Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Tobias R, Kollmann"'
Autor:
David Martino, Nina Kresoje, Nelly Amenyogbe, Rym Ben-Othman, Bing Cai, Mandy Lo, Olubukola Idoko, Oludare A. Odumade, Reza Falsafi, Travis M. Blimkie, Andy An, Casey P. Shannon, Sebastiano Montante, Bhavjinder K. Dhillon, Joann Diray-Arce, Al Ozonoff, Kinga K. Smolen, Ryan R. Brinkman, Kerry McEnaney, Asimenia Angelidou, Peter Richmond, Scott J. Tebbutt, the EPIC-HIPC consortium, Beate Kampmann, Ofer Levy, Robert E. W. Hancock, Amy H. Y. Lee, Tobias R. Kollmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Understanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the immunological
Externí odkaz:
https://doaj.org/article/f8167ccffdeb4b0d9144c24cdeaf6fcb
Autor:
Mario Fidanza, Julie Hibbert, Erica Acton, Danny Harbeson, Elizna Schoeman, Patrycja Skut, Tabitha Woodman, Adrien Eynaud, Lucy Hartnell, Byron Brook, Bing Cai, Mandy Lo, Reza Falsafi, Robert E. W. Hancock, Msandeni Chiume-Kayuni, Norman Lufesi, Constantin R. Popescu, Pascal M. Lavoie, Tobias Strunk, Andrew J. Currie, Tobias R. Kollmann, Nelly Amenyogbe, Amy H. Lee
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and mechanistic insights have hampered our abilities to develop prophylactic or therapeutic interventions. Biomarkers in human neonatal sepsis have been repeat
Externí odkaz:
https://doaj.org/article/b54f31f4736543a6a2fa9c599d17c04a
Autor:
Thomas S. Kouyate, Athena N. Nguyen, Alec L. Plotkin, Rebeca Ford, Olubukola T. Idoko, Oludare A. Odumade, Geraldine Masiria, Joe Jude, Joann Diray-Arce, Kerry McEnaney, Al Ozonoff, Hanno Steen, Tobias R. Kollmann, Peter C. Richmond, Anita H. J. van den Biggelaar, Beate Kampmann, William Pomat, Ofer Levy, Kinga K. Smolen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDynamic cellular and molecular adaptations in early life significantly impact health and disease. Upon birth, newborns are immediately challenged by their environment, placing urgent demands on the infant immune system. Adenosine deaminas
Externí odkaz:
https://doaj.org/article/3469119b920e45cb8cafff5b9af4ea6b
Autor:
José A. Castro-Rodriguez, Eleanor N. Fish, Samuel T. Montgomery, Tobias R. Kollmann, Carolina Iturriaga, Casey Shannon, Yuliya Karpievitch, Joseph Ho, Virginia Chen, Robert Balshaw, Rym Ben-Othman, Radhouane Aniba, Francisca Gidi-Yunge, Lucy Hartnell, David G. Hancock, Guillermo Pérez-Mateluna, Marcela Urzúa, Scott J. Tebbutt, Diego García-Huidobro, Cecilia Perret, Arturo Borzutzky, Stephen M. Stick
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102082- (2023)
Summary: Background: Accumulating evidence indicates that an early, robust type 1 interferon (IFN) response to SARS-CoV-2 is important in determining COVID-19 outcomes, with an inadequate IFN response associated with disease severity. Our objective w
Externí odkaz:
https://doaj.org/article/d8d8e7c67f0844a18d712d629bff8ce5
Autor:
Reanne M. Ho, Asha C. Bowen, Christopher C. Blyth, Allison Imrie, Tobias R. Kollmann, Stephen M. Stick, Anthony Kicic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The global population has been severely affected by the coronavirus disease 2019 (COVID-19) pandemic, however, with older age identified as a risk factor, children have been underprioritized. This article discusses the factors contributing to the les
Externí odkaz:
https://doaj.org/article/981cba2aa28a4f8383ea86693ed23833
Autor:
Paola Villanueva, Ushma Wadia, Nigel Crawford, Nicole L. Messina, Tobias R. Kollmann, Michaela Lucas, Laurens Manning, Peter Richmond, Laure F. Pittet, Nigel Curtis
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The reported frequency and types of adverse events following initial vaccination and revaccination with Bacille Calmette-Guérin (BCG) varies worldwide. Using active surveillance in a randomised controlled trial of BCG vaccination (the BRACE
Externí odkaz:
https://doaj.org/article/bfc9e101ceab4d0a838dae4f6a03123a
Autor:
Julia Strandmark, Alansana Darboe, Joann Diray-Arce, Rym Ben-Othman, Sofia M. Vignolo, Shun Rao, Kinga K. Smolen, Geert Leroux-Roels, Olubukola T. Idoko, Guzmán Sanchez-Schmitz, Al Ozonoff, Ofer Levy, Tobias R. Kollmann, Arnaud Marchant, Beate Kampmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A single birth-dose of Hepatitis B vaccine (HepB) can protect newborns from acquiring Hepatitis B infection through vertical transmission, though several follow-up doses are required to induce long-lived protection. In addition to stimulating antibod
Externí odkaz:
https://doaj.org/article/18f04a70e1674e919905aded5c30ad0c
Autor:
Carolina Iturriaga, Nat Eiffler, Rad Aniba, Rym Ben-Othman, Guillermo Perez-Mateluna, Jessica K. V. Meyer, Eleanor N. Fish, Tobias R. Kollmann, Nicolas Severino, Stephen Stick, Arturo Borzutzky, Cecilia Perret, José A. Castro-Rodriguez, Diego Garcia-Huidobro
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background SARS-CoV-2 infection rapidly spreads in populations due to the high rates of community transmission. Interrupting the shedding of SARS-CoV-2 may reduce the incidence of Coronavirus Disease 19 (COVID-19). Herein we provide a protoc
Externí odkaz:
https://doaj.org/article/60f714c94caf4155b56bf4aac058f1d8
Autor:
Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa I Labzin, Tejasri Yarlagadda, Alexander A Khromykh, Xiaohui Wang, Julian D J Sng, Claudia J Stocks, Yao Xia, Tobias R Kollmann, David Martino, Merja Joensuu, Frédéric A Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C Bowen, Anthony Kicic, Peter D Sly, Kirsten M Spann, Kirsty R Short
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001728 (2022)
Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a26c38131664476296b2cb3b91aefadf
Autor:
Joann Diray-Arce, Asimenia Angelidou, Kristoffer Jarlov Jensen, Maria Giulia Conti, Rachel S. Kelly, Matthew A. Pettengill, Mark Liu, Simon D. van Haren, Scott D. McCulloch, Greg Michelloti, Olubukola Idoko, Tobias R. Kollmann, Beate Kampmann, Hanno Steen, Al Ozonoff, Jessica Lasky-Su, Christine S. Benn, Ofer Levy
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110772- (2022)
Summary: Vaccines have generally been developed with limited insight into their molecular impact. While systems vaccinology enables characterization of mechanisms of action, these tools have yet to be applied to infants, who are at high risk of infec
Externí odkaz:
https://doaj.org/article/d0c46f541a054652876a5e94cbd057cb