Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Tobias Sing"'
Autor:
Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 3, p e58 (2007)
HIV-1 cell entry commonly uses, in addition to CD4, one of the chemokine receptors CCR5 or CXCR4 as coreceptor. Knowledge of coreceptor usage is critical for monitoring disease progression as well as for supporting therapy with the novel drug class o
Externí odkaz:
https://doaj.org/article/9696edba78124d35b28644f5d626f5e7
Autor:
Carolina Neu, Christian Beckers, Nadine Frank, Katharina Thomas, Matthias Bartneck, Tim-Philipp Simon, Jana Mossanen, Kimmo Peters, Tobias Singendonk, Lukas Martin, Gernot Marx, Sandra Kraemer, Elisabeth Zechendorf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Sepsis, marked by organ dysfunction, necessitates reliable biomarkers. Ribonuclease inhibitor 1 (RNH1), a ribonuclease (RNase) inhibitor, emerged as a potential biomarker for acute kidney injury and mortality in thoracoabdominal aortic aneur
Externí odkaz:
https://doaj.org/article/74d1435f19a343e8bdda8367b314c237
Publikováno v:
Toxicologic pathology. 49(4)
For decades, it has been postulated that digital pathology is the future. By now it is safe to say that we are living that future. Digital pathology has expanded into all aspects of pathology, including human diagnostic pathology, veterinary diagnost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325075d23eac0f564412b64c75e94be3
https://pubmed.ncbi.nlm.nih.gov/33840332
https://pubmed.ncbi.nlm.nih.gov/33840332
Autor:
Arno Doelemeyer, Thierry Flandre, Vincent Romanet, Alessandro Piaia, Julie Boisclair, Esther Sutter, Kuno Wuersch, Gianluca Santarossa, Holger Hoefling, Tobias Sing, Chandrassegar Saravanan, Pierre Moulin, Oliver C. Turner, Imtiaz Hossain
Publikováno v:
Toxicologic pathology. 49(4)
We introduce HistoNet, a deep neural network trained on normal tissue. On 1690 slides with rat tissue samples from 6 preclinical toxicology studies, tissue regions were outlined and annotated by pathologists into 46 different tissue classes. From the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fa38fd4827f974e39e9918e1611c20
https://pubmed.ncbi.nlm.nih.gov/33653171
https://pubmed.ncbi.nlm.nih.gov/33653171
Autor:
Benjamin Derin, Tobias Singelnstein
Publikováno v:
Verfassungsblog, Iss 2366-7044 (2024)
Als Trägerin des staatlichen Gewaltmonopols ist die Polizei eine Institution, deren Kontrolle im demokratischen Rechtsstaat besondere Bedeutung zukommt. Immer wieder zeigt sich, dass die bestehenden Mechanismen unzulänglich sind, um von Polizist:in
Externí odkaz:
https://doaj.org/article/7d6b57f0393743ffba2b0f44f4f26bf6
Autor:
Tobias Sing, Arno Doelemeyer, Julie Boisclair, Santarossa G, Oliver C. Turner, Chandrassegar Saravanan, Esther Sutter, Imtiaz Hossain, Pierre Moulin, Alessandro Piaia, Holger Hoefling, Kuno Wuersch, Romanet, Thierry Flandre
Deep learning models have been applied on various tissues in order to recognize malignancies. However, these models focus on relatively narrow tissue context or well-defined pathologies. Here, instead of focusing on pathologies, we introduce models c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6cf3ee42cf4cb91979fcee0584ab45
Autor:
Manu M. Sebastian, Tobias Sing, Bhupinder Bawa, Anantharaman Muthuswamy, Tom Forest, Danielle L. Brown, Daniel G. Rudmann, Olulanu H Aina, Brian Knight, Oliver C. Turner, Wanda High, Lauren E. Himmel, Famke Aeffner, Elijah F. Edmondson, Dinesh S. Bangari, Chandrassegar Saravanan, Brieuc Cossic
Publikováno v:
Toxicologic pathology. 48(2)
Toxicologic pathology is transitioning from analog to digital methods. This transition seems inevitable due to a host of ongoing social and medical technological forces. Of these, artificial intelligence (AI) and in particular machine learning (ML) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab406066e2273b8f44ac25804efbd3db
https://pubmed.ncbi.nlm.nih.gov/31645203
https://pubmed.ncbi.nlm.nih.gov/31645203
Autor:
Hannah Espín Grau, Tobias Singelnstein
Publikováno v:
Verfassungsblog, Iss 2366-7044 (2023)
Bereits seit längerer Zeit kommen in (Teilen) der Polizei Techniken der Gewaltanwendung zum Einsatz, die als Schmerzgriffe bezeichnet werden. In der englischsprachigen Debatte werden diese Techniken unter dem Schlagwort „pain compliance“ diskuti
Externí odkaz:
https://doaj.org/article/228affd98b5c42dbb8047ac03dac598a
Autor:
Barbara Nuesslein-Hildesheim, Nigel Graham Cooke, E Wallström, M Saltzman, Anne Gardin, Shifeng Pan, N Wang, A Vitaliti, Martin Traebert, Mara Rosenberg, W J Crumb, Andrea Groenewegen, Nathanael S. Gray, Danilo Guerini, Tobias Sing, Pál Gergely, Volker Brinkmann, J Yang, Klaus Hinterding, O Luttringer, Christian Bruns
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE BAF312 is a next-generation sphingosine 1-phosphate (S1P) receptor modulator, selective for S1P1 and S1P5 receptors. S1P1 receptors are essential for lymphocyte egress from lymph nodes and a drug target in immune-mediated disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd6bd9bc158c3f23950536768418367
https://doi.org/10.1111/j.1476-5381.2012.02061.x
https://doi.org/10.1111/j.1476-5381.2012.02061.x
Autor:
Bernard Masquelier, Philippe Flandre, Francesca Ceccherini-Silberstein, Claudia Alteri, Stefano Alcaro, Lucia Parrotta, Ada Bertoli, Giosuè Costa, Federica Forbici, Carlo Federico Perno, Valentina Svicher, Anna Artese, Vincent Calvez, Francesco Ortuso, Tobias Sing, Maria Mercedes Santoro, Diane Descamps, Anne-Geneviève Marcelin
Publikováno v:
ChemMedChem; Vol 6
An integrated computational and statistical approach was used to determine the association of non-nucleoside reverse transcriptase inhibitors (NNRTIs) nevirapine, efavirenz and etravirine with resistance mutations that cause therapeutic failure and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8352a73f3d3db05c83899ca85be9e1