Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tobias Tekath"'
Autor:
Katharina Thomas, Lisa Zondler, Nadine Ludwig, Marina Kardell, Corinna Lüneburg, Katharina Henke, Sina Mersmann, Andreas Margraf, Tilmann Spieker, Tobias Tekath, Ana Velic, Richard Holtmeier, Juliane Hermann, Vera Jankowski, Melanie Meersch, Dietmar Vestweber, Martin Westphal, Johannes Roth, Michael A. Schäfers, John A. Kellum, Clifford A. Lowell, Jan Rossaint, Alexander Zarbock
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2022)
Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine AKI model induced by ischemia/reperfusion injury (IRI), we show that glutamine significantly
Externí odkaz:
https://doaj.org/article/30ea337b9c5d4c7ea8eab77560c841db
Autor:
Jan Rossaint, Melanie Meersch, Katharina Thomas, Sina Mersmann, Martin Lehmann, Jennifer Skupski, Tobias Tekath, Peter Rosenberger, John A. Kellum, Hermann Pavenstädt, Alexander Zarbock
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Acute kidney injury increases morbidity and mortality, and previous studies have shown that remote ischemic preconditioning (RIPC) reduces the risk of acute kidney injury after cardiac surgery. RIPC increases urinary high mobility group box protein-1
Externí odkaz:
https://doaj.org/article/5b4605dd23ba458f874aefa40181f27b
Autor:
Sara Di Persio, Tobias Tekath, Lara Marie Siebert-Kuss, Jann-Frederik Cremers, Joachim Wistuba, Xiaolin Li, Gerd Meyer zu Hörste, Hannes C.A. Drexler, Margot Julia Wyrwoll, Frank Tüttelmann, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Sandra Laurentino, Nina Neuhaus
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100395- (2021)
Summary: Despite the high incidence of male infertility, only 30% of infertile men receive a causative diagnosis. To explore the regulatory mechanisms governing human germ cell function in normal and impaired spermatogenesis (crypto), we performed si
Externí odkaz:
https://doaj.org/article/69ff66c3292144e7a730709ca93d00b8
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190421 (2018)
Understanding the effect of cis-regulatory elements (CRE) and clusters of CREs, which are called cis-regulatory modules (CRM), in eukaryotic gene expression is a challenge of computational biology. We developed two programs that allow simple, fast an
Externí odkaz:
https://doaj.org/article/983e159d053e40d19d18d1e1b427f6eb
Autor:
Tobias Tekath, Martin Dugas
Publikováno v:
Bioinformatics
Motivation Each year, the number of published bulk and single-cell RNA-seq datasets is growing exponentially. Studies analyzing such data are commonly looking at gene-level differences, while the collected RNA-seq data inherently represents reads of
Autor:
Alexandra Polakova, Christoph Hudemann, Farzan Solimani, Jakob Matthes, Kamran Ghoreschi, Iris Schäfer, Rüdiger Eming, Michael Hertl, Robert Pollmann, Christian Möbs, Julia Holstein, Dario Didona, Martin Dugas, Tobias Tekath, Carolin Baum, Nicolas Casadei, Wolfgang Pfützner, Katharina Meier, Amir S. Yazdi
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:2358-2369
Background TH2 cells were thought to be a pivotal factor for initiation of the autoimmune blistering disease pemphigus. However, the role of other T-cell subsets in pemphigus pathogenesis remained unclear. Objective We aimed to characterize the exact
Autor:
Lara M Siebert-Kuss, Henrike Krenz, Tobias Tekath, Marius Wöste, Sara Di Persio, Nicole Terwort, Margot J Wyrwoll, Jann-Frederik Cremers, Joachim Wistuba, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Frank Tüttelmann, Jörg Gromoll, Nina Neuhaus, Sandra Laurentino
Publikováno v:
Life science alliance. 6(2)
The process of spermatogenesis—when germ cells differentiate into sperm—is tightly regulated, and misregulation in gene expression is likely to be involved in the physiopathology of male infertility. The testis is one of the most transcriptionall
Autor:
Lara Marie Siebert-Kuss, Henrike Krenz, Tobias Tekath, Marius Wöste, Sara Di Persio, Nicole Terwort, Margot J. Wyrwoll, Jann-Frederik Cremers, Joachim Wistuba, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Frank Tüttelmann, Jörg Gromoll, Nina Neuhaus, Sandra Laurentino
Cell differentiation processes are highly dependent on cell stage-specific gene expression, including timely production of alternatively spliced transcripts. One of the most transcriptionally rich tissues is the testis, where the process of spermatog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25f0a6920bc0e265de91301d45dd04a0
https://doi.org/10.1101/2022.03.22.485121
https://doi.org/10.1101/2022.03.22.485121
Autor:
Virginie Eclache, John Boudjarane, Naïs Prade, Stéphanie Struski, Laetitia Largeaud, Cyril Broccardo, Joop H. Jansen, Christine Terré, Marie-Agnès Collonge-Rame, Pierre-Yves Juvin, Dominique Penther, Stéphanie Lagarde, Antoine Ittel, Véronique Mansat-De Mas, G Ameye, Isabelle Luquet, Marina Lafage-Pochitaloff, Carole Barin, David Rombaut, Bastien Gerby, Carine Gervais, Steven Richebourg, Oliver M. Dovey, Pierre Bories, Christine Lefebvre, Isabelle Radford-Weiss, Audrey Bidet, Isabelle Tigaud, George S. Vassiliou, Benedicte Ribourtout, Tobias Tekath, Michaela Fontenay, Lucienne Michaux, Sylvie Hébrard, Hélène Antoine-Poirel, Laura Jamrog, Vincent Fregona, Nathalie Nadal, Eric Delabesse, Véronique Baccini, Kosuke Yusa
Publikováno v:
Blood Advances, 6, 2, pp. 386-398
Blood Advances
Blood Advances, 6, 386-398
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2021005311⟩
Blood Advances
Blood Advances, 6, 386-398
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2021005311⟩
Key Points We detail at clinical, cytological, cytogenetic, and molecular levels 113 cases of MDS and MDS/MPN with del(11q), a rare recurrent event.CADM1, a tumor suppressor gene identified initially in solid tumors, ATM, CBL, and KMT2A are deleted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a801474f49c15e8392848015e288927
https://repository.ubn.ru.nl/handle/2066/244555
https://repository.ubn.ru.nl/handle/2066/244555
Autor:
Jann-Frederik Cremers, Nina Neuhaus, Joachim Wistuba, Martin Dugas, Xiaolin Li, Frank Tüttelmann, Gerd Meyer zu Hörste, Margot J. Wyrwoll, Sara Di Persio, Hannes C.A. Drexler, Sabine Kliesch, Stefan Schlatt, Sandra Laurentino, Tobias Tekath, Lara Marie Siebert-Kuss
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100395-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Despite the high incidence of male infertility, only 30% of infertile men receive a causative diagnosis. To explore the regulatory mechanisms governing human germ cell function in normal and impaired spermatogenesis (crypto), we performed sin