Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Tobias Janowitz"'
Autor:
Qingtao Sun, Daniëlle van de Lisdonk, Miriam Ferrer, Bruno Gegenhuber, Melody Wu, Youngkyu Park, David A. Tuveson, Jessica Tollkuhn, Tobias Janowitz, Bo Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Interleukin-6 (IL-6) has been long considered a key player in cancer cachexia. It is believed that sustained elevation of IL-6 production during cancer progression causes brain dysfunctions, which ultimately result in cachexia. However, how
Externí odkaz:
https://doaj.org/article/0ffe8eb9112f497da2e4fea49fef27ae
Autor:
Joseph R. Merrill, Alessandra Inguscio, Taemoon Chung, Breanna Demestichas, Libia A. Garcia, Jill Habel, David Y. Lewis, Tobias Janowitz, Scott K. Lyons
Publikováno v:
Cell Stress, Vol 7, Iss 8, Pp 59-68 (2023)
Non-invasive imaging of tumors expressing reporter transgenes is a popular preclinical method for studying tumor development and response to therapy in vivo due to its ability to distinguish signal from tumors over background noise. However, the util
Externí odkaz:
https://doaj.org/article/48a7a68f22f346339e6f85ed6593c731
Autor:
Sam O. Kleeman, Mattia Cordioli, Paul R.H. J. Timmers, Atlas Khan, Pinkus Tober-Lau, Florian Kurth, Vadim Demichev, Hannah V. Meyer, James F. Wilson, Markus Ralser, Krzysztof Kiryluk, Andrea Ganna, Kenneth Baillie, Tobias Janowitz
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105040- (2022)
Summary: COVID-19 has highly variable clinical courses. The search for prognostic host factors for COVID-19 outcome is a priority. We performed logistic regression for ICU admission against a polygenic score (PGS) for Cystatin C (CyC) production in p
Externí odkaz:
https://doaj.org/article/98412ddd74424a88ad534e78aa114bfa
Autor:
Dongyan Song, Jose M. Adrover, Christy Felice, Lisa N. Christensen, Xue-Yan He, Joseph R. Merrill, John E. Wilkinson, Tobias Janowitz, Scott K. Lyons, Mikala Egeblad, Nicholas K. Tonks
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Acute lung injury (ALI) can cause acute respiratory distress syndrome (ARDS), a lethal condition with limited treatment options and currently a common global cause of death due to COVID-19. ARDS secondary to transfusion-related ALI (TRALI) has been r
Externí odkaz:
https://doaj.org/article/9a755f6522ea47d481f935c94edc60d1
Autor:
Hafsa Munir, James O. Jones, Tobias Janowitz, Markus Hoffmann, Maximilien Euler, Carla P. Martins, Sarah J. Welsh, Jacqueline D. Shields
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The tumor microenvironment is composed of many cell types that crosstalk to modulate local immunity. Here the authors show that Amyloid β proteins from cancer-associated fibroblasts (CAF) induce neutrophil extracellular trap (NET) production by neut
Externí odkaz:
https://doaj.org/article/2556fc9e34b0446f9be86ba29dd43111
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-7 (2020)
Abstract Background Mechanically ventilated patients with COVID-19 have a mortality of 24–53%, in part due to distal mucopurulent secretions interfering with ventilation. DNA from neutrophil extracellular traps (NETs) contribute to the viscosity of
Externí odkaz:
https://doaj.org/article/ea3656d9d7df4a9fa2ca0e4e0b30b0f1
Autor:
Claire M. Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I. Jodrell
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancreatic adenosquamous c
Externí odkaz:
https://doaj.org/article/86cf2c1eac3c4602ab92688f5efeb013
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84336 (2014)
Traumatic brain injury (TBI) is an important public health problem, comparable to stroke in incidence and prevalence. Few interventions have proven efficacy in TBI, and clinical trials are, therefore, necessary to advance management in TBI. We descri
Externí odkaz:
https://doaj.org/article/185f3ff6d42b476c9f4f1a23b61f64aa
Autor:
Miriam Ferrer, Tracy G. Anthony, Janelle S. Ayres, Giulia Biffi, Justin C. Brown, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Anthony P. Coll, Richard F. Dunne, Marcus D. Goncalves, Jonas Grethlein, Steven B. Heymsfield, Sheng Hui, Mariam Jamal-Hanjani, Jie Min Lam, David Y. Lewis, David McCandlish, Karen M. Mustian, Stephen O’Rahilly, Norbert Perrimon, Eileen P. White, Tobias Janowitz
Publikováno v:
Cell. 186:1824-1845
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df74b60a74581bc8dfcac2f5b065f22d
https://doi.org/10.1016/j.cell.2023.03.028
https://doi.org/10.1016/j.cell.2023.03.028
Autor:
Haiwei Mou, Onur Eskiocak, Kadir A. Özler, Megan Gorman, Junjiayu Yue, Ying Jin, Zhikai Wang, Ya Gao, Tobias Janowitz, Hannah V. Meyer, Tianxiong Yu, John E Wilkinson, Alper Kucukural, Deniz M. Ozata, Semir Beyaz
Publikováno v:
The Journal of Pathology. 259:415-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a3d935a41688f7144c00508f93fb4c
https://doi.org/10.1002/path.6054
https://doi.org/10.1002/path.6054