Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tobias Mittelstaedt"'
Autor:
Elena Alvarez-Baron, Thoralf Opitz, Tobias Mittelstaedt, Susanne Schoch, Katrin Michel, Heinz Beck, Dirk Dietrich, Albert J. Becker, Frank Schmitz
Publikováno v:
The journal of neuroscience 33(2), 824-839 (2013). doi:10.1523/JNEUROSCI.2229-12.2013
The large isoforms of the Rab3 interacting molecule (RIM) family, RIM1α/β and RIM2α/β, have been shown to be centrally involved in mediating presynaptic active zone function. The RIM protein family contains two additional small isoforms, RIM3γ a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c2c725a266f0baa61bd32903ff7acf
https://doi.org/10.1523/jneurosci.2229-12.2013
https://doi.org/10.1523/jneurosci.2229-12.2013
Autor:
Albert J. Becker, Pitt Niehusmann, Jan Felix Drexler, Tobias Mittelstaedt, Christian G. Bien, Susanne Schoch, Alexander Grote
Publikováno v:
Epilepsia. 51:2478-2483
Temporal lobe epilepsy (TLE) is frequently associated with mesial temporal sclerosis (MTS). Many etiologic aspects of TLE are still unresolved. Here, we aimed to analyze the presence of human herpes virus 6 (HHV-6) DNA in distinct TLE pathologies. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4006fe8cc6f1550456f3667fdb4b2558
https://doi.org/10.1111/j.1528-1167.2010.02741.x
https://doi.org/10.1111/j.1528-1167.2010.02741.x
Publikováno v:
The Journal of comparative neurology. 519(15)
The members of the Liprin-α protein family, Liprin-α1-4, are scaffolding proteins that play important roles in the regulation of synapse assembly and maturation, vesicular trafficking, and cell motility. Recent evidence suggests that despite their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b350de63e37d2ed140017716a55996
https://pubmed.ncbi.nlm.nih.gov/21618221
https://pubmed.ncbi.nlm.nih.gov/21618221
Autor:
Pitt, Niehusmann, Tobias, Mittelstaedt, Christian G, Bien, Jan F, Drexler, Alexander, Grote, Susanne, Schoch, Albert J, Becker
Publikováno v:
Epilepsia. 51(12)
Temporal lobe epilepsy (TLE) is frequently associated with mesial temporal sclerosis (MTS). Many etiologic aspects of TLE are still unresolved. Here, we aimed to analyze the presence of human herpes virus 6 (HHV-6) DNA in distinct TLE pathologies. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::843e6fd7791f54ac21be1d4988f1a3d2
https://pubmed.ncbi.nlm.nih.gov/21204811
https://pubmed.ncbi.nlm.nih.gov/21204811
Publikováno v:
Biological Chemistry. 391
Active zones are specialized areas of the plasma membrane in the presynaptic nerve terminal that mediate neurotransmitter release and synaptic plasticity. The multidomain proteins RIM1 and RIM2 are integral components of the cytomatrix at the active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a3e2708c81be031493ee6b89ed364e
https://doi.org/10.1515/bc.2010.064
https://doi.org/10.1515/bc.2010.064
The cytomatrix at the active zone is a complex proteinaceous network involved in the regulation of docking, priming, and fusion of synaptic vesicles. ELKS, liprins, and Rab3-interacting molecule binding proteins (RIM-BPs) are three of the six protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc35d72709d9bc0fb75b84ae76ca839a
https://doi.org/10.1016/b978-008045046-9.01369-3
https://doi.org/10.1016/b978-008045046-9.01369-3
Autor:
Susanne Schoch, Tobias Mittelstaedt
Publikováno v:
Gene. 403(1-2)
RIM-binding proteins (RIM-BPs) were identified as binding partners of the presynaptic active zone proteins RIMs as well as for voltage-gated Ca2+-channels. They were suggested to form a functional link between the synaptic-vesicle fusion apparatus an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382a5c148a1442c784ff6c466c3175ba
https://pubmed.ncbi.nlm.nih.gov/17855024
https://pubmed.ncbi.nlm.nih.gov/17855024
Autor:
Susanne Schoch, Pascal S. Kaeser, Nicole Feldmann, Frank Schmitz, Robert E. Hammer, Weichun Lin, Thomas C. Südhof, Daniel Padgett, Weiping Han, Pablo E. Castillo, Vivien Chevaleyre, Tobias Mittelstaedt
Publikováno v:
The EMBO journal. 25(24)
Alpha-RIMs (RIM1alpha and RIM2alpha) are multidomain active zone proteins of presynaptic terminals. Alpha-RIMs bind to Rab3 on synaptic vesicles and to Munc13 on the active zone via their N-terminal region, and interact with other synaptic proteins v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dffd3fc77a1d581da774de13445863a
https://pubmed.ncbi.nlm.nih.gov/17124501
https://pubmed.ncbi.nlm.nih.gov/17124501