Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Tobias Lange"'
Autor:
Guido Lewik, Gerrit Lewik, Lena S. Müller, Alexander von Glinski, Tobias L. Schulte, Tobias Lange
Publikováno v:
Spine Surgery and Related Research, Vol 8, Iss 2, Pp 133-142 (2024)
Postoperative epidural fibrosis (EF) is still a major limitation to the success of spine surgery. Fibrotic adhesions in the epidural space, initiated via local trauma and inflammation, can induce difficult-to-treat pain and constitute the main cause
Externí odkaz:
https://doaj.org/article/d0e163eb80f04843a24502e370fb60b3
Autor:
Arun Everest‐Dass, Stepan Nersisyan, Hanna Maar, Victor Novosad, Jennifer Schröder‐Schwarz, Vera Freytag, Johanna L. Stuke, Mia C. Beine, Alina Schiecke, Marie‐Therese Haider, Malte Kriegs, Omar Elakad, Hanibal Bohnenberger, Lena‐Christin Conradi, Maria Raygorodskaya, Linda Krause, Mark vonItzstein, Alexander Tonevitsky, Udo Schumacher, Diana Maltseva, Daniel Wicklein, Tobias Lange
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 62-90 (2024)
Hematogenous metastasis limits the survival of colorectal cancer (CRC) patients. Here, we illuminated the roles of CD44 isoforms in this process. Isoforms 3 and 4 were predominantly expressed in CRC patients. CD44 isoform 4 indicated poor outcome and
Externí odkaz:
https://doaj.org/article/c19589a2bdca416b84704f2b8e082ac3
Autor:
Sandra Genduso, Vera Freytag, Daniela Schetler, Lennart Kirchner, Alina Schiecke, Hanna Maar, Daniel Wicklein, Florian Gebauer, Katharina Bröker, Christine Stürken, Karin Milde-Langosch, Leticia Oliveira-Ferrer, Franz L. Ricklefs, Florian Ewald, Gerrit Wolters-Eisfeld, Kristoffer Riecken, Ludmilla Unrau, Linda Krause, Hanibal Bohnenberger, Anne Offermann, Sven Perner, Susanne Sebens, Katrin Lamszus, Linda Diehl, Stefan Linder, Manfred Jücker, Udo Schumacher, Tobias Lange
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-24 (2023)
Abstract Background The immunological composition of the tumor microenvironment has a decisive influence on the biological course of cancer and is therefore of profound clinical relevance. In this study, we analyzed the cooperative effects of integri
Externí odkaz:
https://doaj.org/article/15a2e60098c04388b2f1c864ee3b2031
Publikováno v:
Cement, Vol 12, Iss , Pp 100064- (2023)
Studies on the properties of pure C3A phases are often limited to methods requiring small sample amounts due to the lack of a convenient laboratory synthesis yielding sample amounts exceeding 100 g. Here, we report a simple and large scale lab method
Externí odkaz:
https://doaj.org/article/d738071f0609491daf313f3fb9966067
Autor:
Omar Elakad, Björn Häupl, Vera Labitzky, Sha Yao, Stefan Küffer, Alexander von Hammerstein-Equord, Bernhard C. Danner, Manfred Jücker, Henning Urlaub, Tobias Lange, Philipp Ströbel, Thomas Oellerich, Hanibal Bohnenberger
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-14 (2022)
Abstract Lung cancer is the leading cause of cancer-related deaths worldwide. Fibroblast growth factor receptor 1 (FGFR1) gene amplification is one of the most prominent and potentially targetable genetic alterations in squamous-cell lung cancer (SQC
Externí odkaz:
https://doaj.org/article/95f49f3dedb14887b6c8d296c622f61d
Autor:
Tanja Spethmann, Lukas Clemens Böckelmann, Vera Labitzky, Ann‐Kristin Ahlers, Jennifer Schröder‐Schwarz, Sarah Bonk, Ronald Simon, Guido Sauter, Hartwig Huland, Robert Kypta, Udo Schumacher, Tobias Lange
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1956-1969 (2021)
Both oncogenic and tumor suppressor functions have been described for junction plakoglobin (JUP), also known as γ‐catenin. To clarify the role of JUP in prostate cancer, JUP protein expression was immunohistochemically detected in a tissue microar
Externí odkaz:
https://doaj.org/article/7121450caf7b4f2591affd5fcf9ae787
Autor:
Marius Kemper, Alina Schiecke, Hanna Maar, Sergey Nikulin, Andrey Poloznikov, Vladimir Galatenko, Michael Tachezy, Florian Gebauer, Tobias Lange, Kristoffer Riecken, Alexander Tonevitsky, Achim Aigner, Jakob Izbicki, Udo Schumacher, Daniel Wicklein
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Mesothelial E- and P-selectins substantially mediate the intraperitoneal spread of Pancreatic ductal adenocarcinoma (PDA) cells in xenograft models. In the absence of selectins in the host, the integrin subunit alpha-V (ITGAV, CD5
Externí odkaz:
https://doaj.org/article/74ad8fbecb82403c9e846f168a4d146c
Autor:
Matthias Lubnow, Barbara Schmidt, Martin Fleck, Bernd Salzberger, Thomas Müller, Georg Peschel, Roland Schneckenpointner, Tobias Lange, Florian Hitzenbichler, Martin Kieninger, Dirk Lunz, Bernhard Graf, Christoph Brochhausen, Florian Weber, Florian Lüke, David Peterhoff, Philipp Schuster, Andreas Hiergeist, Robert Offner, Ute Hehr, Stefan Wallner, Frank Hanses, Stephan Schmid, Kilian Weigand, Florian Geismann, Hendrik Poeck, Tobias Pukrop, Matthias Evert, Andre Gessner, Ralph Burkhardt, Wolfgang Herr, Lars S. Maier, Daniel Heudobler
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss , Pp 624-627 (2021)
A 21-year-old woman was hospitalized due to coronavirus disease 2019 (COVID-19)-associated respiratory and hepatic impairment concomitant with severe hemolytic anemia. Upon diagnosis of secondary hemophagocytic lymphohistiocytosis, immunosuppression
Externí odkaz:
https://doaj.org/article/1e6ad5d41aa74c868cb07ceeb8722c90
Autor:
Paula Schäfer, Stefanie Muhs, Lucas Turnbull, Palwasha Garwal, Hanna Maar, Timur A. Yorgan, Eva Tolosa, Tobias Lange, Sabine Windhorst
Publikováno v:
Cancers, Vol 15, Iss 4, p 1274 (2023)
Tumor plasticity is essential for adaptation to changing environmental conditions, in particular during the process of metastasis. In this study, we compared morphological and biochemical differences between LAN-1 neuroblastoma (NB) cells recovered f
Externí odkaz:
https://doaj.org/article/49d8d8cbc8d840bf96953c69e5bb04a6
Autor:
Bertin Hoffmann, Tobias Lange, Vera Labitzky, Kristoffer Riecken, Andreas Wree, Udo Schumacher, Gero Wedemann
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Xenograft mouse tumor models are used to study mechanisms of tumor growth and metastasis formation and to investigate the efficacy of different therapeutic interventions. After injection the engrafted cells form a local tumor nodu
Externí odkaz:
https://doaj.org/article/dae8d1450437440986b81d0d0bcff154