Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Tobias Heß"'
Autor:
Daniel Zakowiecki, Peter Edinger, Markos Papaioannou, Michael Wagner, Tobias Hess, Jadwiga Paszkowska, Marcela Staniszewska, Daria Myslitska, Michal Smolenski, Justyna Dobosz, Grzegorz Garbacz, Dorota Haznar Garbacz
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1485 (2024)
Background/Objectives: The aim of the present study was to develop lactose-free formulations of rivaroxaban, a novel oral anticoagulant used for the treatment and prevention of blood clotting. As a BCS Class II drug, rivaroxaban is characterized by p
Externí odkaz:
https://doaj.org/article/be3cd09a86c64588bf6c844079d2c974
Publikováno v:
Life, Vol 14, Iss 7, p 810 (2024)
Ankle sprains are the most frequently occurring musculoskeletal injuries among recreational athletes. Ankle support through bandages following the initial orthotic treatment might be beneficial for rehabilitation purposes. However, the literature is
Externí odkaz:
https://doaj.org/article/745dfcb183024d13aed310af40db6bdc
Publikováno v:
Brain Sciences, Vol 13, Iss 12, p 1681 (2023)
Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to axial motor symptoms in Parkinson’s disease (PD) and whether anti-parkinsonian medication and subthalamic nucleus deep brain stimulation (STN-DBS) show
Externí odkaz:
https://doaj.org/article/df9d0919e895410d8af71a85949bc38b
Autor:
Daniel Zakowiecki, Peter Edinger, Tobias Hess, Jadwiga Paszkowska, Marcela Staniszewska, Svitlana Romanova, Grzegorz Garbacz
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2224 (2023)
Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure, process dynamics, or the temperature generated. In the present study, pancreatin was employed as a mode
Externí odkaz:
https://doaj.org/article/38d592463c8a43c78d90e7b5ba9b2153
Autor:
Daniel Zakowiecki, Margarethe Richter, Ceren Yuece, Annika Voelp, Maximilian Ries, Markos Papaioannou, Peter Edinger, Tobias Hess, Krystyna Mojsiewicz-Pieńkowska, Krzysztof Cal
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1265 (2023)
Continuous manufacturing is becoming the new technological standard in the pharmaceutical industry. In this work, a twin-screw processor was employed for the continuous production of liquisolid tablets containing either simethicone or a combination o
Externí odkaz:
https://doaj.org/article/1a54c7a6b4334e1a98b533798ab3fc01
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 454 (2023)
Background: Postural instability is one of the most restricting motor symptoms for patients with Parkinson’s disease (PD). While medication therapy only shows minor effects, it is still unclear whether medication in conjunction with deep brain stim
Externí odkaz:
https://doaj.org/article/1a75b4f876cc4708abab1cc45efe5597
Autor:
Krzysztof Cal, Barbara Mikolaszek, Tobias Hess, Markos Papaioannou, Joanna Lenik, Patrycja Ciosek-Skibińska, Helene Wall, Jadwiga Paszkowska, Svitlana Romanova, Grzegorz Garbacz, Daniel Zakowiecki
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 242 (2023)
Sprinkle formulations represent an interesting concept of medicinal products aimed at the steadily growing population of patients suffering from swallowing difficulties (dysphagia). In the present work, immediate-release sprinkle MUPS (multiple-unit
Externí odkaz:
https://doaj.org/article/2614d5c6acba4493b2fa560e21d027ab
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e05811- (2021)
Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to postural disturbance in idiopathic normal pressure hydrocephalus (iNPH). Methods: Three different groups were tested: iNPH-patients (iNPH), iNPH-patients
Externí odkaz:
https://doaj.org/article/0b5c1716abf54895a7579c00a3e8b9f6
Autor:
Daniel Zakowiecki, Peter Edinger, Markos Papaioannou, Tobias Hess, Bartlomiej Kubiak, Anna Terlecka
Publikováno v:
Pharmaceutical Development and Technology. 27:702-713
Direct compression (DC) is the simplest and most economical way to produce pharmaceutical tablets. Ideally, it consists of only two steps: dry blending of a drug substance(s) with excipients followed by compressing the powder mixture into tablets. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02318e1b322c08868ae42562017ebc5
https://doi.org/10.1080/10837450.2022.2107013
https://doi.org/10.1080/10837450.2022.2107013
Autor:
Daniel Zakowiecki, Maja Frankiewicz, Tobias Hess, Krzysztof Cal, Maciej Gajda, Justyna Dabrowska, Bartlomiej Kubiak, Jadwiga Paszkowska, Marcela Wiater, Dagmara Hoc, Grzegorz Garbacz, Dorota Haznar-Garbacz
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 805 (2021)
Novel calcium phosphate-based starter pellets were used to develop a biphasic-release multiple-unit pellet system (MUPS) with diclofenac sodium as a model drug in the form of hard gelatin capsules. For comparative purposes, corresponding formulations
Externí odkaz:
https://doaj.org/article/38db019efbd34125be646d5d35787b60