Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Tobias Rausch"'
Autor:
Wolfram Höps, Tobias Rausch, Michael Jendrusch, Human Genome Structural Variation Consortium (HGSVC), Jan O. Korbel, Fritz J. Sedlazeck
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Modern sequencing technology enables the systematic detection of complex structural variation (SV) across genomes. However, extensive DNA rearrangements arising through a series of mutations, a phenomenon we refer to as serial SV (sSV), rema
Externí odkaz:
https://doaj.org/article/4c219d508eba43c292207434962da475
Autor:
Stephan Krieg, Thomas Rohde, Tobias Rausch, Luise Butthof, Lena Wendler-Link, Christoph Eckert, Kai Breuhahn, Bruno Galy, Jan Korbel, Maximilian Billmann, Marco Breinig, Darjus F. Tschaharganeh
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Somatic copy number alterations are a hallmark of cancer that offer unique opportunities for therapeutic exploitation. Here, we focused on the identification of specific vulnerabilities for tumors harboring chromosome 8p deletions
Externí odkaz:
https://doaj.org/article/d7c5dfffb2304419945cd7a2bce10c8a
Autor:
Christian Bundschuh, Niklas Weidner, Julian Klein, Tobias Rausch, Nayara Azevedo, Anja Telzerow, Katharina Laurence Jost, Paul Schnitzler, Hans-Georg Kräusslich, Vladimir Benes
Publikováno v:
Data in Brief, Vol 55, Iss , Pp 110607- (2024)
In January 2021, Germany commenced surveillance of SARS-CoV-2 variants under the Corona Surveillance Act, which ceased in July 2023. The objective was to bolster pandemic control, as specific alterations in amino acids, particularly within the spike
Externí odkaz:
https://doaj.org/article/3bb6fb62e7fb4925b08fd307708cb32c
Autor:
Tamara Kempter, Paulina Richter-Pechanska, Katarzyna Michel, Tobias Rausch, Büşra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Renate Kirschner-Schwabe, Stefan Koehrer, Jan Korbel, Joachim Kunz, Andreas E Kulozik
Publikováno v:
HemaSphere, Vol 7, p e9493074 (2023)
Externí odkaz:
https://doaj.org/article/77ee918485564004bb875af4218b482e
Autor:
Valentina Spleis, Büşra Erarslan-Uysal, Joachim Kunz, Tobias Rausch, Jan Korbel, Andreas E Kulozik
Publikováno v:
HemaSphere, Vol 7, p e39481d9 (2023)
Externí odkaz:
https://doaj.org/article/ced15f8516d74fa6af7108846ffed049
Autor:
Jiadong Lin, Xiaofei Yang, Walter Kosters, Tun Xu, Yanyan Jia, Songbo Wang, Qihui Zhu, Mallory Ryan, Li Guo, Chengsheng Zhang, Charles Lee, Scott E. Devine, Evan E. Eichler, Kai Ye, Mark B. Gerstein, Ashley D. Sanders, Micheal C. Zody, Michael E. Talkowski, Ryan E. Mills, Jan O. Korbel, Tobias Marschall, Peter Ebert, Peter A. Audano, Bernardo Rodriguez-Martin, David Porubsky, Marc Jan Bonder, Arvis Sulovari, Jana Ebler, Weichen Zhou, Rebecca Serra Mari, Feyza Yilmaz, Xuefang Zhao, PingHsun Hsieh, Joyce Lee, Sushant Kumar, Tobias Rausch, Yu Chen, Zechen Chong, Katherine M. Munson, Mark J.P. Chaisson, Junjie Chen, Xinghua Shi, Aaron M. Wenger, William T. Harvey, Patrick Hansenfeld, Allison Regier, Ira M. Hall, Paul Flicek, Alex R. Hastie, Susan Fairely
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 1, Pp 205-218 (2022)
Complex structural variants (CSVs) are genomic alterations that have more than two breakpoints and are considered as the simultaneous occurrence of simple structural variants. However, detecting the compounded mutational signals of CSVs is challengin
Externí odkaz:
https://doaj.org/article/513b1cf5af894e5190b4427f8d55b1a7
Autor:
Luigi Marongiu, Jonathan J. M. Landry, Tobias Rausch, Mohammed L. Abba, Susanne Delecluse, Henri‐Jacques Delecluse, Heike Allgayer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3363-3384 (2021)
The paucity of microbiome studies at intestinal tissues has contributed to a yet limited understanding of potential viral and bacterial cofactors of colorectal cancer (CRC) carcinogenesis or progression. We analysed whole‐genome sequences of CRC pr
Externí odkaz:
https://doaj.org/article/7de803998014476aa150c199a99be616
Autor:
Niklas Gebauer, Axel Künstner, Julius Ketzer, Hanno M. Witte, Tobias Rausch, Vladimir Benes, Jürgen Zimmermann, Judith Gebauer, Hartmut Merz, Veronica Bernard, Lana Harder, Katharina Ratjen, Stefan Gesk, Wolfgang Peter, Yannik Busch, Peter Trojok, Nikolas von Bubnoff, Harald Biersack, Hauke Busch, Alfred C. Feller
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 5, Pp 1-12 (2021)
Abstract Epstein–Barr virus (EBV)-associated diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS) constitute a distinct clinicopathological entity in the current World Health Organization (WHO) classification. However, its genomic feat
Externí odkaz:
https://doaj.org/article/aaccdd4a3f3749468865bd6a30e961c3
Autor:
Büşra Erarslan‐Uysal, Joachim B Kunz, Tobias Rausch, Paulina Richter‐Pechańska, Ianthe AEM van Belzen, Viktoras Frismantas, Beat Bornhauser, Diana Ordoñez‐Rueada, Malte Paulsen, Vladimir Benes, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner‐Schwabe, Cornelia Eckert, Tsvetomir Loukanov, Matthias Gorenflo, Sebastian M Waszak, Jean‐Pierre Bourquin, Martina U Muckenthaler, Jan O Korbel, Andreas E Kulozik
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp 1-14 (2020)
Abstract We aimed at identifying the developmental stage at which leukemic cells of pediatric T‐ALLs are arrested and at defining leukemogenic mechanisms based on ATAC‐Seq. Chromatin accessibility maps of seven developmental stages of human healt
Externí odkaz:
https://doaj.org/article/22d6864d026e473bab1f5a0e5f21e0cf
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background DNA sequencing is at the core of many molecular biology laboratories. Despite its long history, there is a lack of user-friendly Sanger sequencing data analysis tools that can be run interactively as a web application or at large-
Externí odkaz:
https://doaj.org/article/6c5482cb61494f8f8494fffee143cd34