Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tobias Hohl"'
Autor:
Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys I. Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Dominic Helm, Martin Schneider, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Linking clinical multi-omics with mechanistic studies may improve the understanding of rare cancers. We leverage two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effec
Externí odkaz:
https://doaj.org/article/2ecd072ff8db496d9a6745bf800ae284
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 8, p e1007230 (2019)
Most biological systems are difficult to analyse due to a multitude of interacting components and the concomitant lack of information about the essential dynamics. Finding appropriate models that provide a systematic description of such biological sy
Externí odkaz:
https://doaj.org/article/41885b331a164df1aadd08ea1291c0b4
Publikováno v:
Bio-Protocol, Vol 6, Iss 18 (2016)
Aspergillus fumigatus is a ubiquitous fungal pathogen that forms airborne conidia. The process of restricting conidial germination into hyphae by lung leukocytes is critical in determining infectious outcomes. Tracking the outcome of conidia-host cel
Externí odkaz:
https://doaj.org/article/8de91e9305ef47a79fa6a674413e2ba7
Autor:
Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl
Linking clinical multi-omics analyses with mechanistic studies provides opportunities to explore the pathogenesis of rare cancers. We leveraged two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68c8e0119589935f1ce8f78e158a8813
https://doi.org/10.1101/2023.02.19.528670
https://doi.org/10.1101/2023.02.19.528670
Autor:
Julia Schoepf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav Diwan, Zunamys Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl
Publikováno v:
Cancer Research. 83:4544-4544
Rhabdomyosarcoma (RMS) is a soft-tissue sarcoma subtype composed of malignant immature precursor cells with myogenic differentiation defined by aberrant expression of the transcription factors MYOD1 and MYOG. Four subtypes are distinguished, characte
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 15, Iss 8, p e1007230 (2019)
PLoS Computational Biology, Vol 15, Iss 8, p e1007230 (2019)
Most biological systems are difficult to analyse due to a multitude of interacting components and the concomitant lack of information about the essential dynamics. Finding appropriate models that provide a systematic description of such biological sy
Autor:
Elena Aikawa, Florian Schlotter, Marc R. Dweck, Joshua D. Hutcheson, Marie Foley Kijewski, Carlos J. Alcaide-Corral, Mi-Ae Park, David E. Newby, Lang H Lee, Sasha A Singh, Masanori Aikawa, Michael D. Creager, Marcelo F. Di Carli, Mark C. Blaser, Alastair J Moss, Adriana Tavares, Tobias Hohl
Publikováno v:
Creager, M D, Hohl, T, Hutcheson, J D, Moss, A J, Schlotter, F, Blaser, M C, Park, M-A, Lee, L H, Singh, S A, Alcaide-Corral, C J, Tavares, A A S, Newby, D E, Kijewski, M F, Aikawa, M, Di Carli, M, Dweck, M R & Aikawa, E 2019, ' 18 F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images ', Circulation: Cardiovascular Imaging, vol. 12, no. 1, e007835 . https://doi.org/10.1161/CIRCIMAGING.118.007835
Background: Microcalcifications in atherosclerotic plaques are destabilizing, predict adverse cardiovascular events, and are associated with increased morbidity and mortality. 18 F-fluoride positron emission tomography (PET)/computed tomography (CT)
Autor:
Joshua J. Obar, Alayna Katherine Caffrey, Xi Wang, Vanessa Espinosa, Yi-Wei Tang, Tobias Hohl, Amariliz Rivera, Robert Cramer
Publikováno v:
The Journal of Immunology. 200:52.23-52.23
Type I and III interferons act as important activators of antifungal neutrophil response in the lungs. The RIG-I like receptor (RLR) family, including RIG-I and Mda5, are cytosolic RNA sensors that signal through the MAVS adaptor in order to activate
Autor:
Joshua J Obar, Alayna Katherine Caffrey-Carr, Caitlin Kowalski, Sarah Beattie, Nathan Blaseg, Chanell Upshaw, Yi-Wei Tang, Tobias Hohl, Robert Cramer
Publikováno v:
The Journal of Immunology. 198:77.6-77.6
Aspergillus fumigatus strain diversity is reflected in heterogeneous virulence and inflammatory responses. Mechanisms underlying A. fumigatus strain specific immune responses and how this affects disease outcome is unresolved. We observe that the CEA
Autor:
Tobias Hohl, Bruno Jeitzinger
Publikováno v:
Swiss Political Science Review. 3:1-27
Party affiliation as the standard measure of political preferences of Swiss legislators is associated with several problems. To overcome these problems the authors develop ratings for members of the National Council, based on roll-call votes. They di