Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tobias Sargeant"'
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1007603 (2020)
Analysing multiple cancer samples from an individual patient can provide insight into the way the disease evolves. Monitoring the expansion and contraction of distinct clones helps to reveal the mutations that initiate the disease and those that driv
Externí odkaz:
https://doaj.org/article/d340fd5794ea4940b93de0376ed72bed
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72884 (2013)
Accurate quantification of gene expression by qRT-PCR relies on normalization against a consistently expressed control gene. However, control genes in common use often vary greatly between samples, especially in cancer. The advent of Next Generation
Externí odkaz:
https://doaj.org/article/57cea8ce3b4c4ad59eeec2db8db37787
Autor:
Shalin Naik, Luyi Tian, Sara Tomei, Jaring Schreuder, Tom Weber, Daniela Amman-Zalcenstein, Dawn Lin, Jessica Tran, Cindy Audiger, Melanie Bahlo, Mathew Chu, Peter Diakumis, Quentin Gouil, Adrienne Hilton, Andrew Jarratt, Tracy Willson, Lev Kats, Madison kelly, Ee Shan Pang, Meredith O'Keeffe, Timothy Patton, Tobias Sargeant, Shian Su, Philip Hodgkin, Ashley Ng, Matthew Ritchie
Publikováno v:
Experimental Hematology. 100:S92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2257930456c7a8939d741f02202ca5b
https://doi.org/10.1016/j.exphem.2021.12.321
https://doi.org/10.1016/j.exphem.2021.12.321
Autor:
Steven K. Dower, Angela D'Amico, Susan K. Nilsson, Elizabeth A. Kruse, Jessica E. Bolden, Christine Biben, Adriana Baz Morelli, Kerry A. Ramsay, Erin C. Lucas, Douglas J. Hilton, Tracey M. Baldwin, Carolyn A. de Graaf, Sandra Koernig, Tobias Sargeant, Nick Seidenman, Michael J. Wilson, Clare Morgan, Shen Y. Heazlewood, Warren S. Alexander, Yifang Hu, Gordon K. Smyth, Maria Kauppi, Ashley P. Ng, Jarny Choi, Li Wu, Aaron J. Robinson, Kirsten A. Fairfax, Brenda Williams, Marthe C. D'Ombrain
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 571-582 (2016)
Stem Cell Reports
Stem Cell Reports
Summary Hematopoiesis is a multistage process involving the differentiation of stem and progenitor cells into distinct mature cell lineages. Here we present Haemopedia, an atlas of murine gene-expression data containing 54 hematopoietic cell types, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19e75849bfffce6a8359140b23bc594
http://www.sciencedirect.com/science/article/pii/S221367111630131X
http://www.sciencedirect.com/science/article/pii/S221367111630131X
Autor:
Emma C. Josefsson, Samir Taoudi, Warren S. Alexander, Douglas J. Hilton, Tobias Sargeant, Caleb A. Dawson, Kathryn S. Potts
Publikováno v:
Blood. 126:807-816
The thrombopoietic environment of the neonate is established during prenatal life; therefore, a comprehensive understanding of platelet-forming cell development during embryogenesis is critical to understanding the etiology of early-onset thrombocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8791590cee92773703c707ee16886299
https://doi.org/10.1182/blood-2014-12-616607
https://doi.org/10.1182/blood-2014-12-616607
Autor:
Christoffer Flensburg, Tobias Sargeant, Astrid Bosma, Roelof J. C. Kluin, Robby E. Kibbelaar, Mels Hoogendoorn, Warren S. Alexander, Andrew W. Roberts, René Bernards, Daphne de Jong, Ian J. Majewski
Follicular lymphoma (FL) is typically a slow growing cancer that can be effectively treated. Some patients undergo transformation to diffuse large B cell lymphoma (DLBCL), which is frequently resistant to chemotherapy and is generally fatal. Targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5d18ae3bd0cfac5b735f54bc523284
https://doi.org/10.1101/181792
https://doi.org/10.1101/181792
Autor:
Brian T. Wilhelm, Marieke Rozendaal, Sylvie Mader, Vincent-Philippe Lavallée, Dariel Ashton-Beaucage, Josée Hébert, Sébastien Lemieux, Geneviève Boucher, Douglas J. Hilton, Guy Sauvageau, David Laperrière, Tobias Sargeant, Houssam Ismail
Publikováno v:
Nucleic Acids Research
Genome-wide transcriptome profiling has enabled non-supervised classification of tumours, revealing different sub-groups characterized by specific gene expression features. However, the biological significance of these subtypes remains for the most p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e31adfe207c32b164c79d1252b9dae
https://pubmed.ncbi.nlm.nih.gov/28472340
https://pubmed.ncbi.nlm.nih.gov/28472340
Autor:
Marie-Adèle Rajandream, Mandy Sanders, Mark Simmonds, Danielle Walker, S. Sanders, Tobias Mourier, Celine Carret, Al Ivens, Thomas M. Keane, Jaina Mistry, Martin Aslett, Sharon Moule, Douglas Ormond, Tobias Sargeant, Alan W. Thomas, Inna Cherevach, Brian White, Clemens H. M. Kocken, Mary R. Galinski, S. Balasubrammaniam, R. Squares, Arnab Pain, Neil Hall, Alan F. Cowman, Andrew Berry, Stacey A. Lapp, Scott Thurston, Michael A. Quail, Karsten M. Borgwardt, Tim Carver, Nicholas S. Peters, Irmtraud M. Meyer, Frances Smith, Tracey Chillingworth, Taane G. Clark, Eduard Zuiderwijk, Matthew Berriman, Adrian Tivey, Matthias Marti, Chris I. Newbold, C. M. R. Turner, D. Harper, Natasha Larke, Christoph S. Janssen, Bart Barrell, Heidi Hauser, Erica M. Pasini, Carol Churcher, Karen Brooks, Ulrike Böhme, Andrew P. Jackson, Karen Mungall, Robert D. Finn, David Harris
Publikováno v:
Nature, 455
Plasmodium knowlesi is an intracellular malaria parasite whose natural vertebrate host is Macaca fascicularis (the ‘kra’ monkey); however, it is now increasingly recognized as a significant cause of human malaria, particularly in southeast Asia1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024c5eeb1be78d11c86df3f6b1611890
https://ora.ox.ac.uk/objects/uuid:d033391f-dc38-479c-9686-227efaed704c
https://ora.ox.ac.uk/objects/uuid:d033391f-dc38-479c-9686-227efaed704c
Autor:
Paul R. Gilson, Claire M. Fraser-Liggett, John H. Adams, Malcolm J. Gardner, T. Feldblyum, Kobby Essien, Richard M.R. Coulson, Tobias Sargeant, Elisabet Caler, Jonathan Crabtree, Emilio F. Merino, Steven A. Sullivan, Jane M. Carlton, Christian J. Stoeckert, Ian T. Paulsen, Mary R. Galinski, Vish Nene, Michael Korsinczky, Stephen L. Hoffman, Joana C. Silva, Jennifer R. Wortman, Samuel V. Angiuoli, Owen White, Qin Cheng, Stuart A. Ralph, Qinghu Ren, Steven L. Salzberg, Shelby L. Bidwell, Carmen Fernandez-Becerra, Brendan S. Crabb, Simon Kang’a, Hernan Lorenzi, John W. Barnwell, Taco W. A. Kooij, Marcio Massao Yamamoto, Esmeralda V. S. Meyer, Hernando A. del Portillo, Xiang Guo, Paolo Amedeo, Amy H. Gueye
Publikováno v:
Nature. 455:757-763
The human malaria parasite Plasmodium vivax is responsible for 25-40% of the approximately 515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms and often causes relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7525fe47b5411d548964cf03371440f
https://doi.org/10.1038/nature07327
https://doi.org/10.1038/nature07327
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(7)
In a functional genomics screen of mouse embryonic stem cells (ESCs) with nested hemizygous chromosomal deletions, we reveal that ribosomal protein (RP) genes are the most significant haploinsufficient determinants for embryoid body (EB) formation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7822b952a97ec917d09afe1d1395330
https://pubmed.ncbi.nlm.nih.gov/25646475
https://pubmed.ncbi.nlm.nih.gov/25646475