Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Tobias Ma"'
Autor:
Ashish Goyal, Jens Bauer, Joschka Hey, Dimitris N. Papageorgiou, Ekaterina Stepanova, Michael Daskalakis, Jonas Scheid, Marissa Dubbelaar, Boris Klimovich, Dominic Schwarz, Melanie Märklin, Malte Roerden, Yu-Yu Lin, Tobias Ma, Oliver Mücke, Hans-Georg Rammensee, Michael Lübbert, Fabricio Loayza-Puch, Jeroen Krijgsveld, Juliane S. Walz, Christoph Plass
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Immunotherapies targeting cancer-specific neoantigens have revolutionized the treatment of cancer patients. Recent evidence suggests that epigenetic therapies synergize with immunotherapies, mediated by the de-repression of endogenous retrov
Externí odkaz:
https://doaj.org/article/78cbaff3798a429b8d0dd2100c9a8172
Autor:
Gabriele Greve, Geoffroy Andrieux, Pascal Schlosser, Nadja Blagitko-Dorfs, Usama-Ur Rehman, Tobias Ma, Dietmar Pfeifer, Gerhard Heil, Andreas Neubauer, Jürgen Krauter, Michael Heuser, Helmut R. Salih, Konstanze Döhner, Hartmut Döhner, Björn Hackanson, Melanie Boerries, Michael Lübbert
Publikováno v:
Leukemia. 37:1018-1027
Despite routine use of DNA-hypomethylating agents (HMAs) in AML/MDS therapy, their mechanisms of action are not yet unraveled. Pleiotropic effects of HMAs include global methylome and transcriptome changes. We asked whether in blasts and T-cells from
Autor:
Helena Bresser, Usama-Ur Rehman, Julia Schüler, Anne Rubarth, Tobias Ma, Gabriele Greve, Heiko Becker, Michael Lübbert
Publikováno v:
Blood. 140:11537-11539
Autor:
Helene Michenthaler, Kalina Duszka, Isabel Reinisch, Markus Galhuber, Elisabeth Moyschewitz, Sarah Stryeck, Tobias Madl, Andreas Prokesch, Jelena Krstic
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Dietary restriction (DR) has multiple beneficial effects on health and longevity and can also improve the efficacy of certain therapies. Diets used to instigate DR are diverse and the corresponding response is not uniformly measur
Externí odkaz:
https://doaj.org/article/070ac950cd4c4ea7892e717d035f7fe9
Autor:
Sonia Grigorascu, Thomas Langbein, Isabel Rauscher, Calogero D’Alessandria, Tobias Maurer, Türkay Hekimsoy, Wolfgang A Weber, Matthias Eiber
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-6 (2024)
Externí odkaz:
https://doaj.org/article/30c2ed484c634ed58ca5a9acb1035fa3
Autor:
Tobias Mahler
Publikováno v:
Oslo Law Review, Vol 11, Iss 1, Pp 1-18 (2024)
This paper aims to unpack the role the newly adopted EU Machinery Regulation plays in ensuring the safety of smart robots incorporating artificial intelligence (AI). Replacing the EU Machinery Directive of 2006, this Regulation signifies a necessary
Externí odkaz:
https://doaj.org/article/8c1970ab10e14a679ea28c0a909988e1
Autor:
Harald Hornegger, Aleksandra S. Anisimova, Adnan Muratovic, Benjamin Bourgeois, Elena Spinetti, Isabell Niedermoser, Roberto Covino, Tobias Madl, G. Elif Karagöz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract The insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) is a conserved RNA-binding protein that regulates RNA stability, localization and translation. IGF2BP1 is part of various ribonucleoprotein (RNP) condensates. However, the mec
Externí odkaz:
https://doaj.org/article/36ec9943f4844727a70012fe37dd092c
Autor:
Mir Henglin, Maryam Ghareghani, William T. Harvey, David Porubsky, Sergey Koren, Evan E. Eichler, Peter Ebert, Tobias Marschall
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Haplotype information is crucial for biomedical and population genetics research. However, current strategies to produce de novo haplotype-resolved assemblies often require either difficult-to-acquire parental data or an intermediate haploty
Externí odkaz:
https://doaj.org/article/3512fe7340b944e4bcccd787429f9cff
Autor:
Tobias Maierhofer, Sönke Scherzer, Armando Carpaneto, Thomas D. Müller, Jose M. Pardo, Inga Hänelt, Dietmar Geiger, Rainer Hedrich
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Plants can survive in soils of low micromolar potassium (K+) concentrations. Root K+ intake is accomplished by the K+ channel AKT1 and KUP/HAK/KT type high-affinity K+ transporters. Arabidopsis HAK5 mutants impaired in low K+ acquisition hav
Externí odkaz:
https://doaj.org/article/01a574de312541b289fe9987f506bab7
Autor:
Georgia Lenihan‐Geels, Francisco Garcia Carrizo, Marina Leer, Sabrina Gohlke, Moritz Oster, Sophie Pöhle‐Kronawitter, Christiane Ott, Alexandra Chadt, Isabel N. Reinisch, Markus Galhuber, Chen Li, Wenke Jonas, Markus Jähnert, Susanne Klaus, Hadi Al‐Hasani, Tilman Grune, Annette Schürmann, Tobias Madl, Andreas Prokesch, Michael Schupp, Tim J. Schulz
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1772-1784 (2024)
Abstract Background The ability of skeletal muscle to respond adequately to changes in nutrient availability, known as metabolic flexibility, is essential for the maintenance of metabolic health and loss of flexibility contributes to the development
Externí odkaz:
https://doaj.org/article/6dc15b690f604a70b8d64e36ef498037