(3-4)
Damage of peripheral nerves results in paralysis of skeletal muscle. Currently, the only treatment option to restore proper function is electrical stimulation of the innervating nerve or of the skeletal muscles directly. However this approach has low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbc1917df62301076e38fddf96fecce
https://pubmed.ncbi.nlm.nih.gov/28918572
https://pubmed.ncbi.nlm.nih.gov/28918572
Autor:
Jürgen K. Rockstroh, Dominik J. Kaczmarek, Christoph Boesecke, Felix Goeser, Tobias van Bremen, Robert Hüneburg, Ulrich Spengler, Carolynne Schwarze-Zander, Steffen Manekeller, Vittorio Branchi, Christian P. Strassburg, Andreas Glässner, Benjamin Krämer, Tobias J. Weismüller, Hans Dieter Nischalke, Jacob Nattermann, Philipp Lutz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006373 (2017)
PLoS Pathogens
PLoS Pathogens
Innate lymphocyte cells (ILCs), a novel family of innate immune cells are considered to function as key orchestrators of immune defences at mucosal surfaces and to be crucial for maintaining an intact intestinal barrier. Accordingly, first data sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19bd24316798c36c927e82b57b6be5f
https://doaj.org/article/4980fba5cb67458d9ba441fe0f4c5a4a
https://doaj.org/article/4980fba5cb67458d9ba441fe0f4c5a4a
Autor:
Maike Bode, Patrick L. Wagner, Claudia Lengerke, Diana Boehm, Rakesh Sharma, Wenzel Vogel, Alina Franzen, Jutta Kirfel, Tobias van Bremen, Lynn E. Heasley, Friedrich Bootz, Sven Perner, Friederike Göke, Diane Goltz, Antonia Göke, Glen Kristiansen, Andreas Schröck, Robert Kirsten
Publikováno v:
Modern Pathology. 26:1298-1306
Recently, we characterized fibroblast growth factor receptor 1 amplification as a target for a rational therapy in lung squamous cell carcinoma. Patients harboring this genetic event are currently eligible for treatment with antifibroblast growth fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61182040d7ceecbdf99ae5dd47be525d
https://doi.org/10.1038/modpathol.2013.58
https://doi.org/10.1038/modpathol.2013.58
Autor:
Tobias van Bremen, Thorsten Send, Philipp Sasse, Christoph C. Vogt, Tobias Bruegmann, Bernd K. Fleischmann
Publikováno v:
Nature Communications
Optogenetic stimulation allows activation of cells with high spatial and temporal precision. Here we show direct optogenetic stimulation of skeletal muscle from transgenic mice expressing the light-sensitive channel Channelrhodopsin-2 (ChR2). Largest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b266288137b993cbd76a4e71b7e64c42
http://europepmc.org/articles/PMC4475236
http://europepmc.org/articles/PMC4475236