Výsledky vyhledávání - "Tobias S Obermann"

RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork

Autor: Nina B. Liabakk, Geir Slupphaug, Bodil Kavli, Tobias S Obermann, Tobias S. Iveland, Lars Hagen, Edith Buchinger, Per Arne Aas, Finn Lillelund Aachmann

Publikováno v: Nucleic Acids Research

Uracil occurs at replication forks via misincorporation of deoxyuridine monophosphate (dUMP) or via deamination of existing cytosines, which occurs 2–3 orders of magnitude faster in ssDNA than in dsDNA and is 100% miscoding. Tethering of UNG2 to pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1300d8e4bf01fed7c211084f636c6fac
https://pubmed.ncbi.nlm.nih.gov/33784377

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