Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tobias V Lanz"'
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Here, we offer a roadmap for what might be studied next in understanding how EBV triggers MS. We focus on two areas: The first area concerns the molecular mechanisms underlying how clonal antibody in the CSF emanates in widespread molecular
Externí odkaz:
https://doaj.org/article/78ed79c9f8d147ca865e0009cc6a9861
Autor:
Alexander Lercher, Alexandra M Popa, Csilla Viczenczova, Lindsay Kosack, Kristaps Klavins, Benedikt Agerer, Christiane A Opitz, Tobias V Lanz, Michael Platten, Andreas Bergthaler
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008973 (2020)
The liver is a central regulator of metabolic homeostasis and serum metabolite levels. Hepatocytes are the functional units of the liver parenchyma and not only responsible for turnover of biomolecules but also act as central immune signaling platfor
Externí odkaz:
https://doaj.org/article/c0014948cc8a407aa9e92e448df475d8
Autor:
Jana K. Sonner, Melanie Keil, Maren Falk-Paulsen, Neha Mishra, Ateequr Rehman, Magdalena Kramer, Katrin Deumelandt, Julian Röwe, Khwab Sanghvi, Lara Wolf, Anna von Landenberg, Hendrik Wolff, Richa Bharti, Iris Oezen, Tobias V. Lanz, Florian Wanke, Yilang Tang, Ines Brandao, Soumya R. Mohapatra, Lisa Epping, Alexandra Grill, Ralph Röth, Beate Niesler, Sven G. Meuth, Christiane A. Opitz, Jürgen G. Okun, Christoph Reinhardt, Florian C. Kurschus, Wolfgang Wick, Helge B. Bode, Philip Rosenstiel, Michael Platten
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Food intake shapes intestinal microbiome composition, which in turn shapes adaptive immune responses. Here the authors show that dietary tryptophan restriction (DTR) protects mice from subsequent autoimmune neuropathology challenge by altering intest
Externí odkaz:
https://doaj.org/article/4ad85525c9344809af644aa890fe63d4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
High-throughput single-cell technologies have recently emerged as essential tools in biomedical research with great potential for clinical pathology when studying liquid and solid biopsies. We provide an update on current single-cell methods in cereb
Externí odkaz:
https://doaj.org/article/a084c53696e24038886822e54e6ab563
Autor:
Alejandro M. Gomez, R. Camille Brewer, Jae-Seung Moon, Suman Acharya, Sarah Kongpachith, Qian Wang, Shaghayegh Jahanbani, Heidi H. Wong, Tobias V. Lanz, Zelda Z. Love, Gundula Min-Oo, Anita Niedziela-Majka, William H. Robinson
Anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA) and have long been considered to contribute to pathogenesis. In this study, we sequenced the plasmablast antibody repertoires of RA patients and functionally ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2342c6dd5b03f7fbedc2f66709236c7
https://doi.org/10.1101/2023.03.08.531560
https://doi.org/10.1101/2023.03.08.531560
Autor:
Tobias V Lanz, R Camille Brewer, Peggy P Ho, Kevin M Jude, Daniel Fernandez, Jae-Seung Moon, Ricardo A Fernandes, Alejandro M Gomez, Gabriel-Stefan Nadj, Christopher M Bartley, Ryan D Schubert, Isobel A Hawes, Sara E Vazquez, Manasi Iyer, J Bradley Zuchero, Bianca Teegen, Jeffrey E Dunn, Christopher B Lock, Lucas B Kipp, Victoria C Cotham, Beatrix M Ueberheide, Blake T Aftab, Mark S Anderson, Joseph L DeRisi, Michael R Wilson, Rachael JM Bashford-Rogers, Michael Platten, K Christopher Garcia, Lawrence Steinman, William H Robinson
Publikováno v:
Nature
Nature, vol 603, iss 7900
Nature, vol 603, iss 7900
Multiple sclerosis (MS) is a heterogenous autoimmune disease in which autoreactive lymphocytes attack the myelin sheath of the central nervous system. B lymphocytes in the cerebrospinal fluid (CSF) of patients with MS contribute to inflammation and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2318b2d41a42f0170e92995f810de60
https://doi.org/10.1038/s41586-022-04432-7
https://doi.org/10.1038/s41586-022-04432-7
Autor:
R. Camille Brewer, Tobias V. Lanz, Caryn R. Hale, Gregory D. Sepich-Poore, Cameron Martino, Austin D. Swafford, Thomas S. Carroll, Sarah Kongpachith, Lisa K. Blum, Serra E. Elliott, Nathalie E. Blachere, Salina Parveen, John Fak, Vicky Yao, Olga Troyanskaya, Mayu O. Frank, Michelle S. Bloom, Shaghayegh Jahanbani, Alejandro M. Gomez, Radhika Iyer, Nitya S. Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B. Kelmenson, Qian Wang, Heidi Wong, Holly L. Torres, Mark Wiesen, Dana T. Graves, Kevin D. Deane, V. Michael Holers, Rob Knight, Robert B. Darnell, William H. Robinson, Dana E. Orange
Publikováno v:
Science Translational Medicine. 15
Periodontal disease is more common in individuals with rheumatoid arthritis (RA) who have detectable anti-citrullinated protein antibodies (ACPAs), implicating oral mucosal inflammation in RA pathogenesis. Here, we performed paired analysis of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe98296461d8cd7e49e173f6484eb349
https://doi.org/10.1126/scitranslmed.abq8476
https://doi.org/10.1126/scitranslmed.abq8476
Publikováno v:
Research square.
Since early December 2021, the omicron variant has posed additional challenges to the world-wide management of the SARS-CoV-2 pandemic. Immune evasion is a key factor for its increased transmissibility. While serological studies have measured levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723785153923cf0d044b3aa99ea9c7bd
https://pubmed.ncbi.nlm.nih.gov/35441169
https://pubmed.ncbi.nlm.nih.gov/35441169
Autor:
Rittika Chunder, Alicia Weier, Hannah Mäurer, Nicolas Luber, Michael Enders, Gabriele Luber, Thorsten Heider, Alfred Spitzer, Sabine Tacke, Janine Becker-Gotot, Christian Kurts, Radhika Iyer, Peggy P. Ho, William H. Robinson, Tobias V. Lanz, Stefanie Kuerten
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(10)
Multiple sclerosis (MS) is a neuroinflammatory demyelinating disease of the central nervous system (CNS) with a high socioeconomic relevance. The pathophysiology of MS, which is both complex and incompletely understood, is believed to be influenced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb572e5f27d93aa14f5fea77c401f965
https://pubmed.ncbi.nlm.nih.gov/35235454
https://pubmed.ncbi.nlm.nih.gov/35235454
Autor:
Tobias V. Lanz, Lauren J. Lahey, Nitya S. Ramadoss, William H. Robinson, Shaghayegh Jahanbani, R. Camille Brewer
Publikováno v:
Nat Immunol
The first ever US Food and Drug Administration-approved messenger RNA vaccines are highly protective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1-3. However, the contribution of each dose to the generation of antibodies again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160104fb1d1764a7678db35115bbb76f
https://europepmc.org/articles/PMC8776031/
https://europepmc.org/articles/PMC8776031/